Zobrazeno 1 - 10
of 118
pro vyhledávání: '"bacterium-like particles"'
Autor:
Xinqi De, Mingchun Gao, Zheng Jia, Hongkun Ren, Runhang Liu, Xinyao Zhou, Junjie Guo, Jiaqing Wang, Qi Yu, Nanzhu Qu, Fang Wang, Junwei Ge
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Bacterium-like particles (BLPs) have gained significant attention in vaccine development due to their potential as effective immune enhancers and antigen delivery systems. BLPs are generated by boiling lactic acid bacteria in an acidic solution and a
Externí odkaz:
https://doaj.org/article/c373232576cb4a179980f6a94a078835
Autor:
Lingdi Niu, Mingchun Gao, Hongkun Ren, Xinqi De, Zhigang Jiang, Xinyao Zhou, Runhang Liu, Hai Li, Haoyuan Duan, Chuankun Zhang, Fang Wang, Junwei Ge
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Bacterium-like particles (BLP) are the peptidoglycan skeleton particles of lactic acid bacteria, which have high safety, mucosal delivery efficiency, and adjuvant effect. It has been widely used in recent years in the development of vaccines. Existin
Externí odkaz:
https://doaj.org/article/78adb3daccf748c9a77d69384eff618f
Autor:
Jianzhong Wang, Lina Liu, Xianchun Zong, Chunliu Wang, Guangmei Zhu, Guilian Yang, Yanlong Jiang, Wentao Yang, Haibin Huang, Chunwei Shi, Yan Zeng, Nan Wang, Xin Cao, Chunfeng Wang, Na Feng
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 4 (2024)
ABSTRACTCanine distemper virus (CDV) poses a severe threat to both domesticated and wild animals, including multiple carnivores. With the continued expansion of its host range, there is an urgent need for the development of a safer and more effective
Externí odkaz:
https://doaj.org/article/d73ce3a0f0a34d7788d8b2e11f71bd51
Autor:
Ruifeng Mao, Jin Wang, Ying Xu, Yuqi Wang, Mengmeng Wu, Lixia Mao, Yingying Chen, Dengchao Li, Tong Zhang, Enjie Diao, Zhenjing Chi, Yefu Wang, Xin Chang
Publikováno v:
Drug Delivery, Vol 30, Iss 1 (2023)
AbstractInduction of oral tolerance by vaccination with type 1 diabetes mellitus (T1DM)-associated autoantigens exhibits great potential in preventing and treating this autoimmune disease. However, antigen degradation in the gastrointestinal tract (G
Externí odkaz:
https://doaj.org/article/9809eb1192604a52b60c2633ce824dce
Autor:
Ramiro Ortiz Moyano, Fernanda Raya Tonetti, Mariano Elean, Yoshiya Imamura, Kohtaro Fukuyama, Yoshihito Suda, Vyacheslav Melnikov, Alexander Suvorov, María Guadalupe Vizoso-Pinto, Haruki Kitazawa, Julio Villena
Publikováno v:
Vaccines, Vol 12, Iss 4, p 412 (2024)
Previously, it was shown that intranasally (i.n.) administered Corynebacterium pseudodiphtheriticum 090104 (Cp) or CP-derived bacterium-like particles (BLPs) improve the immunogenicity of the pneumococcal conjugate vaccine (PCV). This work aimed to d
Externí odkaz:
https://doaj.org/article/1fa906a2be164011972f5c33c4928d75
Autor:
Lina Liu, Jianzhong Wang, Ranran Li, Jianzhao Wu, Yongkun Zhao, Feihu Yan, Tiecheng Wang, Yuwei Gao, Zongzheng Zhao, Na Feng, Xianzhu Xia
Publikováno v:
Viruses, Vol 16, Iss 4, p 549 (2024)
Canine distemper virus (CDV) can cause fatal infections in giant pandas. Vaccination is crucial to prevent CDV infection in giant pandas. In this study, two bacterium-like particle vaccines F3-GEM and H4-GEM displaying the trimeric F protein or tetra
Externí odkaz:
https://doaj.org/article/5b8437c2492a42a29b7d212ffd4c6710
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Bacterium-like particles (BLPs) are hollow peptidoglycan particles obtained from food-grade Lactococcus lactis inactivated by hot acid. With the advantage of easy preparation, high safety, great stability, high loading capacity, and high mucosal deli
Externí odkaz:
https://doaj.org/article/9d0043ba16f94c9e9cf7975cf2160267
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Porcine epidemic diarrhea virus (PEDV) causes acute watery diarrhea and high mortality in newborn piglets. Activation of intestinal mucosal immunity is crucial to anti-PEDV infection. To develop a vaccine capable of stimulating intestinal mucosal imm
Externí odkaz:
https://doaj.org/article/6d5a34721ec44008b916fd61b6050df6
Autor:
Ruifeng Mao, Menglan Yang, Rui Yang, Yingying Chen, Enjie Diao, Tong Zhang, Dengchao Li, Xin Chang, Zhenjing Chi, Yefu Wang
Publikováno v:
Drug Delivery, Vol 29, Iss 1, Pp 925-936 (2022)
Antigen-specific immune tolerance, which possesses great potential in preventing or curing type 1 diabetes mellitus (T1DM), can be induced by oral vaccination with T1DM-related autoantigens. However, direct administration of autoantigens via oral rou
Externí odkaz:
https://doaj.org/article/692454666a994d669fa053ccf05b97a3
Autor:
Haruka Sudo, Nagisa Tokunoh, Ayato Tsujii, Sarana Kawashima, Yuta Hayakawa, Hiroki Fukushima, Keita Takahashi, Tetsuo Koshizuka, Naoki Inoue
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Direct administration of vaccines to mucosal surfaces, such as via oral or nasal vaccination, represents an attractive alternative, or complement, to current parenteral vaccination because it has a potential to induce antigen-specific immunity both a
Externí odkaz:
https://doaj.org/article/26d1b7d15ef0407ba0544d17091ac30f