Mycobacterial biotin synthases require an auxiliary protein to convert dethiobiotin into biotin

Autor: Di Qu, Peng Ge, Laure Botella, Sae Woong Park, Ha-Na Lee, Natalie Thornton, James M. Bean, Inna V. Krieger, James C. Sacchettini, Sabine Ehrt, Courtney C. Aldrich, Dirk Schnappinger

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)

Abstract Lipid biosynthesis in the pathogen Mycobacterium tuberculosis depends on biotin for posttranslational modification of key enzymes. However, the mycobacterial biotin synthetic pathway is not fully understood. Here, we show that rv1590, a gene

Externí odkaz: https://doaj.org/article/3054e679f3564df091570ea68d735626

Auxiliary protein and chaperone regulation of neuronal nicotinic receptor subtype expression and function

Autor: Gotti, Cecilia, Clementi, Francesco, Zoli, Michele

Publikováno v: In Pharmacological Research February 2024 200

Phosphorylation of P-stalk proteins defines the ribosomal state for interaction with auxiliary protein factors.

Autor: Filipek K; Department of Molecular Biology, Institute of Biological Sciences, Maria Curie-Skłodowska University, Lublin, Poland., Blanchet S; Department of Physical Biochemistry, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany.; Institute for Integrative Biology of the Cell, I2BC, CEA, CNRS, Université Paris-Saclay, Gif-sur-Yvette, France., Molestak E; Department of Molecular Biology, Institute of Biological Sciences, Maria Curie-Skłodowska University, Lublin, Poland., Zaciura M; Department of Molecular Biology, Institute of Biological Sciences, Maria Curie-Skłodowska University, Lublin, Poland., Wu CC; Department of Molecular Biology and Genetics, Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Section of Translational Control of Gene Expression, RNA Biology Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA., Horbowicz-Drożdżal P; Department of Molecular Biology, Institute of Biological Sciences, Maria Curie-Skłodowska University, Lublin, Poland., Grela P; Department of Molecular Biology, Institute of Biological Sciences, Maria Curie-Skłodowska University, Lublin, Poland., Zalewski M; Biological and Chemical Research Center, Faculty of Chemistry, University of Warsaw, Warsaw, Poland., Kmiecik S; Biological and Chemical Research Center, Faculty of Chemistry, University of Warsaw, Warsaw, Poland., González-Ibarra A; Department of Molecular Biology, Institute of Biological Sciences, Maria Curie-Skłodowska University, Lublin, Poland., Krokowski D; Department of Molecular Biology, Institute of Biological Sciences, Maria Curie-Skłodowska University, Lublin, Poland., Latoch P; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland., Starosta AL; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland., Mołoń M; Institute of Biology, University of Rzeszow, Rzeszow, Poland., Shao Y; Department of Molecular Biology, Institute of Biological Sciences, Maria Curie-Skłodowska University, Lublin, Poland., Borkiewicz L; Department of Molecular Biology, Institute of Biological Sciences, Maria Curie-Skłodowska University, Lublin, Poland.; Department of Biochemistry and Molecular Biology, Medical University of Lublin, Aleje Racławickie 1, 20-059, Lublin, Poland., Michalec-Wawiórka B; Department of Molecular Biology, Institute of Biological Sciences, Maria Curie-Skłodowska University, Lublin, Poland., Wawiórka L; Department of Molecular Biology, Institute of Biological Sciences, Maria Curie-Skłodowska University, Lublin, Poland., Kubiński K; Department of Molecular Biology, Institute of Biological Sciences, John Paul II Catholic University of Lublin, Lublin, Poland., Socała K; Department of Animal Physiology and Pharmacology, Institute of Biological Sciences, Maria Curie-Skłodowska University, Lublin, Poland., Wlaź P; Department of Animal Physiology and Pharmacology, Institute of Biological Sciences, Maria Curie-Skłodowska University, Lublin, Poland., Cunningham KW; Department of Biology, Johns Hopkins University, Baltimore, MD, USA. kwc@jhu.edu., Green R; Department of Molecular Biology and Genetics, Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA. ragreen@jhmi.edu., Rodnina MV; Department of Physical Biochemistry, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany. rodnina@mpinat.mpg.de., Tchórzewski M; Department of Molecular Biology, Institute of Biological Sciences, Maria Curie-Skłodowska University, Lublin, Poland. marek.tchorzewski@mail.umcs.pl.

Publikováno v: EMBO reports [EMBO Rep] 2024 Oct 28. Date of Electronic Publication: 2024 Oct 28.

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Potential roles of Cornichon Family AMPA Receptor Auxiliary Protein 4 (CNIH4) in head and neck squamous cell carcinoma.

Autor: Liu, Hengrui¹ (AUTHOR) lh@yinuobiomedical.cn, Li, Yixue^2,3 (AUTHOR)

Publikováno v: Cancer Biomarkers. 2022, Vol. 35 Issue 4, p439-450. 12p.