Zobrazeno 1 - 10
of 1 006
pro vyhledávání: '"bile salt export pump"'
Autor:
Qiong Pan, Gang Luo, Jiaquan Qu, Sheng Chen, Xiaoxun Zhang, Nan Zhao, Jingjing Ding, Hong Yang, Mingqiao Li, Ling Li, Ying Cheng, Xuan Li, Qiaoling Xie, Qiao Li, Xueqian Zhou, Huiling Zou, Shijun Fan, Lingyun Zou, Wei Liu, Guohong Deng, Shi‐Ying Cai, James L Boyer, Jin Chai
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 11, Pp 1-11 (2021)
Abstract Semaphorin 7A (SEMA7A) is a membrane‐bound protein that involves axon growth and other biological processes. SEMA7A mutations are associated with vertebral fracture and Kallmann syndrome. Here, we report a case with a mutation in SEMA7A th
Externí odkaz:
https://doaj.org/article/566f092f5c7547c2ae4b6f215821f301
Autor:
Shang-Hsin Wu, Mei-Hwei Chang, Ya-Hui Chen, Hui-Lin Wu, Huey-Huey Chua, Chin-Sung Chien, Yen-Hsuan Ni, Hui-Ling Chen, Huey-Ling Chen
Publikováno v:
Journal of Biomedical Science, Vol 28, Iss 1, Pp 1-18 (2021)
Abstract Background The bile salt export pump (BSEP) is a pivotal apical/canalicular bile salt transporter in hepatocytes that drives the bile flow. Defects in BSEP function and canalicular expression could lead to a spectrum of cholestatic liver dis
Externí odkaz:
https://doaj.org/article/b09117dbbc004da487680ebecda8e920
Progressive familial CD10 deficient ductopenic disorder; Hitherto an unnamed entity! - A case report
Publikováno v:
Indian Journal of Transplantation, Vol 15, Iss 2, Pp 176-180 (2021)
Inherited liver disorders are group of genetic diseases that cause early liver involvement many of them progressing to early cirrhosis. Of the familial cholestatic disorders most widely studied are progressive familial intrahepatic cholestatic disord
Externí odkaz:
https://doaj.org/article/113d023a2d374b7ea93833f4f72297ab
Akademický článek
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Progressive Familial Intrahepatic Cholestasis in Korea: A Clinicopathological Study of Five Patients
Autor:
Hyo Jeong Kang, Soon Auck Hong, Seak Hee Oh, Kyung Mo Kim, Han-Wook Yoo, Gu-Hwan Kim, Eunsil Yu
Publikováno v:
Journal of Pathology and Translational Medicine, Vol 53, Iss 4, Pp 253-260 (2019)
Background Progressive familial intrahepatic cholestasis (PFIC) is a heterogeneous group of autosomal recessive liver diseases that present as neonatal cholestasis. Little is known of this disease in Korea. Methods The records of five patients histol
Externí odkaz:
https://doaj.org/article/a48829eb48044cc88e81146b6c4fde1d
Akademický článek
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Autor:
Jack Uetrecht
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
The idiosyncratic nature of idiosyncratic drug-induced liver injury (IDILI) makes mechanistic studies very difficult, and little is known with certainty. However, the fact that the IDILI caused by some drugs is associated with specific HLA genotypes
Externí odkaz:
https://doaj.org/article/f184cbe21f31432b8e6528a0c410ad98
Autor:
Xiao-Li Xiong, Yan Ding, Zhi-Lin Chen, Yao Wang, Pan Liu, Huan Qin, Li-Shan Zhou, Ling-Ling Zhang, Juan Huang, Lei Zhao
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
AimBile salt export pump (BSEP) have been confirmed to play an important role for bile acid canalicular export in the treatment of cholestasis. In this study, we investigated the stimulatory effect of emodin on BSEP signaling pathway in cholestasis.M
Externí odkaz:
https://doaj.org/article/073f56413a4a4eba82042462fe0badbf
Autor:
Joanna Pawłowska, A S Knisely, Pamela Parsons, Milton J. Finegold, Piotr Czubkowski, Richard J. Thompson, Sandra Strautnieks, Joanna Cielecka-Kuszyk, Irena Jankowska, Laura N. Bull
Publikováno v:
World Journal of Clinical Cases
BACKGROUND Functioning farnesoid X receptor (FXR; encoded by NR1H4) is key to normal bile acid homeostasis. Biallelic mutations in NR1H4 are reported in a few children with intrahepatic cholestasis. We describe a boy with progressive familial intrahe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88a2053a427bdc8a65e253a45cb5d875
http://europepmc.org/articles/PMC8130085
http://europepmc.org/articles/PMC8130085
Akademický článek
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