Zobrazeno 1 - 10
of 229
pro vyhledávání: '"biological sciences research methodologies"'
Autor:
Yuxiang Hu, Ziqi He, Shuangai Liu, Wenwen Ying, Yifan Chen, Manli Zhao, Min He, Xuan Wu, Yinbing Tang, Weizhong Gu, Meidan Ying, Jinhu Wang, Ting Tao
Publikováno v:
iScience, Vol 27, Iss 10, Pp 110862- (2024)
Summary: Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in childhood and adolescence. The availability of appropriate and well-characterized preclinical models for RMS is limited, posing a challenge for investigating the molecular mech
Externí odkaz:
https://doaj.org/article/571bb153e6304b0cb9a29265bd36f474
Autor:
Bryan Labra, Kshitij Parag-Sharma, John J. Powers, Sonal Srivastava, Joel R. Walker, Thomas A. Kirkland, Caroline K. Brennan, Jennifer A. Prescher, Antonio L. Amelio
Publikováno v:
iScience, Vol 27, Iss 9, Pp 110655- (2024)
Summary: The ability to visualize and track multiple biological processes in vivo in real time is highly desirable. Bioluminescence imaging (BLI) has emerged as an attractive modality for non-invasive cell tracking, with various luciferase reporters
Externí odkaz:
https://doaj.org/article/8200a627020a4d0fa1f45a1065516ab8
Autor:
Peng Deng, Shoupei Liu, Yaoguang Zhao, Xinxin Zhang, Yufei Kong, Linlin Liu, Yujie Xiao, Shasha Yang, Jiahao Hu, Jixiong Su, Ang Xuan, Jinhong Xu, Huijuan Li, Xiaoman Su, Jingchuan Wu, Yuli Jiang, Yu Mu, Zhicheng Shao, Cihang Kong, Bo Li
Publikováno v:
iScience, Vol 27, Iss 8, Pp 110554- (2024)
Summary: Zebrafish and organoids, crucial for complex biological studies, necessitate an imaging system with deep tissue penetration, sample protection from environmental interference, and ample operational space. Traditional three-photon microscopy
Externí odkaz:
https://doaj.org/article/47bdc7746ed8453392e44b027800a38f
Autor:
Shimoya, Kazuto 1, Moriwaki, Takashi 2, 3, Kazuki, Kanako 2, Okada, Akane 2, Baba, Shigenori 3, Masuda, Yuana 3, Abe, Satoshi 2, ∗, Kazuki, Yasuhiro 1, 2, 3, 4, 5, ∗∗
Publikováno v:
In iScience 20 December 2024 27(12)
Publikováno v:
In iScience 15 November 2024 27(11)
Autor:
Olivia Wegrzyniak, Francesco Lechi, Bogdan Mitran, Pierre Cheung, Athanasios Bitzios, Jonas Persson, John Löfblom, Helena Nordström, Jonas Eriksson, Fredrik Y. Frejd, Olle Korsgren, Bo Zhang, Olof Eriksson
Publikováno v:
iScience, Vol 27, Iss 5, Pp 109688- (2024)
Summary: Non-invasive assessment of fibrogenic activity, rather than fibrotic scars, could significantly improve the management of fibrotic diseases and the development of anti-fibrotic drugs. This study explores the potential of an Affibody molecule
Externí odkaz:
https://doaj.org/article/fad25e6180594e048184d89a8e877f10
Autor:
Alessandro Alvaro, Aurora Piazza, Stella Papaleo, Matteo Perini, Ajay Ratan Pasala, Simona Panelli, Tiago Nardi, Riccardo Nodari, Lodovico Sterzi, Cristina Pagani, Cristina Merla, Daniele Castelli, Emanuela Olivieri, Silvia Bracco, Maria Laura Ferrando, Francesca Saluzzo, Sara Giordana Rimoldi, Marta Corbella, Annalisa Cavallero, Paola Prati, Claudio Farina, Daniela Maria Cirillo, Gianvincenzo Zuccotti, Francesco Comandatore
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109402- (2024)
Summary: Serratia marcescens is an opportunistic pathogen that survives in inhospitable environments causing large outbreaks, particularly in neonatal intensive care units (NICUs). Genomic studies revealed that most S. marcescens nosocomial infection
Externí odkaz:
https://doaj.org/article/a0c1c69f624546848928aab0d4bae34f
Autor:
Daniel Rüdiger, Julita Piasecka, Jan Küchler, Carolina Pontes, Tanja Laske, Sascha Y. Kupke, Udo Reichl
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109421- (2024)
Summary: Defective interfering particles (DIPs) are regarded as potent broad-spectrum antivirals. We developed a mathematical model that describes intracellular co-infection dynamics of influenza standard virus (STV) and “OP7”, a new type of infl
Externí odkaz:
https://doaj.org/article/f017adf2437f4bf8a8847f4a5920e2df
Autor:
Collyn M. Kellogg, Kevin Pham, Sunghwan Ko, Jillian E.J. Cox, Adeline H. Machalinski, Michael B. Stout, Amanda L. Sharpe, Michael J. Beckstead, Ana J. Chucair-Elliott, Sarah R. Ocañas, Willard M. Freeman
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108413- (2023)
Summary: Temporally controlling Cre recombination through tamoxifen (Tam) induction has many advantages for biomedical research. Most studies report early post-natal/juvenile (12 m.o.). While anecdotally reported as problematic, there are no publishe
Externí odkaz:
https://doaj.org/article/efa2f29c8faf4f80b3c9fffa0d593cbf
Publikováno v:
iScience, Vol 26, Iss 11, Pp 108111- (2023)
Summary: RNA-binding protein with multiple splicing (RBPMS) plays a crucial role in cardiac mesoderm specification and cardiovascular development, as well as being a typical marker for whole retinal ganglion cells (RGCs). However, there is a lack of
Externí odkaz:
https://doaj.org/article/c165d89d517940499ce3e24d4497ad3e