Zobrazeno 1 - 10
of 1 811
pro vyhledávání: '"bioinformatica"'
Autor:
Rik L. de Swart, Olav S. de Leeuw, Nadia Oreshkova, Nora M. Gerhards, Irina C. Albulescu, Sandra Vreman, José L. Gonzales, Riks Maas, Frank J.M. van Kuppeveld, Peter Soema, Berend-Jan Bosch, Ben P.H. Peeters
Publikováno v:
Vaccine 40 (2022) 33
Vaccine, 40(33), 4676-4681
Vaccine, 40(33), 4676-4681
The emergence of SARS-CoV-2 in December 2019 resulted in the COVID-19 pandemic. Recurring disease outbreaks repeatedly overloaded the public health sector and severely affected the global economy. We developed a candidate COVID-19 vaccine based on a
Autor:
Niek F. de Jonge, Joris J. R. Louwen, Elena Chekmeneva, Stephane Camuzeaux, Femke J. Vermeir, Robert S. Jansen, Florian Huber, Justin J. J. van der Hooft
Publikováno v:
Nature Communications, 14, 1-12
Nature Communications, 14, 1, pp. 1-12
Nature Communications, 14(1)
Nature Communications 14 (2023) 1
Nature Communications, 14, 1, pp. 1-12
Nature Communications, 14(1)
Nature Communications 14 (2023) 1
Metabolomics-driven discoveries of biological samples remain hampered by the grand challenge of metabolite annotation and identification. Only few metabolites have an annotated spectrum in spectral libraries; hence, searching only for exact library m
Autor:
Karol Al Ayed, Denise Zamarbide Losada, Nataliia V. Machushynets, Barbara Terlouw, Somayah S. Elsayed, Julian Schill, Vincent Trebosc, Michel Pieren, Marnix H. Medema, Gilles P. van Wezel, Nathaniel I. Martin
Publikováno v:
ACS Infectious Diseases 9 (2023) 4
ACS Infectious Diseases, 9(4), 739-748
ACS Infectious Diseases, 9(4), 739-748
The unabated rise of antibiotic resistance has raised the specter of a post-antibiotic era and underscored the importance of developing new classes of antibiotics. The relacidines are a recently discovered group of nonribosomal lipopeptide antibiotic
Publikováno v:
Trends in Genetics, 39(4), 237-239
Trends in Genetics 39 (2023) 4
Trends in Genetics 39 (2023) 4
Convergent evolution has been described for several metabolic pathways across the kingdoms of life. However, there is hitherto no evidence for such an interkingdom process for antimicrobials. A new report suggests that marine animals have evolved the
Autor:
Chen, Lianmin, Zhernakova, Daria V., Kurilshikov, Alexander, Andreu-Sánchez, Sergio, Wang, Daoming, Augustijn, Hannah E., Vich Vila, Arnau, Weersma, Rinse K., Medema, Marnix H., Netea, Mihai G., Kuipers, Folkert, Wijmenga, Cisca, Zhernakova, Alexandra, Fu, Jingyuan
Publikováno v:
Nature Medicine, 28. Nature Publishing Group
Nature Medicine 28 (2022) 11
Nature Medicine, 28(11), 2333-2343
Nature Medicine, 28, 2333-2343
Nature Medicine, 28, 11, pp. 2333-2343
Nature Medicine 28 (2022) 11
Nature Medicine, 28(11), 2333-2343
Nature Medicine, 28, 2333-2343
Nature Medicine, 28, 11, pp. 2333-2343
Contains fulltext : 286883.pdf (Publisher’s version ) (Open Access) The levels of the thousands of metabolites in the human plasma metabolome are strongly influenced by an individual's genetics and the composition of their diet and gut microbiome.
Autor:
Yanting Wang, Janani Durairaj, Hernando G. Suárez Duran, Robin van Velzen, Kristyna Flokova, Che‐Yang Liao, Aleksandra Chojnacka, Stuart MacFarlane, M. Eric Schranz, Marnix H. Medema, Aalt D. J. van Dijk, Lemeng Dong, Harro J. Bouwmeester
Publikováno v:
New Phytologist, 235(5), 1884-1899. Wiley-Blackwell
New Phytologist, 235(5), 1884-1899
New Phytologist 235 (2022) 5
New Phytologist, 235(5), 1884-1899
New Phytologist 235 (2022) 5
Strigolactones (SLs) are rhizosphere signalling molecules and phytohormones. The biosynthetic pathway of SLs in tomato has been partially elucidated, but the structural diversity in tomato SLs predicts that additional biosynthetic steps are required.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b02207b2f58c04b3b465155c30af9d1
https://dare.uva.nl/personal/pure/en/publications/the-tomato-cytochrome-p450-cyp712g1-catalyzes-the-double-oxidation-of-orobanchol-en-route-to-the-rhizosphere-signaling-strigolactone-solanacol(055442e2-0845-4490-b694-ce92bcfca475).html
https://dare.uva.nl/personal/pure/en/publications/the-tomato-cytochrome-p450-cyp712g1-catalyzes-the-double-oxidation-of-orobanchol-en-route-to-the-rhizosphere-signaling-strigolactone-solanacol(055442e2-0845-4490-b694-ce92bcfca475).html
Autor:
Li, Bohui
In chapter one, a general introduction to the basic principles and techniques of MS-based proteomics, quantification strategies, and a generalized shotgun proteomics workflow are given. Moreover, I also outline how to analyze proteomics data from a b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______101::2c0bcde1803eb3dfc94ed5dceba74e88
https://dspace.library.uu.nl/handle/1874/428709
https://dspace.library.uu.nl/handle/1874/428709
Autor:
Timothy M.D. Ebbels, Justin J.J. van der Hooft, Haley Chatelaine, Corey Broeckling, Nicola Zamboni, Soha Hassoun, Ewy A. Mathé
Publikováno v:
Current Opinion in Chemical Biology, 74
Current Opinion in Chemical Biology 74 (2023)
Current Opinion in Chemical Biology 74 (2023)
The computational metabolomics field brings together computer scientists, bioinformaticians, chemists, clinicians, and biologists to maximize the impact of metabolomics across a wide array of scientific and medical disciplines. The field continues to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2e9f678ae3fdc79693477ee70f72f09
https://hdl.handle.net/20.500.11850/607327
https://hdl.handle.net/20.500.11850/607327
In this thesis we have studied the molecular characteristics of various types of non-Hodgkin lymphoma with the aim to advance our understanding of its biology and improve classification and disease diagnosis. For this, we have collected several lymph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______4612::40d0d9b591d7461824e35bd3dcfe8064
https://research.vu.nl/en/publications/3f1c057f-5a40-4811-9140-977885fc9a0f
https://research.vu.nl/en/publications/3f1c057f-5a40-4811-9140-977885fc9a0f