Zobrazeno 1 - 10
of 6 246
pro vyhledávání: '"bcl2"'
Autor:
Elham Hemati, Hossein Sazegar
Publikováno v:
Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, Vol 32, Iss 7, Pp 8056-8066 (2024)
Introduction: Accumulating evidence has revealed that inducing apoptosis is an important strategy to control excessive breast cancer cell proliferation. In this study, the supernatant effect of the probiotic strain of Lactobacillus Sakei on Expressio
Externí odkaz:
https://doaj.org/article/93e94c59d74840bebe8e497c13658bd5
Autor:
Fatma Alzahraa Abdelsalam ELKHAMISY, Ahmed Naeem EESA, Marwa Kamal SALLAM, Marwa Fathy HUSSEIN, Nadia Ahmed ABD EL-MOEZE
Publikováno v:
Türk Patoloji Dergisi, Vol 40, Iss 3, Pp 162-169 (2024)
Objective: Some histological basal cell carcinoma (BCC) types demonstrate more aggressive behavior than others. They are known as high-risk BCC and are more challenging in therapy, contrary to indolent (low-risk) BCC types. Identifying novel protein
Externí odkaz:
https://doaj.org/article/c4cb44195d0c45aa84c45fe62414c452
Autor:
Qingjie Li, Qiaofeng Zhou, Shihuan Li, Suqin Li, Wenli Liao, Liangzhu Yu, Chao Liu, Mincai Li, Hongli Xia
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract To investigate the mechanism of curcumin (CUR) on vascular calcification (VC), we screen for common targets of CUR and atherosclerosis and verify the targets genes in vivo and in vitro experiments. The common targets of CUR and AS were scree
Externí odkaz:
https://doaj.org/article/656e6d0755c346ec8c80b0c91795d472
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Cancer and related disorders are the most common cause of cancer-related mortality with the incidence of 1 in 9 among the pre-menopausal Pakistani females. among the most common ailments worldwide, indicating the importance of developing par
Externí odkaz:
https://doaj.org/article/1474aaf928274dd9ae7346cc4f1eee64
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-16 (2024)
Abstract High-grade B-cell lymphoma (HGBCL), the subtype of non-Hodgkin lymphoma, to be relapsed or refractory in patients after initial therapy or salvage chemotherapy. Dual dysregulation of MYC and BCL2 is one of the important pathogenic mechanisms
Externí odkaz:
https://doaj.org/article/b2e63d2e364d46c0b5e25a19a5ad1487
Publikováno v:
Case Reports in Oncology, Vol 17, Iss 1, Pp 614-621 (2024)
Introduction: Primary breast lymphoma represents only 1% of non-Hodgkin lymphomas. The most common histology is diffuse large B-cell lymphoma. When dual translocations of MYC and BCL2 or BCL6 occur, it is referred to as “high-grade B-cell lymphoma
Externí odkaz:
https://doaj.org/article/0cfad89bd6744b889c20e695af7994ed
Autor:
Quancheng Han, Yan Li, Yiding Yu, Huajing Yuan, Ziqi Wang, Yonghong Guo, Jingle Shi, Yitao Xue, Xiujuan Liu
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Despite its effectiveness in treating diabetic cardiomyopathy (DCM), Qigui Qiangxin Mixture (QGQXM) remains unclear in terms of its active ingredients and specific mechanism of action. The purpose of this study was to explore the active ingr
Externí odkaz:
https://doaj.org/article/891c187741a94ad7bfeb71fa4bdd7741
Autor:
Shiqiang Xu, Qilian Ma, Junwen Shen, Ningning Li, Shan Sun, Nana Wang, Yang Chen, Chunsheng Dong, Kin Yip Tam, Jochen H.M. Prehn, Hongfeng Wang, Zheng Ying
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 5, Pp 2026-2038 (2024)
Growing evidences indicate that dysfunction of autophagy contributes to the disease pathogenesis of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), two neurodegenerative disorders. The GGGGCC·GGCCCC repeat RNA expansion in chr
Externí odkaz:
https://doaj.org/article/dbd1fbe959004134a85764e04d7c0c51
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 4, Pp 2946-2960 (2024)
Targeting the FLT3 receptor and the IL-1R associated kinase 4 as well as the anti-apoptotic proteins MCL1 and BCL2 may be a promising novel approach in the treatment of acute myeloid leukemia (AML). The FLT3 and IRAK4 inhibitor emavusertib (CA4948),
Externí odkaz:
https://doaj.org/article/ab41290b58f549f1851ded0efc64d10f
Publikováno v:
مجلة جامعة دمشق للعلوم الطبية, Vol 40, Iss 3 (2024)
Background and Aim: c-MYC is a potent transcription factor involved in several cellular processes, and is overexpressed in many cancers, including non-Hodgkin lymphoma (NHL). The most common subtype of NHL is diffuse large B-cell lymphoma (DLBCL). DL
Externí odkaz:
https://doaj.org/article/f0a3d021ce3e46b7b5e8a3a34082b511