Výsledky vyhledávání - "arrhythmic risk"

Akademický článek

Effects of ranolazine on the arrhythmic substrate in hypertrophic cardiomyopathy

Autor: James A. Coleman, Ruben Doste, Matteo Beltrami, Alessia Argirò, Raffaele Coppini, Iacopo Olivotto, Betty Raman, Alfonso Bueno-Orovio

Publikováno v: Frontiers in Pharmacology, Vol 15 (2024)

Introduction: Hypertrophic cardiomyopathy (HCM) is a leading cause of lethal arrhythmias in the young. Although the arrhythmic substrate has been hypothesised to be amenable to late Na+ block with ranolazine, the specific mechanisms are not fully und

Externí odkaz: https://doaj.org/article/88b4d6cbdf584b0ebb2bf0f0d16c0069

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Akademický článek

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Akademický článek

Elevated Interleukin‐6 Levels Are Associated With an Increased Risk of QTc Interval Prolongation in a Large Cohort of US Veterans

Autor: Pietro Enea Lazzerini, Michael Cupelli, Alessandra Cartocci, Iacopo Bertolozzi, Viola Salvini, Riccardo Accioli, Fabio Salvadori, Tommaso Marzotti, Decoroso Verrengia, Gabriele Cevenini, Stefania Bisogno, Maurizio Bicchi, Giovanni Donati, Sciaila Bernardini, Franco Laghi‐Pasini, Maurizio Acampa, Pier Leopoldo Capecchi, Nabil El‐Sherif, Mohamed Boutjdir

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 4 (2024)

Background Although accumulating data indicate that IL‐6 (interleukin‐6) can promote heart rate‐corrected QT interval (QTc) prolongation via direct and indirect effects on cardiac electrophysiology, current evidence comes from basic investigati

Externí odkaz: https://doaj.org/article/7353815fe328412497ff8fa8f37b7e2a

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Akademický článek

Editorial: The wide spectrum of ventricular arrhythmias: from out-of-hospital cardiac arrest to advanced in-hospital treatment

Autor: Enrico Baldi, Hanno L. Tan, Veronica Dusi, Roberto Rordorf, Alessandro Zorzi, Simone Savastano

Publikováno v: Frontiers in Cardiovascular Medicine, Vol 11 (2024)

Externí odkaz: https://doaj.org/article/14e9a23f5c7442ce99b963281401edb7

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Akademický článek

Genetic spectrum of familial and sporadic dilated cardiomyopathy: arrhythmic phenotypes associated with mutations in the lamin A/C (LMNA) gene

Autor: T. G. Vaikhanskaya, L. N. Sivitskaya, T. V. Kurushka, A. D. Liaudanski, N. G. Danilenko

Publikováno v: Евразийский Кардиологический Журнал, Vol 0, Iss 2, Pp 26-37 (2023)

Purpose. To study the diagnostic value of cascade family screening and the spectrum of genetic variants in patients with familial and sporadic DCM, assess clinical outcomes and comparative analysis of 5-year event-free survival.Materials and methods.

Externí odkaz: https://doaj.org/article/f8d78ffeb2f8466faee925185dd3f873

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Akademický článek

Missense and Non-Missense Lamin A/C Gene Mutations Are Similarly Associated with Major Arrhythmic Cardiac Events: A 20-Year Single-Centre Experience

Publikováno v: Biomedicines, Vol 12, Iss 6, p 1293 (2024)

Arrhythmic risk stratification in patients with Lamin A/C gene (LMNA)-related cardiomyopathy influences clinical decisions. An implantable cardioverter defibrillator (ICD) should be considered in patients with an estimated 5-year risk of malignant ve

Externí odkaz: https://doaj.org/article/b647d6fc10dd4129b0e3ea8b1c068f9d

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Akademický článek

Scenarios for Increasing, Decreasing and Stability of Tpe/QT Ratio (Simulation Study)

Autor: Natalia V. Arteyeva, Jan E. Azarov

Publikováno v: International Journal of Biomedicine, Vol 12, Iss 4, Pp 535-538 (2022)

The objective of this simulation was to study the physiological meaning of the novel index for arrhythmic risk stratification – Tpe/QT ratio (the interval from the peak to the end of the T-wave (Tpe) on electrocardiogram divided by QT interval). M

Externí odkaz: https://doaj.org/article/ec27bffa07dc438883bc2252f991f09f

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Akademický článek

Follow-up of CRT-D patients downgraded to CRT-P at the time of generator exchange

Autor: Simon Martin Frey, Roman Brenner, Dominic A. Theuns, Naeem Al-Shoaibi, Richard J. Crawley, Peter Ammann, Christian Sticherling, Michael Kühne, Stefan Osswald, Beat Schaer

Publikováno v: Frontiers in Cardiovascular Medicine, Vol 10 (2023)

BackgroundSome patients with cardiac resynchronisation therapy (CRT) experience super-response (LVEF improvements to ≥50%). At generator exchange (GE), downgrading (DG) from CRT-defibrillator (CRT-D) to CRT-pacemaker (CRT-P) could be an option for

Externí odkaz: https://doaj.org/article/542713ebd5ed48e7917ccce9145ecd39

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Akademický článek

Machine learning analysis of complex late gadolinium enhancement patterns to improve risk prediction of major arrhythmic events

Autor: Hassan A. Zaidi, Richard E. Jones, Daniel J. Hammersley, Suzan Hatipoglu, Gabriel Balaban, Lukas Mach, Brian P. Halliday, Pablo Lamata, Sanjay K. Prasad, Martin J. Bishop

Publikováno v: Frontiers in Cardiovascular Medicine, Vol 10 (2023)

BackgroundMachine learning analysis of complex myocardial scar patterns affords the potential to enhance risk prediction of life-threatening arrhythmia in stable coronary artery disease (CAD).ObjectiveTo assess the utility of computational image anal

Externí odkaz: https://doaj.org/article/df87b301f63c4399b3cc9e06b3774775

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