Zobrazeno 1 - 10
of 1 688
pro vyhledávání: '"b cell epitope"'
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 2695-2707 (2024)
Background: The accurate computational prediction of B cell epitopes can vastly reduce the cost and time required for identifying potential epitope candidates for the design of vaccines and immunodiagnostics. However, current computational tools for
Externí odkaz:
https://doaj.org/article/2693960953f94fd18bcf44205e276a37
Autor:
Xiaodong Wang, Xiangrui Gao, Xuezhe Fan, Zhe Huai, Genwei Zhang, Mengcheng Yao, Tianyuan Wang, Xiaolu Huang, Lipeng Lai
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 2122-2131 (2024)
B-cell epitope identification plays a vital role in the development of vaccines, therapies, and diagnostic tools. Currently, molecular docking tools in B-cell epitope prediction are heavily influenced by empirical parameters and require significant c
Externí odkaz:
https://doaj.org/article/35e0600152f54379b34253ae74639f5a
Autor:
Jing LIU, Xiuzhang XU, Haoqiang DING, Jing DENG, Jiali WANG, Yangkai CHEN, Wenjie XIA, Xin YE
Publikováno v:
Zhongguo shuxue zazhi, Vol 37, Iss 8, Pp 853-858 (2024)
Objective To analyze the structure of CD36, search the possible B cell epitopes and prepare multi-antigen peptides(MAP) with B cell epitopes, so as to provide a preliminary experimental basis for the preparation of CD36 antibodies using MAP with B ce
Externí odkaz:
https://doaj.org/article/ec40454ee2004a549271f053009283e5
Autor:
Ahyar Ahmad, Abdul Karim, Rugaiyah A. Arfah, Rosana Agus, Rusdina Bte Ladju, Najdah Hidayah, Muhammad N. Massi, Astutiati Nurhasanah, Harningsih Karim, Irda Handayani, Rizal Irfandi
Publikováno v:
Emerging Science Journal, Vol 8, Iss 4, Pp 1345-1365 (2024)
The efficacy of the BCG vaccine, a widely recognized tuberculosis vaccine, has shown varying degrees of effectiveness, ranging from 0% to 80%. Sirohydrochlorin cobaltochelatase (CbiX), found in Mycobacterium tuberculosis, plays a crucial role in the
Externí odkaz:
https://doaj.org/article/49af83ed1d1e47efb6086b90dbe1589b
Autor:
Zui Wang, Lina Liu, Junfeng Dou, Li Li, Qin Lu, Xinxin Jin, Huabin Shao, Zhengyu Cheng, Tengfei Zhang, Qingping Luo, Weicheng Bei
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 6, Pp 5866-5880 (2024)
Avian leukosis virus (ALV) is an avian oncogenic retrovirus that can impair immunological function, stunt growth and decrease egg production in avian flocks. The capsid protein (P27) is an attractive candidate for ALV diagnostics. In the present stud
Externí odkaz:
https://doaj.org/article/c6fbac9ad23e44c2b18d009cee421b70
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Canine kobuvirus (CaKoV) is a pathogen associated with canine gastrointestinal disease (GID). This study examined 327 rectal swabs (RS), including 113 from Vietnam (46 healthy, 67 with GID) and 214 from Thailand (107 healthy and 107 with GID
Externí odkaz:
https://doaj.org/article/799564a4804143069df3d0c3f6bff76f
Publikováno v:
Guangdong nongye kexue, Vol 51, Iss 3, Pp 124-135 (2024)
【Objective】The study was carried out to understand the genetic evolution of Porcine Circovirus Type 2 (PCV2) strains on a swine farm in Guangdong Province, and enrich molecular epidemiological data of PCV2, in order to provide reference for the s
Externí odkaz:
https://doaj.org/article/f9641e359f5a4c58a90fe45c90507a90
Autor:
Shuqin Gu, Libo Tang, Ling Guo, Chunxiu Zhong, Xin Fu, Guofu Ye, Shihong Zhong, Xiaoyi Li, Chunhua Wen, Yang Zhou, Jinling Wei, Haitao Chen, Nikolai Novikov, Simon P. Fletcher, M. Anthony Moody, Jinlin Hou, Yongyin Li
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
It is well established that humoral immunity targeting hepatitis B virus surface antigen (HBsAg) plays a critical role in viral clearance and clinical cure. However, the functional changes in HBsAg-specific B cells before and after achieving function
Externí odkaz:
https://doaj.org/article/f7d734b3c4d9471c9d5b1528dfa1a03e
Publikováno v:
mAbs, Vol 16, Iss 1 (2024)
ABSTRACTThe surge in the clinical use of therapeutic antibodies has reshaped the landscape of pharmaceutical therapy for many diseases, including rare and challenging conditions. However, the administration of exogenous biologics could potentially tr
Externí odkaz:
https://doaj.org/article/35791c01bb7b437085106c688356d180
Autor:
Weldu Tesfagaber, Desong Lan, Wan Wang, Rui Zhao, Li Yin, Mingyang Yang, Yuanmao Zhu, Encheng Sun, Renqiang Liu, Wenjun Lin, Zhigao Bu, Fang Li, Dongming Zhao
Publikováno v:
Virus Research, Vol 346, Iss , Pp 199412- (2024)
African swine fever virus (ASFV) is a large double-stranded DNA virus with a complex structural architecture and encodes more than 150 proteins, where many are with unknown functions. E184L has been reported as one of the immunogenic ASFV proteins th
Externí odkaz:
https://doaj.org/article/beb51e1c8a33490aa62c64639a1795f7