Zobrazeno 1 - 10
of 752
pro vyhledávání: '"atp sensitive potassium channels"'
Autor:
Allison C. Wexler, Holly Dooge, Sarah El-Meanawy, Elizabeth Santos, Timothy Hacker, Aditya Tewari, Francisco J. Alvarado, Mohun Ramratnam
Publikováno v:
Journal of Molecular and Cellular Cardiology Plus, Vol 9, Iss , Pp 100088- (2024)
The small splice variant of the sulfonylurea receptor protein isoform 2 A (SUR2A-55) targets mitochondria and enhances mitoKATP activity. In male mice the overexpression of this protein promotes cardioprotection, reducing myocardial injury after an i
Externí odkaz:
https://doaj.org/article/356836f448354e3f93dfb563975b6d73
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
Cumulative evidence suggests that ATP-sensitive potassium (KATP) channels act as a key regulator of cerebral blood flow (CBF). This implication seems to be complicated, since KATP channels are expressed in several vascular-related structures such as
Externí odkaz:
https://doaj.org/article/1d1f03268cec448cbb1d90e43f6e3c31
Publikováno v:
Immunity, Inflammation and Disease, Vol 12, Iss 3, Pp n/a-n/a (2024)
Abstract Background Parkinson's disease (PD) is a common neurodegenerative disorder. Microglia‐mediated neuroinflammation has emerged as an involving mechanism at the initiation and development of PD. Activation of adenosine triphosphate (ATP)‐se
Externí odkaz:
https://doaj.org/article/18f5741d6b6140eb940ac58587734998
Autor:
Jovana Rajkovic, Miodrag Peric, Jelena Stanisic, Milos Gostimirovic, Radmila Novakovic, Vladimir Djokic, Snezana Tepavcevic, Jelena Rakocevic, Milica Labudovic-Borovic, Ljiljana Gojkovic-Bukarica
Publikováno v:
Pharmaceuticals, Vol 17, Iss 7, p 857 (2024)
Here we have shown for the first time altered expression of the vascular smooth muscle (VSM) KATP channel subunits in segments of the human internal mammary artery (HIMA) in patients with type-2 diabetes mellitus (T2DM). Functional properties of vasc
Externí odkaz:
https://doaj.org/article/071195b9d38c40ebb21508903db1e1e2
Autor:
Mohamed E. Elangeeb, Imadeldin Elfaki, Ali M. S. Eleragi, Elsadig Mohamed Ahmed, Rashid Mir, Salem M. Alzahrani, Ruqaiah I. Bedaiwi, Zeyad M. Alharbi, Mohammad Muzaffar Mir, Mohammad Rehan Ajmal, Faris Jamal Tayeb, Jameel Barnawi
Publikováno v:
Molecules, Vol 29, Iss 8, p 1904 (2024)
Diabetes mellitus (DM) represents a problem for the healthcare system worldwide. DM has very serious complications such as blindness, kidney failure, and cardiovascular disease. In addition to the very bad socioeconomic impacts, it influences patient
Externí odkaz:
https://doaj.org/article/ffb16e6b0ca044378f5b3b49bbbe5ce8
Publikováno v:
Frontiers in Nutrition, Vol 10 (2023)
BackgroundMigraine is a prevalent neurovascular headache disorder. The link between dietary potassium and blood pressure has been established. We sought to delineate the relationship between dietary potassium intake and the prevalence of migraines.Me
Externí odkaz:
https://doaj.org/article/f5453f0348fa429cba34d236344a27c0
Publikováno v:
Endocrine Connections, Vol 12, Iss 1, Pp 1-11 (2022)
Objective: Lipotoxicity-induced pancreatic β cell-dysfunction results in decreased insulin secretion in response to multiple stimulus. In this study, we i nvestigated the reversible effects of palmitate (PA) or oleate (OA) on insulin secretion and t
Externí odkaz:
https://doaj.org/article/57d23255395f472f865aa955313f3791
Akademický článek
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Autor:
Zhifan Mao, Wenwen Liu, Yunyuan Huang, Tianyue Sun, Keting Bao, Jiali Feng, Alexey Moskalev, Zelan Hu, Jian Li
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 2, Pp 665-677 (2022)
Sulfonylureas are widely used oral anti-diabetic drugs. However, its long-term usage effects on patients’ lifespan remain controversial, with no reports of influence on animal longevity. Hence, the anti-aging effects of chlorpropamide along with gl
Externí odkaz:
https://doaj.org/article/7322716928994ca589edc43563fda553
Akademický článek
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