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pro vyhledávání: '"bee venom phospholipase a2"'
Akademický článek
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Autor:
Hyeon Joo Ham, Sang-Bae Han, Jaesuk Yun, In Jun Yeo, Young Wan Ham, Se Hyun Kim, Pil-Hoon Park, Dong-Young Choi, Jin Tae Hong
Publikováno v:
Translational Neurodegeneration, Vol 8, Iss 1, Pp 1-16 (2019)
Abstract Background Neuroinflammation and accumulation of β-amyloid (Aβ) play a significant role in the onset and progression of Alzheimer’s disease (AD). Our previous study demonstrated that signal transducer and activator of transcription-3 (ST
Externí odkaz:
https://doaj.org/article/96c687fe561f453ab483268626e09c6f
Autor:
Heejin Jo, Hyunjung Baek, Seon-Young Park, Bonhyuk Goo, Woo-Sang Jung, Hyunsu Bae, Sang-Soo Nam
Publikováno v:
Toxins, Vol 13, Iss 10, p 717 (2021)
Bee venom phospholipase A2 (bvPLA2) has been reported to have therapeutic effects such as neuroprotection, anti-inflammation, anti-nociception, anti-cancer properties, caused by increasing regulatory T cells (Tregs). The mechanism of Tregs modulation
Externí odkaz:
https://doaj.org/article/deeb7235289049b1a08c686815d543bb
Autor:
Hyeon Joo Ham, Ji Hye Han, Yong Sun Lee, Ki Cheon Kim, Jaesuk Yun, Shin Kook Kang, YangSu Park, Se Hyun Kim, Jin Tae Hong
Publikováno v:
Frontiers in Aging Neuroscience, Vol 11 (2019)
Neuroinflammation is important in the pathogenesis and development of Alzheimer’s disease (AD). In the AD brain, microglial activation and upregulation of pro-inflammatory mediators both induce amyloid beta (Aβ) accumulation. Regulatory T cells (T
Externí odkaz:
https://doaj.org/article/c9e20baea7bd42768488c339189e7183
Publikováno v:
Frontiers in Aging Neuroscience, Vol 11 (2019)
Parkinson’s disease (PD) is a chronic progressive neurodegenerative movement disorder characterized by the selective loss of dopaminergic neurons within the substantia nigra (SN). While the precise etiology of dopaminergic neuronal demise is elusiv
Externí odkaz:
https://doaj.org/article/1cf278d903444d8d9421b0c56983979e
Autor:
Hyunjung Baek, Seon-Young Park, Su Jeong Ku, Kihyun Ryu, Younsub Kim, Hyunsu Bae, Ye-Seul Lee
Publikováno v:
Toxins, Vol 12, Iss 3, p 198 (2020)
Bee venom phospholipase A2 is a lipolytic enzyme in bee venom that catalyzes hydrolysis of the sn-2 ester bond of membrane phospholipids to produce free fatty acid and lysophospholipids. Current evidence suggests that bee venom phospholipase A2 (bvPL
Externí odkaz:
https://doaj.org/article/7a1430134f7a4b81bf3c280074d2f03c
Publikováno v:
Frontiers in Aging Neuroscience, Vol 10 (2018)
Parkinson’s disease (PD) is the second most common neurodegenerative disorder worldwide. Progressive loss of dopaminergic neurons in the substantia nigra (SN) and their synaptic terminal connections in the striatum are main characterizations of PD.
Externí odkaz:
https://doaj.org/article/4eb680a6d0ec4e9ebe6aded0ca136f49
Autor:
Anamaria Zaharia, Ana-Mihaela Gavrila, Iuliana Caras, Bogdan Trica, Anita-Laura Chiriac, Catalina Ioana Gifu, Iulia Elena Neblea, Elena-Bianca Stoica, Sorin Viorel Dolana, Tanta-Verona Iordache
Publikováno v:
Polymers; Volume 14; Issue 19; Pages: 4200
In this study, ligand-free nanogels (LFNGs) as potential antivenom mimics were developed with the aim of preventing hypersensitivity and other side effects following massive bee attacks. For this purpose, poly (ethylene glycol) diacrylate was chosen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7543b4b79dd8e1d63272684c16fcd78
Autor:
Hyunjung Baek, HyeJin Yang, Jong Hoon Lee, Na-Hoon Kang, Jinwook Lee, Hyunsu Bae, Deok-Sang Hwang
Publikováno v:
Toxins, Vol 11, Iss 7, p 404 (2019)
Spontaneous abortion represents a common form of embryonic loss caused by early pregnancy failure. In the present study, we investigated the prophylactic effects of bee venom phospholipase A2 (bvPLA2), a regulatory T cell (Treg) inducer, on a lipopol
Externí odkaz:
https://doaj.org/article/a185414529fa40f282249d294dd2578c
Publikováno v:
Toxins, Vol 10, Iss 4, p 146 (2018)
Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by highly pruritic, erythematous, and eczematous skin plaques. We previously reported that phospholipase A2 (PLA2) derived from bee venom alleviates AD-like skin lesions indu
Externí odkaz:
https://doaj.org/article/5ffec42210d6489a844bffcb910d91e3