Zobrazeno 1 - 10
of 489
pro vyhledávání: '"b cell lymphoma-2"'
Publikováno v:
Shipin Kexue, Vol 45, Iss 15, Pp 205-213 (2024)
In order to investigate the regulatory effect of B-cell lymphoma-2 (Bcl-2) on cell apoptosis and water retention in postmortem Qinchuan beef, the longissimus dorsi muscle of Qinchuan cattle was injected with either 200 μmol/L glycochenodeoxycholic a
Externí odkaz:
https://doaj.org/article/d13e054515704cbabd43824ff4965bc8
Publikováno v:
Hematology, Vol 29, Iss 1 (2024)
Objectives Acute undifferentiated leukemia (AUL) is a clinical rare leukemia with an overall poor prognosis. Currently, there are no well-established treatment guidelines for AUL, further exploration of optimal treatment options is now required.Metho
Externí odkaz:
https://doaj.org/article/4be534718bff4476bd8266fa267155a6
Akademický článek
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Publikováno v:
Renal Failure, Vol 44, Iss 1, Pp 1961-1975 (2022)
Background Given the reported effects of nuclear paraspeckle assembly transcript 1 (NEAT1) on kidney injury, a study is worth formulating to investigate whether and how NEAT1 impacts podocytes.Materials and methods A mouse podocyte injury model was e
Externí odkaz:
https://doaj.org/article/aca23ef2c4ec4a1d8dd8870f8d873670
Autor:
Hiroyuki Murakami, Ken-ichi Matsuoka, Takeru Asano, Takashi Moriyama, Akifumi Matsumura, Hideaki Fujiwara, Noboru Asada, Daisuke Ennishi, Hisakazu Nishimori, Keiko Fujii, Nobuharu Fujii, Tomohiro Toji, Tadashi Yoshino, Yoshinobu Maeda
Publikováno v:
Case Reports in Oncology, Vol 15, Iss 3, Pp 974-979 (2022)
Venetoclax (VEN) is an oral B-cell lymphoma-2 (BCL-2) inhibitor that has been widely used to treat various hematological disorders. Recent studies have demonstrated that VEN in combination with fludarabine-enhanced high-dose cytarabine (FLA) is effec
Externí odkaz:
https://doaj.org/article/6449389864ef4dcf9ad610c2ccc123d8
Autor:
Chansub Lee, Sungyoung Lee, Eunchae Park, Junshik Hong, Dong-Yeop Shin, Ja Min Byun, Hongseok Yun, Youngil Koh, Sung-Soo Yoon
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-13 (2022)
Abstract Background Although anti-apoptotic proteins of the B-cell lymphoma-2 (BCL2) family have been utilized as therapeutic targets in acute myeloid leukaemia (AML), their complicated regulatory networks make individualized therapy difficult. This
Externí odkaz:
https://doaj.org/article/2edfb708cf564e0197a24b7f6d872da2
Autor:
Prasad Sulkshane, Tanuja Teni
Publikováno v:
Exploration of Targeted Anti-tumor Therapy, Vol 3, Iss 3, Pp 278-296 (2022)
The antiapoptotic B cell lymphoma-2 (Bcl-2) family members are apical regulators of the intrinsic pathway of apoptosis that orchestrate mitochondrial outer membrane permeabilization (MOMP) through interactions with their proapoptotic counterparts. Ov
Externí odkaz:
https://doaj.org/article/93986c4e1e2c4b9ebc28fc2e922f3483
Akademický článek
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Autor:
Hittanahallikoppal Gajendramurthy Gowtham, Faiyaz Ahmed, Satish Anandan, C. S. Shivakumara, Ashween Bilagi, Sushma Pradeep, Chandan Shivamallu, Ali A. Shati, Mohammad Y. Alfaifi, Serag Eldin I. Elbehairi, Raghu Ram Achar, Ekaterina Silina, Victor Stupin, Mahadevamurthy Murali, Shiva Prasad Kollur
Publikováno v:
Molecules, Vol 28, Iss 4, p 1588 (2023)
In the present study, the binding affinity of 52 bioactive secondary metabolites from Wedelia trilobata towards the anti-apoptotic B-cell lymphoma-2 (Bcl-2) protein (PDB: 2W3L) structure was identified by using in silico molecular docking and molecul
Externí odkaz:
https://doaj.org/article/b2be074a1fce4eb3b3b69b7d346417b8
Akademický článek
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