Lipid A in outer membrane vesicles shields bacteria from polymyxins

Autor: Marie Burt, Georgia Angelidou, Christopher Nils Mais, Christian Preußer, Timo Glatter, Thomas Heimerl, Rüdiger Groß, Javier Serrania, Gowtham Boosarpu, Elke Pogge von Strandmann, Janis A. Müller, Gert Bange, Anke Becker, Mareike Lehmann, Danny Jonigk, Lavinia Neubert, Hinrich Freitag, Nicole Paczia, Bernd Schmeck, Anna Lena Jung

Publikováno v: Journal of Extracellular Vesicles, Vol 13, Iss 5, Pp n/a-n/a (2024)

Abstract The continuous emergence of multidrug‐resistant bacterial pathogens poses a major global healthcare challenge, with Klebsiella pneumoniae being a prominent threat. We conducted a comprehensive study on K. pneumoniae’s antibiotic resistan

Externí odkaz: https://doaj.org/article/d578823b51904a85bb20616a75988ddc

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Editorial : bad bugs in the XXIst century: resistance mediated by multi-drug efflux pumps in gram-negative bacteria

Autor: Klaas M. Pos, Keith Poole, Attilio Vittorio Vargiu, Hiroshi Nikaido

Publikováno v: Bad Bugs in the XXIst Century: Resistance Mediated by Multi-Drug Efflux Pumps in Gram-Negative Bacteria
Frontiers in Microbiology, Vol 7 (2016)
Frontiers in Microbiology

The discovery of antibiotics represented a key milestone in the history of medicine. However, with the rise of these life-saving drugs came the awareness that bacteria deploy defense mechanisms to resist these antibiotics, and they are good at it. To

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22401922f89a09e8d4e17487e6301e7f
http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/50597

Extreme antimicrobial peptide and polymyxin B resistance in the genus Burkholderia

Autor: Miguel A. Valvano, Slade A. Loutet

Publikováno v: Frontiers in Cellular and Infection Microbiology
Frontiers in Cellular and Infection Microbiology, Vol 1 (2011)
Frontiers in Microbiology

Cationic antimicrobial peptides and polymyxins are a group of naturally occurring antibiotics that can also possess immunomodulatory activities. They are considered a new source of antibiotics for treating infections by bacteria that are resistant to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44f0e99549d911e3851b502955d25f32
https://doi.org/10.3389/fcimb.2011.00006

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