Zobrazeno 1 - 10
of 257
pro vyhledávání: '"biological targets"'
Publikováno v:
Molecular Biomedicine, Vol 5, Iss 1, Pp 1-21 (2024)
Abstract Radiotherapy is a pivotal intervention for cancer patients, significantly impacting their treatment outcomes and survival prospects. Nevertheless, in the course of treating those with abdominal, pelvic, or retroperitoneal malignant tumors, t
Externí odkaz:
https://doaj.org/article/3cbec39bf7ec4ba5b42c8118ff542d1b
Publikováno v:
PeerJ Computer Science, Vol 10, p e2271 (2024)
To address the challenge of suboptimal object detection outcomes stemming from the deformability of marine flexible biological entities, this study introduces an algorithm tailored for detecting marine flexible biological targets. Initially, we compi
Externí odkaz:
https://doaj.org/article/d44f0ea3859a4b929e9cdd79b4b3b8ac
Autor:
Mohsina Patwekar, Faheem Patwekar, Anuradha Medikeri, Shaikh Daniyal, Mohammad A. Kamal, Gulzar Ahmed Rather, Rohit Sharma
Publikováno v:
Exploration of Medicine, Vol 4, Iss 5, Pp 637-663 (2023)
Complex enzyme interactions play a role in the spread of cancer, a process fueled by unregulated cell proliferation. DNA topoisomerases, which are important for fixing DNA topological problems, have drawn a lot of interest as potential targets for an
Externí odkaz:
https://doaj.org/article/41d17429dab24ca7b0a6896c15ca2a93
Publikováno v:
MedComm, Vol 4, Iss 5, Pp n/a-n/a (2023)
Abstract Tuberculosis (TB) remains a significant public health concern in the 21st century, especially due to drug resistance, coinfection with diseases like immunodeficiency syndrome (AIDS) and coronavirus disease 2019, and the lengthy and costly tr
Externí odkaz:
https://doaj.org/article/7e23c90cbbce47e48a5cc633e7f57b99
Autor:
Custódia Fonseca, Manuel Aureliano
Publikováno v:
BioChem, Vol 2, Iss 2, Pp 145-159 (2022)
In this contribution, we provide an overview of gold compound applications against viruses or parasites during recent years. The special properties of gold have been the subject of intense investigation in recent years, which has led to the developme
Externí odkaz:
https://doaj.org/article/5ebfcd1c70064005b6fd3a896778fca3
Publikováno v:
BioImpacts, Vol 10, Iss 2, Pp 97-104 (2020)
Introduction: Drug-drug interactions (DDIs) are the main causes of the adverse drug reactions and the nature of the functional and molecular complexity of drugs behavior in the human body make DDIs hard to prevent and threat. With the aid of new tech
Externí odkaz:
https://doaj.org/article/9781252ddb11495daa82d6dcc1bfe027
Autor:
Li Zinan
Publikováno v:
BIO Web of Conferences, Vol 61, p 01029 (2023)
Excipients are inactive substances that are included in pharmaceutical formulations alongside active ingredients. These substances are added to pharmaceutical products for various purposes, including improving stability, enhancing bioavailability, ai
Externí odkaz:
https://doaj.org/article/aa8210b7370a43c5979e013b9c251658
Autor:
Jun-sheng Tian, Hui-liang Zhao, Yao Gao, Qi Wang, Huan Xiang, Xiang-ping Xu, Sheng Huang, Dong-lan Yan, Xue-mei Qin
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Background: Cyclophosphamide is a common tumor chemotherapy drug used to treat various cancers. However, the resulting immunosuppression leads to leukopenia, which is a serious limiting factor in clinical application. Therefore, the introduction of i
Externí odkaz:
https://doaj.org/article/4c694b0987f6457899b2f1963def88cd
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 44-50 (2019)
This study reports the application of inverse virtual screening (iVS) methodologies to identify cellular proteins as suitable targets for a library of heterocyclic small-molecules, with potential pharmacological implications. Standard synthetic proce
Externí odkaz:
https://doaj.org/article/7f40673e7dfb42fb8b8ad9670c7d247e
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