Zobrazeno 1 - 10
of 3 022
pro vyhledávání: '"astragaloside IV"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract This study investigated the therapeutic effects of astragaloside IV (AST) on spinocerebellar ataxia type 3 (SCA3), also known as Machado-Joseph disease (MJD), a neurodegenerative disorder. Human neuroblastoma SK-N-SH cells expressing mutant
Externí odkaz:
https://doaj.org/article/6c3f7f8be7bd4a0b84758276b51aa4a0
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Immune checkpoint inhibitors (ICIs) are effective agents for tumor immunotherapy. However, their clinical effectiveness is unsatisfactory due to off-target effects and a suppressive immune microenvironment. This study developed a nanodrug de
Externí odkaz:
https://doaj.org/article/190c095085bf45a0a868557c4eec096e
Publikováno v:
Journal of Traditional Chinese Medical Sciences, Vol 11, Iss 3, Pp 340-350 (2024)
Objective: To determine the main components of Astragalus membranaceus (Fisch.) Bge (A. membranaceus, Huang Qi), Astragaloside IV (AIV) and Astragalus polysaccharides (AP), to characterize their properties, evaluate their in vivo efficacy, and to ana
Externí odkaz:
https://doaj.org/article/025f576f73db4bb78e5179887cdaa1a2
Publikováno v:
Botanical Studies, Vol 65, Iss 1, Pp 1-7 (2024)
Abstract Background Astragaloside IV is a main medicinal active ingredient in Astragalus membranaceus Bge. var. mongholicus (Bge.) Hsiao, which is also the key biomarker of A. membranaceus quality. Ethylene has been well-documented to involve in seco
Externí odkaz:
https://doaj.org/article/5e67211f0dec403c92e9458f4e4676e1
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
BackgroundAstragalus mongholicus Bunge [Fabaceae; Astragali radix] (AM), a traditional Chinese medicinal (TCM) botanical drug, has been used for centuries and is gaining growing recognition in medical research for its therapeutic potential. The curre
Externí odkaz:
https://doaj.org/article/715fab96bbe14aafb0bd1a2b0b27eccb
Publikováno v:
Autoimmunity, Vol 57, Iss 1 (2024)
Childhood asthma, a common chronic childhood disease, leads to high mortality and morbidity in the world. Airway smooth muscle cells (ASMCs) is a group of multifunctional cells that has been found to be correlated with the pathogenesis of asthma. Ast
Externí odkaz:
https://doaj.org/article/224d17da27344f5f8a330ab775087589
Autor:
Yuhua Ma, Yuwen Hu, Yilin Ruan, Xiaocheng Jiang, Min Zhao, Yuxin Wang, Yanrong Ke, Manman Shi, Guoyuan Lu
Publikováno v:
Renal Failure, Vol 46, Iss 2 (2024)
The pathogenesis of membranous nephropathy (MN) involves podocyte injury that is attributed to inflammatory responses induced by local immune deposits. Astragaloside IV (AS-IV) is known for its robust anti-inflammatory properties. Here, we investigat
Externí odkaz:
https://doaj.org/article/dd9ef6d9b08244c6b6dd23ba4399d9d1
Autor:
Xiao Wang, Xinting Chen, Yuting Wang, Xinyu He, Lan Li, Xiaodan Wang, Yuting Huang, Guanwei Fan, Jingyu Ni
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
BackgroundHeart failure with preserved ejection fraction (HFpEF) has grown to become the dominant form of heart failure worldwide. However, no unequivocally effective treatment for HFpEF has been identified in clinical trials. In this study, we repor
Externí odkaz:
https://doaj.org/article/bf96e4de8ec4410db026b8cf7405ea77
Publikováno v:
European Journal of Histochemistry, Vol 68, Iss 4 (2024)
Programmed cell death protein-1 (PD-1) inhibitors are increasingly utilized in the treatment of lung cancer (LC). Combination therapy has recently gained popularity in treating LC. This study aimed to assess the efficacy of combining Astragaloside IV
Externí odkaz:
https://doaj.org/article/eda13e9e2fd24675bd933b9c0a535e17
Autor:
JinFang Hao, Xiaoyan Zhang, Ruixian Hu, Xiufeng Lu, Hui Wang, Yuanhong Li, Kai Cheng, Qingshan Li
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Background Astragaloside IV (AST-IV), as an effective active ingredient of Astragalus membranaceus (Fisch.) Bunge. It has been found that AST-IV inhibits the replication of dengue virus, hepatitis B virus, adenovirus, and coxsackievirus B3.
Externí odkaz:
https://doaj.org/article/e41b8acfc29148e3ba6d9fa07b20e082