Zobrazeno 1 - 10
of 92
pro vyhledávání: '"arrb1"'
Autor:
Luana Abballe, Vincenzo Alfano, Celeste Antonacci, Maria Giuseppina Cefalo, Antonella Cacchione, Giada Del Baldo, Marco Pezzullo, Agnese Po, Marta Moretti, Angela Mastronuzzi, Enrico De Smaele, Elisabetta Ferretti, Franco Locatelli, Evelina Miele
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Development of the cerebellum is characterized by rapid proliferation of cerebellar granule cell precursors (GCPs) induced by paracrine stimulation of Sonic hedgehog (Shh) signaling from Purkinje cells, in the external granular layer (EGL). Then, gra
Externí odkaz:
https://doaj.org/article/f757549346b04ac7b13acf5e6cf7ad88
Autor:
Kenneth Chappell, Abd El Kader Ait Tayeb, Romain Colle, Jérôme Bouligand, Khalil El-Asmar, Florence Gressier, Séverine Trabado, Denis Joseph David, Bruno Feve, Laurent Becquemont, Emmanuelle Corruble, Céline Verstuyft
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Introduction: β-arrestin 1, a protein encoded by ARRB1 involved in receptor signaling, is a potential biomarker for the response to antidepressant drug (ATD) treatment in depression. We examined ARRB1 genetic variants for their association with resp
Externí odkaz:
https://doaj.org/article/71a368eefff84210890914708d949ec2
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Background: β-arrestin1 (ARRB1), was originally identified as a multifunctional adaptor protein. Although ARRB1 has recently been shown to also play an important role in tumor growth, metastasis, inflammation, and immunity, its relationship with dis
Externí odkaz:
https://doaj.org/article/cc585af9889d47c9aa256b22c7df15da
Autor:
Evelina Miele, Agnese Po, Angela Mastronuzzi, Andrea Carai, Zein Mersini Besharat, Natalia Pediconi, Luana Abballe, Giuseppina Catanzaro, Claudia Sabato, Enrico De Smaele, Gianluca Canettieri, Lucia Di Marcotullio, Alessandra Vacca, Antonello Mai, Massimo Levrero, Stefan M. Pfister, Marcel Kool, Felice Giangaspero, Franco Locatelli, Elisabetta Ferretti
Publikováno v:
Molecular Oncology, Vol 15, Iss 2, Pp 523-542 (2021)
Persistent mortality rates of medulloblastoma (MB) and severe side effects of the current therapies require the definition of the molecular mechanisms that contribute to tumor progression. Using cultured MB cancer stem cells and xenograft tumors gene
Externí odkaz:
https://doaj.org/article/3ec33b21a6324dbd9f6e0a27e592e22c
Akademický článek
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Akademický článek
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Akademický článek
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Autor:
Yasser AbdElsattar Elghobashy, Mohamed FA. Assar, Asmaa A. Mahmoud, Abdel Monem A Eltorgoman, Saher Elmasry
Publikováno v:
Biochemistry and Biophysics Reports, Vol 24, Iss , Pp 100836- (2020)
Background: β-thalassemia is an inherited hemoglobinopathy resulting in quantitative changes in the β-globin chain. Understanding the molecular basis of that disorder requires studying the expression of genes controlling the pathways that affect th
Externí odkaz:
https://doaj.org/article/3c74fcc90c174cbb9db8df76b18cb719
Autor:
Evelina Miele, Agnese Po, Federica Begalli, Laura Antonucci, Angela Mastronuzzi, Carlo Efisio Marras, Andrea Carai, Danilo Cucchi, Luana Abballe, Zein Mersini Besharat, Giuseppina Catanzaro, Paola Infante, Lucia Di Marcotullio, Gianluca Canettieri, Enrico De Smaele, Isabella Screpanti, Franco Locatelli, Elisabetta Ferretti
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-12 (2017)
Abstract Background Aberrant Sonic Hedgehog/Gli (Hh/Gli) signaling pathway is a critical regulator of Sonic hedgehog medulloblastoma (SHH-MB). Cancer stem cells (CSCs), thought to be largely responsible for tumor initiation, maintenance, disseminatio
Externí odkaz:
https://doaj.org/article/b6b1f6c9e3fc447a83388b129c8c3c64
Autor:
Abballe, L., Alfano, V., Antonacci, C., Cefalo, M. G., Cacchione, A., Del Baldo, G., Pezzullo, M., Po, A., Moretti, M., Mastronuzzi, A., De Smaele, E., Ferretti, E., Locatelli, Franco, Miele, E.
Publikováno v:
Frontiers in Cell and Developmental Biology. 11
Development of the cerebellum is characterized by rapid proliferation of cerebellar granule cell precursors (GCPs) induced by paracrine stimulation of Sonic hedgehog (Shh) signaling from Purkinje cells, in the external granular layer (EGL). Then, gra