Zobrazeno 1 - 10
of 325
pro vyhledávání: '"bicyclol"'
Autor:
Tong-Tong Liu, Hai-Fei Sun, Ming-Ze Tang, Hao-Ran Shen, Zhen Shen, Yan-Xing Han, Yun Zhan, Jian-Dong Jiang
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Background Silicosis is an irreversible fibrotic disease of the lung caused by chronic exposure to silica dust, which manifests as infiltration of inflammatory cells, excessive secretion of pro-inflammatory cytokines, and pulmonary diffuse f
Externí odkaz:
https://doaj.org/article/2b118b10efc04e819d2449e7e07a98e0
Publikováno v:
Chinese Medicine, Vol 19, Iss 1, Pp 1-26 (2024)
Abstract Cancer remains one of the leading causes of mortality worldwide. The search for novel and effective anticancer agents has been a significant area of research. Dibenzocyclooctadiene lignans (DBCLS), derived from the Schisandra genus plants li
Externí odkaz:
https://doaj.org/article/9cbb588993d24cd99b20377ba8463caf
Autor:
К.М. Usychenko
Publikováno v:
Medičnì Perspektivi, Vol 28, Iss 3, Pp 45-54 (2023)
According to recent WHO estimates, chronic HBV infection is one of the leading causes of death and disability in patients with infectious diseases. From 780 thousand to 1 million deaths are annually recorded in the world as a result of cirrhosis of t
Externí odkaz:
https://doaj.org/article/304b576af6de457fa344eecb14e8a991
Autor:
K.M. Usychenko
Publikováno v:
Клінічна та профілактична медицина, Iss 3, Pp 45-51 (2023)
Modern antiviral therapy regimens for patients with chronic viral hepatitis aim to achieve either long-term suppression of pathogen replication (e.g., nucleoside analogs in chronic hepatitis B) or complete elimination of the virus (such as direct-act
Externí odkaz:
https://doaj.org/article/e954797992cf482c9100cda64426f583
Autor:
Xucong Huang, Zhenghua Wu, Yanchao Liu, Mengqi Jia, Wenjuan Zhao, Shuowen Wang, Xinhui Jiang, Yuefen Lou, Guorong Fan
Publikováno v:
Arabian Journal of Chemistry, Vol 16, Iss 12, Pp 105287- (2023)
A simple, sensitive, and rapid LC-MS/MS method for the simultaneous determination of BIC, the M7 and M8 active metabolites in SD rat plasma was developed. After salting-out assisted liquid–liquid extraction (SALLE) with 5 M ammonium acetate solutio
Externí odkaz:
https://doaj.org/article/ae5580ebca0c4e90b78c312ffa9af1f1
Autor:
Jing Jiang, Hu Li, Mei Tang, Lei Lei, Hong-Ying Li, Biao Dong, Jian-Rui Li, Xue-Kai Wang, Han Sun, Jia-Yu Li, Jing-Chen Xu, Yue Gong, Jian-Dong Jiang, Zong-Gen Peng
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 10, p 5086 (2024)
Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most common metabolic disease of the liver, characterized by hepatic steatosis in more than 5% of hepatocytes. However, despite the recent approval of the first drug, resmetirom,
Externí odkaz:
https://doaj.org/article/ef4cc191055d4894816d86198351a93a
Akademický článek
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Autor:
Xucong Huang, Zhenghua Wu, Xijier Qiaolongbatu, Han Qu, Cui Ma, Yujie Xiang, Mengqi Jia, Yanchao Liu, Shuowen Wang, Lili Jing, Xinhui Jiang, Yuefen Lou, Guorong Fan
Publikováno v:
Arabian Journal of Chemistry, Vol 16, Iss 10, Pp 105107- (2023)
In our previous study, several bicyclol (BIC) metabolites were found to possess higher solubility, security, and efficacy than the parent drug. However, further research can’t be conducted without monomeric metabolites. In the current study, a high
Externí odkaz:
https://doaj.org/article/6115976574f9423e8b8ec3cbd3429480
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
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Autor:
Frontiers Production Office
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/40ebb35076034ff1b3766d842f764e52