ANALISIS KEBUTUHAN PENGEMBANGAN BUKU SAKU BIOLOGI BERBASIS MIND MAP (BIOMAP)

Autor: Ade Suryanda, Eka Putri Azrai, Anita Julita

Publikováno v: Jurnal Pendidikan Matematika dan IPA, Vol 11, Iss 1, Pp 86-98 (2020)

Pocketbook based on Mind Map is a supporting book with a size smaller than the standard size, which is systematically in accordance with the working principle of the brain and does not require extensive space in storing it. The aims of studies to exp

Externí odkaz: https://doaj.org/article/df49127a93bb48e999d0756409609e32

The DHODH inhibitor PTC299 arrests SARS-CoV-2 replication and suppresses induction of inflammatory cytokines

Autor: Caterina Strambio-De-Castillia, Stuart W. Peltz, Christopher R. Trotta, Joseph M. Colacino, Elizabeth Goodwin, Liangxian Cao, Yetao Wang, Ellen L Suder, Elke Mühlberger, Sina Bavari, Jason D. Graci, Allan Jacobson, Mark Pykett, Kylie O'Keefe, Rachel A. Sattler, Ronald Kong, Ellen Welch, Jeremy Luban, Katherine Cintron-Lue, Marla Weetall, Slobodan Paessler, Veronica Soloveva, Nikolai Naryshkin

Publikováno v: Virus Research
bioRxiv

Highlights • COVID-19 is typified by SARS-CoV-2 replication and excessive inflammatory response. • PTC299 is small orally available DHODH inhibitor that blocks pyrimidine synthesis. • PTC299 is potent inhibitor of the replication of SARS-CoV-2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3cffc893d893918d7de424f44edd7c5
https://doi.org/10.1016/j.virusres.2020.198246

Org 214007-0: a novel non-steroidal selective glucocorticoid receptor modulator with full anti-inflammatory properties and improved therapeutic index

Autor: Martin J. Smit, Jacob de Vlieg, Ruben L. Smeets, René C. van Schaik, Hans van der Maaden, Willem G.E.J. Schoonen, Constant A. A. van Boeckel, Rein Dijkema, Wynand Alkema, Theo H. van Dijk, Scott J. Lusher, Claudia L. Hofstra, Annemieke M. H. Boots, Wim H. A. Dokter, Benno A. Ingelse, Marcel van Duin, Folkert Kuipers, Paolo Conti, Christan G.J.M. Jans, Marie-Jose van Lierop, C. Marco Timmers, Ralf Plate, Aldo Grefhorst, Ross McGuire, Anke J. Laskewitz

Publikováno v: PLoS ONE, 7(11):e48385. Public Library of Science
PLoS ONE, 7(11):e48385. PUBLIC LIBRARY SCIENCE
PLoS ONE, Vol 7, Iss 11, p e48385 (2012)
PLoS One, 7
PLoS ONE
PLoS ONE, 7(11). Public Library of Science
PLoS One, 7, 11
PLoS One (print), 7(11). Public Library of Science

Contains fulltext : 103595.pdf (Publisher’s version ) (Open Access) Glucocorticoids (GCs) such as prednisolone are potent immunosuppressive drugs but suffer from severe adverse effects, including the induction of insulin resistance. Therefore, deve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f4a324fb2b1362114eafd292311c633
https://doi.org/10.1371/journal.pone.0048385

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