Zobrazeno 1 - 10
of 35 031
pro vyhledávání: '"biological evaluation"'
Autor:
Muhammad Akash, Nehal Rana, Sana Aslam, Matloob Ahmad, Muhammad Jawwad Saif, Aneeza Asghar, Sadia Sultan, Sami A. Al-Hussain, Afifa Liaqat, Sumera Zaib, Magdi E. A. Zaki
Publikováno v:
Frontiers in Chemistry, Vol 12 (2024)
The urease enzyme is recognized as a valuable therapeutic agent for treating the virulent Helicobacter pylori bacterium because of its pivotal role in aiding the colonization and growth of the bacterium within the gastric mucosa. In order to control
Externí odkaz:
https://doaj.org/article/054312871d3544099ec26f419e18d35e
Publikováno v:
Shipin gongye ke-ji, Vol 44, Iss 24, Pp 341-348 (2023)
A functional compound selenium-enriched plant solid beverage was successfully developed by taking the selenium-enriched medicinal and edible plants Brassica oleracea, Pueraria lobata, Ampelopsis grossedentata, Polygonatum sibiricum, Chaenomeles sinen
Externí odkaz:
https://doaj.org/article/041619c0d8454df99c5555570ef6e461
Autor:
Desimir Luković, Andjela A. Franich, Marija D. Živković, Snežana Rajković, Bojan Stojanović, Nevena Gajović, Milena Jurišević, Slađana Pavlović, Bojana Simović Marković, Marina Jovanović, Bojana S. Stojanović, Radiša Pavlović, Ivan Jovanović
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 15, p 8525 (2024)
The history of effective anti-cancer medications begins with the discovery of cisplatin’s anti-cancer properties. Second-generation analogue, carboplatin, with a similar range of effectiveness, made progress in improving these drugs with fewer side
Externí odkaz:
https://doaj.org/article/a80d3530ccad454dae8c32a8cbc37b07
Autor:
Xuemei Xu, Zhaojingtao Zhu, Siyu Chen, Yanneng Fu, Jinxia Zhang, Yangyang Guo, Zhouyang Xu, Yingying Xi, Xuebao Wang, Faqing Ye, Huijun Chen, Xiaojiao Yang
Publikováno v:
Frontiers in Chemistry, Vol 12 (2024)
Introduction: Cancer, a significant global health concern, necessitates innovative treatments. The pivotal role of chronic inflammation in cancer development underscores the urgency for novel therapeutic strategies. Benzothiazole derivatives exhibit
Externí odkaz:
https://doaj.org/article/1e0ac4b0f9b84e48a04664449feaf1a2
Autor:
Sadeq M. AlHazmy, Mohamed Oussama Zouaghi, Ahmed N. Al-Hakimi, Thamer Alorini, Ibrahim A. Alhagri, Youssef Arfaoui, Rania Al-Ashwal, Lamjed Mansour, Naceur Hamdi
Publikováno v:
Heliyon, Vol 10, Iss 5, Pp e26349- (2024)
A new Schiff base, 1-(E)-(4-((E) 4nitrobenzylidene) amino) phenyl)imino) methyl)naphthalen-2-ol (4NMN), was prepared from the reaction of p-phenylenediamine with 2-hydroxy-1-naphthaldehyde and 4-nitrobenzaldehyde and characterized with spectroscopic
Externí odkaz:
https://doaj.org/article/4c607e31b9b546018a580bb11f47fdd4
Autor:
Israa Habeeb Naser, Hassan Thoulfikar A. Alamir, Ali Hisham Al-Shukarji, Batool Ali Ahmed, Talal Aziz Qassem, Maher Kamal, Tahani M. Almeleebia, Enas R. Alwaily, Eftikhaar Hasan Kadhum, Ahmed Alawadi, Ali Alsalamy
Publikováno v:
Frontiers in Chemistry, Vol 12 (2024)
In this study, choline chloride/urea was used as a green deep eutectic solvent in the three-component reaction of hydrazine/phenylhydrazine, malononitrile, and aromatic aldehydes for synthesizing pyrazole derivatives, and in the four-component reacti
Externí odkaz:
https://doaj.org/article/599559d9eed545078ea937e1891658af
Publikováno v:
Frontiers in Natural Products, Vol 2 (2024)
Externí odkaz:
https://doaj.org/article/d2c328accdc74d30aa76b8bec39bc94e
Autor:
Gonca Çelik, Hüseyin Şahin, Nimet Baltaş, Nevzat Batan, Şengül Alpay Karaoğlu, Nurettin Yayli
Publikováno v:
Botanica Serbica, Vol 47, Iss 1, Pp 31-40 (2023)
The aim of this study was to investigate the chemical composition of the essential oils (EOs) from two Diplophyllum species and to evaluate their bioactivity potential [antimicrobial, antioxidant, anti-urease, anti-xanthine oxidase (XO)], and pheno
Externí odkaz:
https://doaj.org/article/62e44e3158144b5ab7904195cb5300a0
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
As part of our continuous efforts to discover novel c-Met inhibitors as antitumor agents, four series of thiazole/thiadiazole carboxamide-derived analogues were designed, synthesised, and evaluated for the in vitro activity against c-Met and four hum
Externí odkaz:
https://doaj.org/article/4b8485749a9a42e9bcaf53a972b81234
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
Heat shock protein 90 (Hsp90) is considered an attractive therapeutic target for cancer treatment due to its high expression in many cancers. In this study, four potent Hsp90 inhibitors (HPs 1–4) were identified using structure-based virtual screen
Externí odkaz:
https://doaj.org/article/7504d5796a3d40b9b39d3e81bc3cd7d7