Zobrazeno 1 - 10
of 25
pro vyhledávání: '"beta-amyloid aggregation inhibitors"'
Autor:
Raluca Stefanescu, Gabriela Dumitriṭa Stanciu, Andrei Luca, Luminita Paduraru, Bogdan-Ionel Tamba
Publikováno v:
Biomolecules, Vol 10, Iss 6, p 870 (2020)
Alzheimer’s disease is a neurodegenerative disorder for which there is a continuous search of drugs able to reduce or stop the cognitive decline. Beta-amyloid peptides are composed of 40 and 42 amino acids and are considered a major cause of neuron
Externí odkaz:
https://doaj.org/article/0f5d8305fe2c439ab3258c427ff1e1c7
Autor:
Rosa Purgatorio, Modesto de Candia, Annalisa De Palma, Francesco De Santis, Leonardo Pisani, Francesco Campagna, Saverio Cellamare, Cosimo Damiano Altomare, Marco Catto
Publikováno v:
Molecules, Vol 23, Iss 7, p 1544 (2018)
Despite the controversial outcomes of clinical trials executed so far, the prevention of β-amyloid (Aβ) deposition and neurotoxicity by small molecule inhibitors of Aβ aggregation remains a target intensively pursued in the search of effective dru
Externí odkaz:
https://doaj.org/article/94339352d5fa46c0b2a8512703d69610
Autor:
Sherri C. Young
Publikováno v:
Molecules, Vol 23, Iss 2, p 296 (2018)
Alzheimer’s disease (AD) is an incurable form of dementia affecting millions of people worldwide and costing billions of dollars in health care-related payments, making the discovery of a cure a top health, societal, and economic priority. Peptide-
Externí odkaz:
https://doaj.org/article/ca714c708b7646a8a443199700266475
Autor:
Bogdan-Ionel Tamba, Andrei Luca, Luminita Paduraru, Raluca Stefanescu, Gabriela Dumitriṭa Stanciu
Publikováno v:
Biomolecules, Vol 10, Iss 870, p 870 (2020)
Biomolecules
Biomolecules
Alzheimer’s disease is a neurodegenerative disorder for which there is a continuous search of drugs able to reduce or stop the cognitive decline. Beta-amyloid peptides are composed of 40 and 42 amino acids and are considered a major cause of neuron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ebf256c99a21847c258d1294e66fb8a
https://doi.org/10.3390/biom10060870
https://doi.org/10.3390/biom10060870
Autor:
Angelo De Stradis, Fabio Arnesano, Gerardo Palazzo, Rosa Purgatorio, Francesco Campagna, Marco Catto, Maurizio Losacco, Vincenza Calò
Publikováno v:
Archives of biochemistry and biophysics
560 (2014): 73–82. doi:10.1016/j.abb.2014.07.015
info:cnr-pdr/source/autori:Catto M., Arnesano F., Palazzo G., De Stradis A., Calò V., Losacco M., Purgatorio R., Campagna F./titolo:Investigation on the influence of (Z)-3-(2-(3-chlorophenyl)hydrazono)-5,6-dihydroxyindolin-2-one (PT2) on beta-amyloid(1-40) aggregation and toxicity/doi:10.1016%2Fj.abb.2014.07.015/rivista:Archives of biochemistry and biophysics (Print)/anno:2014/pagina_da:73/pagina_a:82/intervallo_pagine:73–82/volume:560
560 (2014): 73–82. doi:10.1016/j.abb.2014.07.015
info:cnr-pdr/source/autori:Catto M., Arnesano F., Palazzo G., De Stradis A., Calò V., Losacco M., Purgatorio R., Campagna F./titolo:Investigation on the influence of (Z)-3-(2-(3-chlorophenyl)hydrazono)-5,6-dihydroxyindolin-2-one (PT2) on beta-amyloid(1-40) aggregation and toxicity/doi:10.1016%2Fj.abb.2014.07.015/rivista:Archives of biochemistry and biophysics (Print)/anno:2014/pagina_da:73/pagina_a:82/intervallo_pagine:73–82/volume:560
In Alzheimer's disease (AD), native A beta protein monomers aggregate through the formation of a variety of water-soluble, toxic oligomers, ultimately leading to insoluble fibrillar deposits. The inhibition of oligomers formation and/or their dissoci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed83719dc60d07b8239ba4dd4f12d78b
https://doi.org/10.1016/j.abb.2014.07.015
https://doi.org/10.1016/j.abb.2014.07.015
Autor:
Annalisa De Palma, Saverio Cellamare, Leonardo Pisani, Rosa Purgatorio, Cosimo Altomare, Modesto de Candia, Marco Catto, Francesco De Santis, Francesco Campagna
Publikováno v:
Molecules
Volume 23
Issue 7
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules, Vol 23, Iss 7, p 1544 (2018)
Volume 23
Issue 7
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules, Vol 23, Iss 7, p 1544 (2018)
Despite the controversial outcomes of clinical trials executed so far, the prevention of &beta
amyloid (A&beta
) deposition and neurotoxicity by small molecule inhibitors of A&beta
aggregation remains a target intensively pursued in th
amyloid (A&beta
) deposition and neurotoxicity by small molecule inhibitors of A&beta
aggregation remains a target intensively pursued in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9749c73d5e6948a642c069672566b926
https://doi.org/10.3390/molecules23071544
https://doi.org/10.3390/molecules23071544
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