Zobrazeno 1 - 10
of 938
pro vyhledávání: '"aryl hydrocarbon receptor (AhR)"'
Autor:
Sarah E. Morgan, Lisa A. DeLouise
Publikováno v:
Eco-Environment & Health, Vol 3, Iss 3, Pp 347-354 (2024)
This project reports on the use of a novel nanomembrane filtering technology to isolate and analyze the bioactivity of microplastic (MP)-containing debris from Lake Ontario water samples. Environmental MPs are a complex mixture of polymers and sorbed
Externí odkaz:
https://doaj.org/article/416d4b64bc5c49cb8e4931134b8621f3
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-13 (2024)
Abstract 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a persistent environmental contaminant that disrupts hepatic function leading to steatotic liver disease (SLD)-like pathologies, such as steatosis, steatohepatitis, and fibrosis. These effects ar
Externí odkaz:
https://doaj.org/article/fb48d6e31421443c87289a33eda499ff
Autor:
Mina Rahmati, Mojtaba Zare Ebrahimabad, Alale Langari, Ali Najafi, Shohreh Taziki, Alireza Norouzi, Mehrdad Teimoorian, Milad Khorasani, Saeed Mohammadi
Publikováno v:
Immuno, Vol 4, Iss 2, Pp 159-171 (2024)
Chronic hepatitis B (CHB) poses treatment challenges, with treatment response and disease outcome often determined by the immune response, particularly mononuclear phagocytes. Monocytes can differentiate into various subpopulations influenced by AHR.
Externí odkaz:
https://doaj.org/article/9347c79f21a94382972da35e101d24cd
Autor:
Chuan Chen, Zheng Cao, Hehua Lei, Cui Zhang, Mengjing Wu, Shaohua Huang, Xinzhi Li, Denghui Xie, Maili Liu, Limin Zhang, Gang Chen
Publikováno v:
Advanced Science, Vol 11, Iss 36, Pp n/a-n/a (2024)
Abstract Microbial tryptophan (Trp) metabolites acting as aryl hydrocarbon receptor (AhR) ligands are shown to effectively improve metabolic diseases via regulating microbial community. However, the underlying mechanisms by which Trp metabolites amel
Externí odkaz:
https://doaj.org/article/29b33e8d031149b48ee19f82461f374f
Autor:
Natalija Jonić, Ivan Koprivica, Stavroula G. Kyrkou, Vasileios-Panagiotis Bistas, Christos Chatzigiannis, Nataša Radulović, Ivan Pilipović, Andjelina Jovanović, Milan B. Jovanović, Mirjana Dimitrijević, Andreas G. Tzakos, Ivana Stojanović
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Type 1 diabetes (T1D) is an autoimmune disease with a strong chronic inflammatory component. One possible strategy for the treatment of T1D is to stimulate the regulatory arm of the immune response, i.e. to promote the function of tolerogenic dendrit
Externí odkaz:
https://doaj.org/article/11b51184e3184bd1b78ab93ef5a4d033
Publikováno v:
Journal of Cutaneous Immunology and Allergy, Vol 7 (2024)
Background: Tapinarof is a nonsteroidal, topical, aryl hydrocarbon receptor agonist. Tapinarof has been shown to be efficacious and have acceptable safety profile in the treatment of atopic dermatitis (AD).Objective: We sought to evaluate the improve
Externí odkaz:
https://doaj.org/article/ca3f5f18158f423495f802d4db1d2eb1
Autor:
Wanqian Guo, Chenping Kang, Xiaoxia Wang, Haoran Zhang, Lilan Yuan, Xuetao Wei, Qianqian Xiao, Weidong Hao
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 274, Iss , Pp 116193- (2024)
Chlorocholine chloride (CCC) is a plant growth regulator used worldwide that is detectable in cereals, fruits and animal products. The health effects of CCC exposure have raised public concern. Our previous research showed that CCC exposure decreased
Externí odkaz:
https://doaj.org/article/f3ea1c57778d42bfb4d903b987789a16
Publikováno v:
Pharmaceutical Biology, Vol 61, Iss 1, Pp 1082-1093 (2023)
AbstractContext Aryl hydrocarbon receptor (AhR) agonists are potential therapeutic agents for ulcerative colitis (UC). Indirubin (IDR), which is a natural AhR ligand approved for leukemia treatment, ameliorates dextran sulfate sodium (DSS)-induced co
Externí odkaz:
https://doaj.org/article/7959cf9810e34004b272385162b47c29
Autor:
Colleen S. Curran, Jeffrey B. Kopp
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-19 (2023)
Abstract Early-stage detection of chronic kidney diseases (CKD) is important to treatment that may slow and occasionally halt CKD progression. CKD of diverse etiologies share similar histologic patterns of glomerulosclerosis, tubular atrophy, and int
Externí odkaz:
https://doaj.org/article/0a73bbab43da45aeb47f43cf46d5e408
Publikováno v:
Biomedicines, Vol 12, Iss 8, p 1905 (2024)
The vast majority of gastric cancer (GC) cases are adenocarcinomas including intestinal and diffuse GC. The incidence of diffuse GC, often associated with poor overall survival, has constantly increased in Western countries. Epidemiological studies h
Externí odkaz:
https://doaj.org/article/481ab5886d2143408f1e5c25c4ae5061