Zobrazeno 1 - 10
of 315
pro vyhledávání: '"autophagosome–lysosome fusion"'
Publikováno v:
Autophagy Reports, Vol 3, Iss 1 (2024)
Macroautophagy (also known as autophagy) plays a pivotal role in maintaining cellular homeostasis. The terminal step of the multi-step autophagy degradation pathway involves fusion between the cargo-laden, double-membraned autophagosome and the lytic
Externí odkaz:
https://doaj.org/article/bab6517028f847d4af9dab11262e1bd0
Publikováno v:
Journal of Extracellular Vesicles, Vol 13, Iss 11, Pp n/a-n/a (2024)
Abstract The identification of both autophagy‐related material degradation and unconventional secretion has paved the way for significant breakthroughs linking autophagy to a plethora of physiological processes and disease conditions. However, the
Externí odkaz:
https://doaj.org/article/7a0056aff96d480e83b4c69ceac564be
Autor:
Yizhi Zhang, Wan Li, Yihui Yang, Sen Zhang, Hong Yang, Yue Hao, Xu Fang, Guanhua Du, Jianyou Shi, Lianqiu Wu, Jinhua Wang
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-18 (2024)
Abstract Background Glioblastoma (GBM) is the most common brain tumor with the worst prognosis. Temozolomide is the only first-line drug for GBM. Unfortunately, the resistance issue is a classic problem. Therefore, it is essential to develop new drug
Externí odkaz:
https://doaj.org/article/01fbfd9d0f554ad6bc9eb31003ab2d4a
Publikováno v:
Cell Insight, Vol 3, Iss 2, Pp 100152- (2024)
Autophagy, a lysosome-dependent degradation process, plays a crucial role in maintaining cell homeostasis. It serves as a vital mechanism for adapting to stress and ensuring intracellular quality control. Autophagy deficiencies or defects are linked
Externí odkaz:
https://doaj.org/article/4c1561a801314c5aa81b5304ef9f1ea0
Autor:
Po-Yuan Ke
Publikováno v:
Cells, Vol 13, Iss 6, p 500 (2024)
In eukaryotes, targeting intracellular components for lysosomal degradation by autophagy represents a catabolic process that evolutionarily regulates cellular homeostasis. The successful completion of autophagy initiates the engulfment of cytoplasmic
Externí odkaz:
https://doaj.org/article/a394f9ca6c204c218136d7d6e704fab8
Autor:
Po-Yuan Ke
Publikováno v:
Pathogens, Vol 13, Iss 3, p 266 (2024)
Autophagy plays a fundamental role in maintaining cellular homeostasis by eliminating intracellular components via lysosomes. Successful degradation through autophagy relies on the fusion of autophagosomes to lysosomes, which leads to the formation o
Externí odkaz:
https://doaj.org/article/c2357872e42e487ab6da85a4da9e8916
Akademický článek
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Akademický článek
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Autor:
Chi, Congwu, Leonard, Andrea, Knight, Walter E., Beussman, Kevin M., Zhao, Yuanbiao, Cao, Yingqiong, Londono, Pilar, Aune, Ellis, Trembley, Michael A., Small, Eric M., Jeong, Mark Y., Walker, Lori A., Xu, Hongyan, Sniadecki, Nathan J., Taylor, Matthew R., Buttrick, Peter M., Song, Kunhua
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2019 Jan 01. 116(2), 556-565.
Externí odkaz:
https://www.jstor.org/stable/26574066
Autor:
Yuanli Zhang, Xie Han, Yanling Tang, Jingjing Zhang, Zeyu Hu, Wanjing Xu, Ping Yao, Qiang Niu
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 230, Iss , Pp 113108- (2022)
Fluoride is capable of inducing developmental neurotoxicity, but the mechanisms involved remain unclear. We aimed to explore the role of autophagosome-lysosome fusion in developmental fluoride neurotoxicity, particularly focusing on the interaction b
Externí odkaz:
https://doaj.org/article/240178e6d40d4a42926b0fe1f56930ea