Zobrazeno 1 - 10
of 136
pro vyhledávání: '"beta cell replacement"'
Publikováno v:
Frontiers in Transplantation, Vol 3 (2024)
Externí odkaz:
https://doaj.org/article/aa334fd0466143ebb43cdc37f1dbe476
Publikováno v:
Frontiers in Clinical Diabetes and Healthcare, Vol 5 (2024)
Externí odkaz:
https://doaj.org/article/115a216229334c6db205b5f0d6740e15
Allo Beta Cell transplantation: specific features, unanswered questions, and immunological challenge
Autor:
Rossana Caldara, Valentina Tomajer, Paolo Monti, Valeria Sordi, Antonio Citro, Raniero Chimienti, Chiara Gremizzi, Davide Catarinella, Stefano Tentori, Vera Paloschi, Raffella Melzi, Alessia Mercalli, Rita Nano, Paola Magistretti, Stefano Partelli, Lorenzo Piemonti
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Type 1 diabetes (T1D) presents a persistent medical challenge, demanding innovative strategies for sustained glycemic control and enhanced patient well-being. Beta cells are specialized cells in the pancreas that produce insulin, a hormone that regul
Externí odkaz:
https://doaj.org/article/1fd182f972064ef3a90189fdae70ac20
Autor:
Daniel T. Doherty, Hussein A. Khambalia, David van Dellen, Rachel E. Jennings, Karen Piper Hanley
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Islet transplantation (IT) offers the potential to restore euglycemia for patients with type 1 diabetes mellitus (T1DM). Despite improvements in islet isolation techniques and immunosuppressive regimes, outcomes remain suboptimal with UK five-year gr
Externí odkaz:
https://doaj.org/article/1a007bed63434a25991ca0d05005eda3
Autor:
Gauree S. Chendke, Bhushan N. Kharbikar, Sudipta Ashe, Gaetano Faleo, Julie B. Sneddon, Qizhi Tang, Matthias Hebrok, Tejal A. Desai
Publikováno v:
Bioengineering & Translational Medicine, Vol 8, Iss 4, Pp n/a-n/a (2023)
Abstract Beta cell replacement therapy (BCRT) for patients with type 1 diabetes (T1D) improves blood glucose regulation by replenishing the endogenous beta cells destroyed by autoimmune attack. Several limitations, including immune isolation, prevent
Externí odkaz:
https://doaj.org/article/bdf451e523a94e80a96f8c5a8407ba68
Autor:
Jorge Santini-González, Roberto Castro-Gutierrez, Matthew W. Becker, Chad Rancourt, Holger A. Russ, Edward A. Phelps
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
There is a critical need for therapeutic approaches that combine renewable sources of replacement beta cells with localized immunomodulation to counter recurrence of autoimmunity in type 1 diabetes (T1D). However, there are few examples of animal mod
Externí odkaz:
https://doaj.org/article/3b0ae6ffcae04f0facfe19791550e698
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Type 1 diabetes results from an autoimmune attack directed at pancreatic beta cells predominantly mediated by T cells. Transplantation of stem cell derived beta-like cells (sBC) have been shown to rescue diabetes in preclinical animal models. However
Externí odkaz:
https://doaj.org/article/06fd99859a4448dc9697d80e55dbb658
Akademický článek
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Autor:
Ludwig, Barbara, Ludwig, Stefan, Steffen, Anja, Knauf, Yvonne, Zimerman, Baruch, Heinke, Sophie, Lehmann, Susann, Schubert, Undine, Schmid, Janine, Bleyer, Martina, Schönmann, Uwe, Colton, Clark K., Bonifacio, Ezio, Solimena, Michele, Reichel, Andreas, Schally, Andrew V., Rotem, Avi, Barkai, Uriel, Grinberg-Rashi, Helena, Kaup, Franz-Josef, Avni, Yuval, Jones, Peter, Bornstein, Stefan R.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2017 Oct . 114(44), 11745-11750.
Externí odkaz:
https://www.jstor.org/stable/26488859
Akademický článek
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