Comparison of the Anticancer Effects of Arvanil and Olvanil When Combined with Cisplatin and Mitoxantrone in Various Melanoma Cell Lines—An Isobolographic Analysis

Autor: Paweł Marzęda, Paula Wróblewska-Łuczka, Magdalena Florek-Łuszczki, Małgorzata Drozd, Agnieszka Góralczyk, Jarogniew J. Łuszczki

Publikováno v: International Journal of Molecular Sciences; Volume 23; Issue 22; Pages: 14192

Due to the unique structures of arvanil and olvanil, the drugs combine certain properties of both cannabinoids and vanilloids, which makes them able to stimulate both TPRV1 and CB1 receptors and causes them to be interesting agents in the setting of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f88ad17d97cfc2a83b05be92f7f027f7
https://doi.org/10.3390/ijms232214192

The anandamide membrane transporter and the therapeutic implications of its inhibition

Autor: Natalia Battista, Filomena Fezza, Valeria Gasperi, Mauro Maccarrone

Publikováno v: Therapy. 2:141-150

Endocannabinoids are a new class of lipid mediators that include amides, esters and ethers of long chain polyunsaturated fatty acids. Anandamide (N-arachidonoylethanolamine), the most prominent member of this group together with 2-arachidonoyl glycer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73e44a51f6d9da6dddea7078ab11a549
https://doi.org/10.1586/14750708.2.1.141

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Arvanil and anandamide up-regulate CD36 expression in human peripheral blood mononuclear cells

Autor: Anna Maria Malfitano, Marvin N. Schwalb, Luciano De Petrocellis, Patrizia Gazzerro, Gokce Altay Toruner, Davide Eletto, Maurizio Bifulco, Seema Husain, Pierangelo Orlando, Emilia Vitale, C. Laezza, Alexandra Terskiy

Publikováno v: 16th Symposium on the Cannabinoids of the International Cannabinoid Research Society, Tihany, 2006
info:cnr-pdr/source/autori:A.M. Malfitano, G.A. Toruner, C. Laezza, S. Husain, P. Gazzerro, D. Eletto, P. Orlando, L. De Petrocellis, A. Terskiry, M. Schwalb, E. Vitale, M. Bifulco/congresso_nome:16th Symposium on the Cannabinoids of the International Cannabinoid Research Society,/congresso_luogo:Tihany/congresso_data:2006/anno:2006/pagina_da:/pagina_a:/intervallo_pagine
16th Symposium on the Cannabinoids of the International Cannabinoid Research Society, pp. 169–169, Tihany, Hungary, 2006
info:cnr-pdr/source/autori:A.M. Malfitano, G.A. Toruner, C. Laezza, S. Husain, P. Gazzerro, D. Eletto, P. Orlando, L. De Petrocellis, A. Terskiry, M. Schwalb, E. Vitale, M. Bifulco/congresso_nome:16th Symposium on the Cannabinoids of the International Cannabinoid Research Society/congresso_luogo:Tihany, Hungary/congresso_data:2006/anno:2006/pagina_da:169/pagina_a:169/intervallo_pagine:169–169
Immunology letters 109 (2007): 145–154. doi:10.1016/j.imlet.2007.02.004
info:cnr-pdr/source/autori:Malfitano AM, Toruner GA, Gazzerro P, Laezza C, Husain S, Eletto D, Orlando P, De Petrocellis L, Terskiy A, Schwalb M, Vitale E, Bifulco M./titolo:Arvanil and anandamide up-regulate CD36 expression in human peripheral blood mononuclear cells./doi:10.1016%2Fj.imlet.2007.02.004/rivista:Immunology letters/anno:2007/pagina_da:145/pagina_a:154/intervallo_pagine:145–154/volume:109
Immunology letters 15 (2007): 145–154. doi:10.1016/j.imlet.2007.02.004
info:cnr-pdr/source/autori:Malfitano A M., Toruner G A., Gazzerro P., Laezza C.,Husain S., Eletto D., Orlando P., De Petrocellis L., Terskiy A.,Schwalb M., Vitale E., Bifulco M./titolo:Arvanil and anandamideup-regulate CD36 expression in human peripheral blood mononuclearcells./doi:10.1016%2Fj.imlet.2007.02.004/rivista:Immunology letters/anno:2007/pagina_da:145/pagina_a:154/intervallo_pagine:145–154/volume:15

In this study we analysed the regulation of gene expression by arvanil and anandamide in human peripheral blood mononuclear cells (PBMCs) to clarify their immunosuppressive properties. PBMCs were activated, leading to CD36 down regulation, that was n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a52965d37ab5be9af2b885fcbd2ed20e
http://www.cnr.it/prodotto/i/106373

Palmitoylethanolamide inhibits the expression of fatty acid amide hydrolase and enhances the anti-proliferative effect of anandamide in human breast cancer cells

Autor: Di Marzo V., Melck D., Orlando P., Bisogno T., Zagoory O., Bifulco M., Vogel Z., De Petrocellis L.

Publikováno v: Biochemical journal (Lond., 1984) 358 (2001): 249–255. doi:10.1042/0264-6021:3580249
info:cnr-pdr/source/autori:Di Marzo V., Melck D., Orlando P., Bisogno T., Zagoory O., Bifulco M., Vogel Z., De Petrocellis L./titolo:Palmitoylethanolamide inhibits the expression of fatty acid amide hydrolase and enhances the anti-proliferative effect of anandamide in human breast cancer cells/doi:10.1042%2F0264-6021:3580249/rivista:Biochemical journal (Lond., 1984)/anno:2001/pagina_da:249/pagina_a:255/intervallo_pagine:249–255/volume:358

Palmitoylethanolamide (PEA) has been shown to act in synergy with anandamide (arachidonoylethanolamide; AEA), an endogenous agonist of cannabinoid receptor type 1 (CB(1)). This synergistic effect was reduced by the CB(2) cannabinoid receptor antagoni

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::156b5b3c9596b3846a7df48b82bbff5d
https://pubmed.ncbi.nlm.nih.gov/11485574