Point mutations affecting yeast prion propagation change the structure of its amyloid fibrils

Autor: Mikhail V. Belousov, Irina M. Kuznetsova, Nina P. Trubitsina, Anna I. Sulatskaya, Galina A. Zhouravleva, Maksim I. Sulatsky, Konstantin K. Turoverov, Manuel A. Llanos, Stanislav A. Bondarev, Andrey V. Kajava

Publikováno v: Journal of Molecular Liquids
Journal of Molecular Liquids, Elsevier, 2020, 314, pp.113618. ⟨10.1016/j.molliq.2020.113618⟩
SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP

We investigated the effect of the point substitutions in the N-terminal domain of the yeast prion protein Sup35 (Sup35NMp) on the structure of its amyloid fibrils. As the objects of the study, proteins with mutations that have different influence on

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1efef5b42e593965472eb28d8ce04d82
https://doi.org/10.1016/j.molliq.2020.113618