Oxidative DNA cleavage mediated by a new unexpected [Pd(BAPP)][PdCl4] complex (BAPP = 1,4-bis(3-aminopropyl)piperazine): crystal structure, DNA binding and cytotoxic behavior

Autor: Mona S. Ragab, Mohamed R. Shehata, Mohamed M. Shoukry, Matti Haukka, Mohamed A. Ragheb

Publikováno v: RSC Advances. 12:1871-1884

A novel Pd(II) double complex, [Pd(BAPP)][PdCl4], containing the 1,4-bis(3-aminopropyl)piperazine (BAPP) ligand is investigated. X-ray crystallography of a single crystal confirmed the structure of the [Pd(BAPP)][PdCl4] complex. The spectroscopic beh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b37dc54943f6dbe4c08be307dc150056
https://doi.org/10.1039/d1ra07793g

Crotofolane Diterpenoids and Other Constituents Isolated from Croton kilwae

Autor: Emanuel T. Mahambo, Colores Uwamariya, Masum Miah, Leandro da Costa Clementino, Luis Carlos Salazar Alvarez, Gabriela Paula Di Santo Meztler, Edward Trybala, Joanna Said, Lianne H. E. Wieske, Jas S. Ward, Kari Rissanen, Joan J. E. Munissi, Fabio T. M. Costa, Per Sunnerhagen, Tomas Bergström, Stephen S. Nyandoro, Mate Erdelyi

Six new crotofolane diterpenoids (1-6) and 13 known compounds (7-19) were isolated from the MeOH- CH2Cl2 (1:1, v/v) extracts of the leaves and stem bark of Croton kilwae. The structures of the new compounds were elucidated by extensive analysis of sp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3fe135bfd04af1a4a41222f99c12246
http://urn.fi/URN:NBN:fi:jyu-202302091700

Efficient Consecutive Synthesis of Ethyl-2-(4-Aminophenoxy) Acetate, a Precursor for Dual GK and PPARγ Activators, X-ray Structure, Hirshfeld Analysis, and DFT Studies

Autor: Altowyan, Mezna Saleh, Soliman, Saied M., Ismail, Magda M. F., Haukka, Matti, Barakat, Assem, Ayoup, Mohammed Salah

Herein, we report a facile synthesis of ethyl-2-(4-aminophenoxy)acetate 4 as a building synthon for novel dual hypoglycemic agents. This building template was synthesized by alkylation of 4-nitrophenol with ethyl bromo-acetate followed by selective r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1222::1687a00ba2d5c30fbf0293fb7d5ea09e
http://urn.fi/URN:NBN:fi:jyu-202203031772

Synthesis, X-ray Single-Crystal Analysis, and Anticancer Activity Evaluation of New Alkylsulfanyl-Pyridazino[4,5-b]indole Compounds as Multitarget Inhibitors of EGFR and Its Downstream PI3K-AKT Pathway

Autor: Eid E. Salama, Ibrahim O. Althobaiti, Matti Haukka, Ahmed T. A. Boraei

Publikováno v: Crystals; Volume 12; Issue 3; Pages: 353

The alkylation of 3,5-dihydro-4H-pyridazino[4,5-b]indole-4-thione with benzyl bromide, ethyl chloroacetate, and allyl bromide in the presence of potassium carbonate (K2CO3) yielded new alkylsulfanylpyridazino[4,5-b]indole derivatives (i.e., compounds

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcfcc9034d187a441ad08337dda8a19a
http://urn.fi/URN:NBN:fi:jyu-202203161885

Water soluble organometallic small molecules as promising antibacterial agents: synthesis, physical-chemical properties and biological evaluation to tackle bacterial infections

Autor: Ines Bennour, M. Núria Ramos, Miquel Nuez-Martínez, Jewel Ann Maria Xavier, Ana B. Buades, Reijo Sillanpää, Francesc Teixidor, Duane Choquesillo-Lazarte, Isabel Romero, Margarita Martinez-Medina, Clara Viñas

Publikováno v: Dalton Transactions, 2022, vol. 51, núm. 18, p. 7188-7209
Articles publicats (D-Q)
DUGiDocs – Universitat de Girona
instname
Digibug. Repositorio Institucional de la Universidad de Granada
Digital.CSIC. Repositorio Institucional del CSIC

This work was supported by the Spanish Ministerio de Economia y Competitividad (PID2019-106832RB-100, and SAF2017-82261-P grant cofounded by the European Regional Development Fund) and the Generalitat de Catalunya (2017SGR1720). J. A. M. Xavier ackno

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93a4917303183d9c1a27c253577252af
http://hdl.handle.net/10256/21795