Zobrazeno 1 - 10
of 1 103
pro vyhledávání: '"bioanalytical method"'
Autor:
Lucas F. F. Albuquerque, Maria Victoria Souto, Felipe Saldanha-Araujo, Juliana Lott Carvalho, Tais Gratieri, Marcilio Cunha-Filho, Guilherme M. Gelfuso
Publikováno v:
Chemistry, Vol 6, Iss 2, Pp 272-282 (2024)
Ibrutinib (IBR) is a tyrosine kinase inhibitor investigated for treating solid and non-solid tumors. Considering the advantages that a topical application of IBR could generate in terms of dose reduction and side effects in skin cancer treatment, thi
Externí odkaz:
https://doaj.org/article/401779a63ef64831b15ea74756506a39
Autor:
Eunseo Song, Wang-Seob Shim, Doowon Choi, Yuna Song, Hyeong Geun Jo, Soobok Lee, Suk Han Jung, Yeo Jin Choi, Kyung-Tae Lee
Publikováno v:
Molecules, Vol 29, Iss 18, p 4505 (2024)
A highly accurate, precise, and simple liquid chromatography-tandem mass spectrometry (LC–MS/MS) method for ketotifen (KTF) estimation from Beagle dog plasma was developed and validated, with ketotifen-d3 (KTF-d3) as the internal standard (IS). KTF
Externí odkaz:
https://doaj.org/article/8b2c3278891b41dfa2859d00463b4c6c
Publikováno v:
Cellular, Molecular and Biomedical Reports, Vol 5, Iss 1, Pp 48-62 (2025)
Monoclonal antibodies (mAbs) represent a cornerstone of modern therapeutic strategies, targeting a wide array of diseases with unprecedented specificity. Developing and validating bioanalytical methods for mAbs are critical to ensuring their efficacy
Externí odkaz:
https://doaj.org/article/eb0bff815d6f4f6fa021e24a3772ca3b
Autor:
Valdeene Vieira Santos, Matheus Antônio da Hora Borges, Karoline Cristina Jatobá da Silva, Rafael dos Santos Costa, Renan Fernandes do Espírito Santo, Eudes da Silva Velozo, Cristiane Flora Villarreal, Francine Johansson Azeredo
Publikováno v:
Pharmaceutics, Vol 16, Iss 6, p 714 (2024)
The compound 6-methoxyseselin, derived from Zanthoxylum tingoassuiba, demonstrates various therapeutic properties, including vasorelaxation, antinociceptive, anti-inflammatory, and immunomodulatory effects, along with recently discovered antiasthmati
Externí odkaz:
https://doaj.org/article/c3136791e07d44c48ef3327aaa6fbeda
Autor:
Ramakrishna Nirogi, Ilayaraja Kalaikadhiban, Lakshmi Prasanna Rayapati, Hanumanth Rao Pantangi, Prathyusha Chunduru, Satish Jetta, Avinash Jubre, Abdul Rasheed Mohammed
Publikováno v:
Journal of Chromatography Open, Vol 3, Iss , Pp 100073- (2023)
SUVN-911 (Ropanicant) is a novel alpha-4 beta-2 nicotinic acetylcholine receptor (α4β2 nAChR) antagonist being developed for the treatment of major depressive disorders (MDD). An Ultra high-performance liquid chromatography-tandem mass spectrometry
Externí odkaz:
https://doaj.org/article/ea9e09b796bd4eacb6f7dfaae3a236aa
Autor:
Norisca Aliza Putriana, Taofik Rusdiana, Nurhanifah Puspitadewi, Driyanti Rahayu, Febrina Amelia Saputri
Publikováno v:
Journal of Advanced Pharmaceutical Technology & Research, Vol 14, Iss 4, Pp 345-350 (2023)
Vitamin K can reduce warfarin's anticoagulant action, causing a variance in response among individuals taking warfarin. Vitamin K comes in two forms, namely Vitamin K1 (phylloquinone) and K2 (menaquinones). Menaquinone-4 (MK-4) is a kind of Vitamin K
Externí odkaz:
https://doaj.org/article/5dc97c8c8c1e4c0181b7e5fb0bfe0d8f
Autor:
Khaled Shalaby, Saleh Alghamdi, Mohammed Gamal, Lobna Mohammed Abd Elhalim, Rehab Moussa Tony
Publikováno v:
BMC Chemistry, Vol 16, Iss 1, Pp 1-13 (2022)
Abstract Cabergoline (CAB) is effective prolactin lowering drug. Evaluation of the bioequivalence for the new test product (0.5 mg CAB film-coated tablets) in Egypt is strongly needed for approval of the drug by the official health authority. Therefo
Externí odkaz:
https://doaj.org/article/342b9579a7ac4bb894cf74c39094d789
Autor:
Daniela Milosheska, Robert Roškar
Publikováno v:
Molecules, Vol 28, Iss 23, p 7830 (2023)
The objective of the present report was to develop and validate a simple, selective, and reproducible high-performance liquid chromatography method with UV detection suitable for routine therapeutic drug monitoring of the most commonly used antiepile
Externí odkaz:
https://doaj.org/article/39ba40a729d3498eaf75a60d13a3efe5
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