Zobrazeno 1 - 10
of 2 806
pro vyhledávání: '"associated antigens"'
Publikováno v:
Artificial Cells, Nanomedicine, and Biotechnology, Vol 52, Iss 1, Pp 300-308 (2024)
Lung cancer is a dangerous disease that is lacking in an ideal therapy. Here, we evaluated the anti-lung cancer effect in nude mice of a fully human single-chain antibody (scFv) against the associated antigen 7 transmembrane receptor (Ts7TMR), which
Externí odkaz:
https://doaj.org/article/ae2aabe187b741fe8409b557bab6839b
Autor:
Changlin Yang, Vrunda Trivedi, Kyle Dyson, Tongjun Gu, Kate M. Candelario, Oleg Yegorov, Duane A. Mitchell
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-19 (2024)
Abstract Background The current standard of care treatments for medulloblastoma are insufficient as these do not take tumor heterogeneity into account. Newer, safer, patient-specific treatment approaches are required to treat high-risk medulloblastom
Externí odkaz:
https://doaj.org/article/8684278dd84441a8814e938fc4589449
Publikováno v:
Ultrasonics Sonochemistry, Vol 111, Iss , Pp 107078- (2024)
Tumor biomarkers play an essential role in immunotherapeutic strategies in cancer treatment, contributing to early diagnosis, patient selection, treatment monitoring, and personalized treatment plans. Despite their importance in cancer care, circulat
Externí odkaz:
https://doaj.org/article/fd3a82aeeeee4256bfac5627e33096ca
Autor:
Zhen Xu, Ze-Xiu Xiao, Jing Wang, Hao-Wei Qiu, Fei Cao, Shi-Qiang Zhang, Yuan-Dong Xu, Han-Qi Lei, Heng Xia, Yun-Ru He, Gao-Feng Zha, Jun Pang
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
Prostate cancer (PCa) is characterized as a “cold tumor” with limited immune responses, rendering the tumor resistant to immune checkpoint inhibitors (ICI). Therapeutic messenger RNA (mRNA) vaccines have emerged as a promising strategy to overcom
Externí odkaz:
https://doaj.org/article/cbd29fbd3fa84d29b98360b4a443d88f
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 6, Pp 2361-2377 (2024)
T cell-redirecting bispecific antibodies are specifically designed to bind to tumor-associated antigens, thereby engaging with CD3 on the T cell receptor. This linkage between tumor cells and T cells actively triggers T cell activation and initiates
Externí odkaz:
https://doaj.org/article/b5df7d48427c435599d3d70f4b830d2f
Publikováno v:
Onco, Vol 4, Iss 2, Pp 87-100 (2024)
Lung cancer (LC) is one of the leading causes of cancer-related deaths. Pulmonary nodules are one of the risk factors, and their discovery rate has been increasing due to enhanced performance of chest CT scans, but more than 90% are non-malignant, ca
Externí odkaz:
https://doaj.org/article/1aa2966e2fc24c338e9d89c53478eaf6
Autor:
Yifan Cheng, Qing Li, Guiying Sun, Tiandong Li, Yuanlin Zou, Hua Ye, Keyan Wang, Jianxiang Shi, Peng Wang
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract The purpose of this study was to identify novel autoantibodies against tumor-associated antigens (TAAs) and explore a diagnostic panel for Ovarian cancer (OC). Enzyme-linked immunosorbent assay was used to detect the expression of five anti-
Externí odkaz:
https://doaj.org/article/c20ce9aca0b44a569c1445451da4792d
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Tumors are mostly characterized by genetic instability, as result of mutations in surveillance mechanisms, such as DNA damage checkpoint, DNA repair machinery and mitotic checkpoint. Defect in one or more of these mechanisms causes additive
Externí odkaz:
https://doaj.org/article/fbff5259b984451397a31a559e3f4eac
Publikováno v:
Translational Oncology, Vol 51, Iss , Pp 102176- (2025)
Neuroblastoma is an embryonic tumour originating from neural crest cells and accounts for nearly 15 % of all childhood cancer deaths. Despite the implementation of intense multimodal therapy for neuroblastoma, half of the high-risk cohort will relaps
Externí odkaz:
https://doaj.org/article/724608ac55a848209895a980b4e9a6f6
Autor:
Silvia Brugiapaglia, Sara Bulfamante, Claudia Curcio, Maddalena Arigoni, Raffaele Calogero, Lisa Bonello, Elisa Genuardi, Rosella Spadi, Maria Antonietta Satolli, Donata Campra, Daniele Giordano, Paola Cappello, Francesca Cordero, Francesco Novelli
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionPancreatic Ductal Adenocarcinoma (PDA) is one of the most aggressive malignancies with a 5-year survival rate of 13%. Less than 20% of patients have a resectable tumor at diagnosis due to the lack of distinctive symptoms and reliable biom
Externí odkaz:
https://doaj.org/article/76a09af1172e4c0f8aa82fe17684894b