Zobrazeno 1 - 10
of 785
pro vyhledávání: '"autolysosome"'
Autor:
Qiaohui Shen, Ming Yang, Song Wang, Xingyu Chen, Sulan Chen, Rui Zhang, Zhuang Xiong, Yan Leng
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Non-alcoholic fatty liver disease (NAFLD) is a clinicopathologic syndrome characterized by excessive fat deposition in hepatocytes and a major cause of end-stage liver disease. Autophagy is a metabolic pathway responsible for degrading cytoplasmic pr
Externí odkaz:
https://doaj.org/article/53d6342e67de4bf48fbe8aba0729cbf2
Autor:
Chang Xiao, Yue Sun, Jialong Fan, William Nguyen, Simin Chen, Ying Long, Wei Chen, Aiguo Zhu, Bin Liu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 11, Pp 4591-4606 (2023)
Although carbon monoxide (CO)-based treatments have demonstrated the high cancer efficacy by promoting mitochondrial damage and core-region penetrating ability, the efficiency was often compromised by protective autophagy (mitophagy). Herein, cannabi
Externí odkaz:
https://doaj.org/article/b6ff2a2557d043e79b1a77eca8433bc3
Autor:
Maria V. M. Scervino, Marco A. S. Fortes, Kaio F. Vitzel, Diego R. deSouza, Gilson M. Murata, Giovanna O. Santana, Eliane B. daSilva, Adriana C. Levada‐Pires, Wilson M. T. Kuwabara, Tatiana C. A. Loureiro, Rui Curi
Publikováno v:
FEBS Open Bio, Vol 13, Iss 9, Pp 1709-1722 (2023)
Autophagy plays a vital role in cell homeostasis by eliminating nonfunctional components and promoting cell survival. Here, we examined the levels of autophagy signaling proteins after 7 days of overload hypertrophy in the extensor digitorum longus (
Externí odkaz:
https://doaj.org/article/952bb9807c304abfa7ef68e5adfc3bc0
Autor:
Julie Vérièpe-Salerno, Silvia Podavini, Marcus J.C. Long, Irina Kolotuev, Muriel Cuendet, Margot Thome
Publikováno v:
Autophagy Reports, Vol 2, Iss 1 (2023)
ABSTRACTThe caspase-like protease MALT1 promotes immune responses and oncogenesis in mammals by activating the transcription factor NF-κB. MALT1 is remarkably conserved from mammals to simple metazoans devoid of NF-κB homologs, like the nematode C.
Externí odkaz:
https://doaj.org/article/9017f52a22e24476855b5e43851ab9a5
Autor:
Abdul Alim Al-Bari
Publikováno v:
All Life, Vol 15, Iss 1, Pp 568-601 (2022)
Autophagy process coordinates lysosomal destruction of cytoplasmic materials including damaged organelles and proteins. The double-membranous ‘autophagosome’ selectively sequesters the cytosolic components, followed by ‘autolysosome’ formatio
Externí odkaz:
https://doaj.org/article/0601bf7aa58144d389d28681125f01c0
Autor:
Po-Yuan Ke
Publikováno v:
Cells, Vol 13, Iss 6, p 500 (2024)
In eukaryotes, targeting intracellular components for lysosomal degradation by autophagy represents a catabolic process that evolutionarily regulates cellular homeostasis. The successful completion of autophagy initiates the engulfment of cytoplasmic
Externí odkaz:
https://doaj.org/article/a394f9ca6c204c218136d7d6e704fab8
Akademický článek
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Publikováno v:
Neural Regeneration Research, Vol 17, Iss 2, Pp 370-377 (2022)
High-frequency spinal cord stimulation (HF-SCS) has been established as an effective therapy for neuropathic pain. However, the analgesic mechanisms involved in HF-SCS remain to be clarified. In our study, adult rat neuropathic pain was induced by sp
Externí odkaz:
https://doaj.org/article/472b1034534249c3a86c93d1899354c7
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Recently, there has been a rapidly expanding interest in a new nanomaterial, graphene quantum dots (GQDs), owing to its profound potential in various advanced applications. At present, the study of GQDs mainly focuses on the new synthesis methods and
Externí odkaz:
https://doaj.org/article/62365e075f464a1db745aac6589f779f
Ultrasmall iron oxide nanoparticles induced ferroptosis via Beclin1/ATG5-dependent autophagy pathway
Publikováno v:
Nano Convergence, Vol 8, Iss 1, Pp 1-15 (2021)
Abstract Iron-based nanoparticles, which could elicit ferroptosis, is becoming a promising new way to inhibit tumor cell growth. Notably, ultrasmall iron oxide nanoparticles (USIONPs) have been found to upregulate the autophagy process in glioblastom
Externí odkaz:
https://doaj.org/article/0b972067281241d38f4c14ed125b8ccd