Zobrazeno 1 - 10
of 34 762
pro vyhledávání: '"beta cell"'
Autor:
Naeimeh Rezaei, Kianoush Dormiani, Abbas Kiani-Esfahani, Somayeh Mirdamadian, Mohsen Rahmani, Farnoosh Jafarpour, Mohammad Hossein Nasr-Esfahani
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract PDX1 is a crucial transcription factor in pancreas development and mature β-cell function. However, the regulation of PDX1 expression in larger animals mirroring human pancreas morphogenesis and endocrine maturation remains poorly understoo
Externí odkaz:
https://doaj.org/article/f25a74f0e1bc4f98b22f5064fe1b5d33
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-32 (2024)
Abstract Diabetes mellitus (DM), a chronic metabolic disease, poses a significant global health challenge, with current treatments often fail to prevent the long-term disease complications. Mesenchymal stem/stromal cells (MSCs) are, adult progenitors
Externí odkaz:
https://doaj.org/article/554fa31f6e9644108a9a6b4d65a35384
Autor:
Theodorus J.P. Jansen, Sevilay Tokgöz, Mijke Buitinga, Sanne A.M. van Lith, Lieke Joosten, Cathelijne Frielink, Esther M. M. Smeets, Martijn W.J. Stommel, Marion B. van der Kolk, Bastiaan E. de Galan, Maarten Brom, Marti Boss, Martin Gotthardt
Publikováno v:
EJNMMI Research, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Background Estimation of beta cell mass is currently restricted to evaluating pancreatic tissue samples, which provides limited information. A non-invasive imaging technique that reliably quantifies beta cell mass enables monitoring of chang
Externí odkaz:
https://doaj.org/article/32f406a66a7a4f579892ea9495c91ece
Publikováno v:
Nutrition Journal, Vol 23, Iss 1, Pp 1-9 (2024)
Abstract Background Type 2 diabetes mellitus (T2DM) is a chronic condition characterized by insulin resistance and impaired insulin production, leading to elevated blood glucose levels. Curcumin, a polyphenolic compound from Curcuma longa, has shown
Externí odkaz:
https://doaj.org/article/e383efc447424dd78485f514d987b12c
Publikováno v:
Zhongguo linchuang yanjiu, Vol 37, Iss 7, Pp 993-997 (2024)
Pancreatic regenerating (REG) protein belongs to the calcium-dependent lectin superfamily, and is encoded by regenerating gene. As secreted growth factors with multiple functions, REG protein family plays a regulatory role in nutrient metabolism, ant
Externí odkaz:
https://doaj.org/article/6a51b8bd00aa4d79b07e69471ffedc6b
Autor:
Stijn J. M. Niessen, Hans S. Kooistra, Yaiza Forcada, Charlotte R. Bjørnvad, Balazs Albrecht, Franziska Roessner, Esther Herberich, Carla Kroh
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 38, Iss 4, Pp 2099-2119 (2024)
Abstract Background Options for treatment of diabetes mellitus in cats are limited to insulin injections and monitoring for hypoglycemia. Hypothesis Once daily sodium‐glucose cotransporter‐2 inhibitor velagliflozin PO is noninferior to insulin in
Externí odkaz:
https://doaj.org/article/4d8ba0462e2b45a492cf80dac61f6185
Publikováno v:
Frontiers in Clinical Diabetes and Healthcare, Vol 5 (2024)
Externí odkaz:
https://doaj.org/article/1dbcdf152859454291c12844f6931d14
Autor:
Carmen L. Bayly, Xiao-Qing Dai, Cuilan Nian, Paul C. Orban, C. Bruce Verchere, Patrick E. MacDonald, Francis C. Lynn
Publikováno v:
Molecular Metabolism, Vol 89, Iss , Pp 102017- (2024)
Objective: Human embryonic stem cell (hESC; SC)-derived pancreatic β cells can be used to study diabetes pathologies and develop cell replacement therapies. Although current differentiation protocols yield SCβ cells with varying degrees of maturati
Externí odkaz:
https://doaj.org/article/fec9a33079604cce9f9fa718f5adb276