Zobrazeno 1 - 10
of 97
pro vyhledávání: '"berotralstat"'
Autor:
Richard E. Kast
Publikováno v:
Neuroglia, Vol 5, Iss 3, Pp 223-233 (2024)
Glioblastomas synthesize, bear receptors for, and respond to bradykinin, triggering migration and proliferation. Since centrifugal migration into uninvolved surrounding brain tissue occurs early in the course of glioblastoma, this attribute defeats l
Externí odkaz:
https://doaj.org/article/8536adef598e4941a4d8c2215dc6bfb0
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 19, Iss 1, Pp 1-10 (2024)
Abstract Background Hereditary angioedema (HAE) is a rare and potentially life-threatening disease that manifests clinically as recurrent episodes of swelling affecting multiple anatomical locations. Long-term prophylaxis (LTP) aims to control the di
Externí odkaz:
https://doaj.org/article/07047515d77d454f9ca53edccb0015a2
Autor:
Adil Adatia, Markus Magerl
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/645d1eea643b4b56a58da55c760f7639
Autor:
Anna Valerieva, Teresa Caballero, Markus Magerl, Joao P. Frade, Paul K. Audhya, Timothy Craig
Publikováno v:
Clinical and Translational Allergy, Vol 14, Iss 9, Pp n/a-n/a (2024)
Abstract Background Hereditary angioedema (HAE) is a rare genetic disorder characterized by unpredictable, debilitating episodes of submucosal and/or subcutaneous tissue swelling, which may be life‐threatening depending on anatomic location. The tw
Externí odkaz:
https://doaj.org/article/16eb12a496914dd2981f2fdef6712048
Autor:
Kanarek HJ, Mutschelknaus DAS
Publikováno v:
Journal of Asthma and Allergy, Vol Volume 17, Pp 123-132 (2024)
Henry J Kanarek,* Drew Austin Saville Mutschelknaus* Kanarek Allergy, Asthma & Immunology, Leawood, KS, USA*These authors contributed equally to this workCorrespondence: Henry J Kanarek, Tel +1 (913) 451-8555, Fax +1 (913) 327-8553, Email
Externí odkaz:
https://doaj.org/article/40a563a3e9da4d9aa339765b9d7b7aa3
Publikováno v:
Journal of Comparative Effectiveness Research, Vol 13, Iss 5 (2024)
Externí odkaz:
https://doaj.org/article/0f84a52f5f454695a2268ec5ca4094d6
Autor:
Daisuke Honda, MD, PhD, Michihiro Hide, MD, PhD, Tomoo Fukuda, MD, PhD, Keisuke Koga, MD, PhD, Eishin Morita, MD, PhD, Shinichi Moriwaki, MD, Yoshihiro Sasaki, MD, PhD, Yusuke Suzuki, MD, PhD, Phil Collis, PhD, Douglas T. Johnston, DO, Dianne Tomita, MPH, Bhavisha Desai, PharmD, Isao Ohsawa, MD, PhD
Publikováno v:
World Allergy Organization Journal, Vol 17, Iss 3, Pp 100882- (2024)
Background: Berotralstat is a once-daily oral inhibitor of plasma kallikrein for the prophylaxis of hereditary angioedema (HAE) in patients ≥12 years. APeX-J aimed to evaluate the efficacy and safety of berotralstat in Japan. Methods: APeX-J was a
Externí odkaz:
https://doaj.org/article/3b4e2445fcc64daeb7ca4e24132a6cc4
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundHereditary angioedema due to C1 inhibitor deficiency is a rare genetic condition that causes recurrent swelling with consequent functional impairment and decreased quality of life. Long-term prophylaxis (LTP) to prevent angioedema episodes
Externí odkaz:
https://doaj.org/article/6d5a4bb773cf4f118353ff6557552778
Autor:
Jonny G. Peter, MB ChB, MMed, FCP (SA), PhD, Bhavisha Desai, PharmD, Dianne Tomita, MPH, Phil Collis, PhD, Marcin Stobiecki, MD, PhD
Publikováno v:
World Allergy Organization Journal, Vol 16, Iss 11, Pp 100841- (2023)
Background: Given the recent approval of oral berotralstat in several countries for hereditary angioedema (HAE) prophylaxis, transition from long-term androgens to berotralstat may occur in clinical practice. The open-label, Phase II APeX-S trial pro
Externí odkaz:
https://doaj.org/article/7c11ba56ee47471087615c15e26f3f19
Publikováno v:
Therapeutics and Clinical Risk Management, Vol Volume 19, Pp 313-317 (2023)
Maximiliano Diaz-Menindez,1 Dan Morgenstern-Kaplan,2 Lyda Cuervo-Pardo,3 Santiago Alvarez-Arango,4,5 Alexei Gonzalez-Estrada6 1Division of Pulmonary, Allergy, and Sleep Medicine, Department of Medicine, Mayo Clinic, Jacksonville, FL, USA; 2Department
Externí odkaz:
https://doaj.org/article/77ea13b4db654f4699ced6ba3adde7bc