Zobrazeno 1 - 10
of 99
pro vyhledávání: '"bertrand huard"'
Autor:
Diane Giovannini, Aude Belbezier, Athan Baillet, Laurence Bouillet, Mitsuhiro Kawano, Chantal Dumestre-Perard, Giovanna Clavarino, Johan Noble, Jacques-Olivier Pers, Nathalie Sturm, Bertrand Huard
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The humoral response is frequently dysfunctioning in autoimmunity with a frequent rise in total serum immunoglobulins, among which are found autoantibodies that may be pathogenic by themselves and/or propagate the inflammatory reaction. The infiltrat
Externí odkaz:
https://doaj.org/article/a16f3fba5f024ce69ac6f18a6de6e189
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
A proliferation inducing ligand (APRIL) mediates a key role in the generation and survival of antibody-inducing plasmocytes. Based on this, APRIL has been targeted in autoimmune diseases including multiple sclerosis (MS) and optic neuritis (ON). In M
Externí odkaz:
https://doaj.org/article/f4e4d98106ee4325bdf1401a763ae5cd
Autor:
Nathalie Sturm, Melanie Quinterot, Jean-Philippe Guyot, Christian Righini, Willeke F. Daamen, Toin H. van Kuppevelt, Bertrand Huard
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
In mucosa such as tonsil, antibody-producing plasmocytes (PCs) lie in sub-epithelium space, which is thought to provide a suitable environment for their survival. A proliferation inducing ligand (APRIL) is one key survival factor for PCs present in t
Externí odkaz:
https://doaj.org/article/18f55dcee2034616acfdf0747dcc3279
Publikováno v:
Biomolecules, Vol 11, Iss 9, p 1349 (2021)
Glycosaminoglycans (GAGs) are linear anionic periodic polysaccharides participating in a number of biologically relevant processes in the extracellular matrix via interactions with their protein targets. Due to their periodicity, conformational flexi
Externí odkaz:
https://doaj.org/article/ad45b1c1699e48ae92d854c52950e455
Autor:
Cynthia M. Fehres, Nathalie O. van Uden, Nataliya G. Yeremenko, Leticia Fernandez, Gabriela Franco Salinas, Leonie M. van Duivenvoorde, Bertrand Huard, Jacques Morel, Hergen Spits, Michael Hahne, Dominique L. P. Baeten
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Regulatory B cells (Bregs) are immunosuppressive cells that modulate immune responses through multiple mechanisms. The signals required for the differentiation and activation of these cells remain still poorly understood. We have already shown that o
Externí odkaz:
https://doaj.org/article/c52da1b7f78341c89b1c697ffa766395
Autor:
Yang Gyun Kim, Montserrat Alvarez, Hitoshi Suzuki, Sachiko Hirose, Shozo Izui, Yasuhiko Tomino, Bertrand Huard, Yusuke Suzuki
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137044 (2015)
A proliferation-inducing ligand (APRIL) is a member of the tumor necrosis factor (TNF) superfamily. Despite advances in clinical and genetic studies, the details of the pathological roles of APRIL in IgA nephropathy (IgAN) remain to be fully defined.
Externí odkaz:
https://doaj.org/article/690ae2ac085b42c78a8002d131728da9
Autor:
Josquin Nys, Cristian R Smulski, Aubry Tardivel, Laure Willen, Christine Kowalczyk, Olivier Donzé, Bertrand Huard, Henry Hess, Pascal Schneider
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61350 (2013)
Myeloid cells express the TNF family ligands BAFF/BLyS and APRIL, which exert their effects on B cells at different stages of differentiation via the receptors BAFFR, TACI (Transmembrane Activator and CAML-Interactor) and/or BCMA (B Cell Maturation A
Externí odkaz:
https://doaj.org/article/2528627769644854b897c9c7dc2dcaf2
Autor:
Bertrand Huard, Ngoc Lan Tran, Mahdia Benkhoucha, Céline Manzin-Lorenzi, Marie-Laure Santiago-Raber
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31837 (2012)
SLE pathogenesis is complex, but it is now widely accepted that autoantibodies play a key role in the process by forming excessive immune complexes; their deposits within tissues leading to inflammation and functional damages. A proliferation inducin
Externí odkaz:
https://doaj.org/article/72d5bf875d9c4b9db2dcb7c2f6a878d4
Autor:
Peter O Hofgaard, Henriette C Jodal, Kurt Bommert, Bertrand Huard, Jo Caers, Harald Carlsen, Rolf Schwarzer, Nicole Schünemann, Franziska Jundt, Mona M Lindeberg, Bjarne Bogen
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51892 (2012)
Multiple myeloma (MM) is a lethal human cancer characterized by a clonal expansion of malignant plasma cells in bone marrow. Mouse models of human MM are technically challenging and do not always recapitulate human disease. Therefore, new mouse model
Externí odkaz:
https://doaj.org/article/4a38989cfeec4195b136cda0877e9b79
Autor:
Nathalie Sturm, Morgane Roger-Margueritat, Fabien Pierrel, Philippe Lehours, Muriel Genevay, Bertrand Huard
Publikováno v:
Journal of Leukocyte Biology. 113:376-382
Eosinophils may reside in the lower intestine to play several homeostatic functions. Regulation of IgA+ plasma-cell (PC) homeostasis is one of these functions. Here, we assessed regulation of expression for a proliferation-inducing ligand (APRIL), a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4b316f832af0c857c3903157cc116be
https://doi.org/10.1093/jleuko/qiad014
https://doi.org/10.1093/jleuko/qiad014