Zobrazeno 1 - 10
of 377
pro vyhledávání: '"areg"'
Publikováno v:
Biologics: Targets & Therapy, Vol Volume 18, Pp 273-284 (2024)
Wenbing Zhang,1,* Wenjuan Zhang,2,* Chenling Tang,3,4,* Yan Hu,5 Ke Yi,5 Xiaohui Xu,3– 5 Zhihua Chen3,4 1Department of Gastrointestinal Surgery, Anqing First People’s Hospital Affiliated to Anhui Medical University, Anqing, Anhui, 246
Externí odkaz:
https://doaj.org/article/eef36319035c4c54a9b99d02f8d5fcd3
Autor:
Ma, Ruihua 1, ∗, Prigge, Andrew D. 2, Ortiz Serrano, Tatiana P. 1, Cheng, Yuan 1, Davis, Jennifer M. 1, Lou, Karen F. 1, Wood, Walter A. 1, Do, Hanh Chi 1, Ren, Ziyou 4, Fulcer, McKenzie M. 1, Lotesto, Mary J. 1, Singer, Benjamin D. 1, Coates, Bria M. 2, Ridge, Karen M. 1, 3, 5, ∗∗
Publikováno v:
In Cell Reports 24 December 2024 43(12)
Autor:
John D. Mason, Ewan Marks, Shih‐Jung Fan, Kristie McCormick, Clive Wilson, Adrian L. Harris, Freddie C. Hamdy, Chris Cunningham, Deborah C. I. Goberdhan
Publikováno v:
Journal of Extracellular Vesicles, Vol 13, Iss 6, Pp n/a-n/a (2024)
Abstract Exosomes are secreted vesicles made intracellularly in the endosomal system. We have previously shown that exosomes are not only made in late endosomes, but also in recycling endosomes marked by the monomeric G‐protein Rab11a. These vesicl
Externí odkaz:
https://doaj.org/article/7e95800ddaf04b45a7772cc3e250af9b
Autor:
Daniel Uysal, Blerta Thaqi, Alexander Fierek, David Jurgowski, Zoran V. Popovic, Fabian Siegel, Maurice Stephan Michel, Philipp Nuhn, Thomas Stefan Worst, Philipp Erben, Katja Nitschke
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionMuscle invasive bladder cancer (MIBC) remains a prevalent cancer with limited therapeutic options, obviating the need for innovative therapies. The epidermal growth factor receptor (EGFR) is a linchpin in tumor progression and presents a
Externí odkaz:
https://doaj.org/article/f99abe57e02c45058530681e62a58470
Autor:
Jasmine Ebott, Julia McAdams, Chloe Kim, Corrine Jansen, Morgan Woodman, Payton De La Cruz, Christoph Schrol, Jennifer Ribeiro, Nicole James
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
High grade serous ovarian cancer (HGSOC) is a lethal gynecologic malignancy in which chemoresistant recurrence rates remain high. Furthermore, HGSOC patients have demonstrated overall low response rates to clinically available immunotherapies. Amphir
Externí odkaz:
https://doaj.org/article/d01e7a6f755d4ee7a0e6d60fa3f162dc
Autor:
Man-Huan Xiao, Sihan Wu, Peishi Liang, Dong Ma, Jiang Zhang, Huadong Chen, Zhihai Zhong, Juncheng Liu, Hong Jiang, Xuyang Feng, Zhenhua Luo
Publikováno v:
EBioMedicine, Vol 103, Iss , Pp 105138- (2024)
Summary: Background: Biliary atresia (BA) is a neonatal fibro-inflammatory cholangiopathy with ductular reaction as a key pathogenic feature predicting poor survival. Mucosal-associated invariant T (MAIT) cells are enriched in human liver and display
Externí odkaz:
https://doaj.org/article/2fb97e6aaa9c486bbc6723eb3507d4f3
Autor:
Takashi Nakanishi, Yu-ichiro Koma, Shoji Miyako, Rikuya Torigoe, Hiroki Yokoo, Masaki Omori, Keitaro Yamanaka, Nobuaki Ishihara, Shuichi Tsukamoto, Takayuki Kodama, Mari Nishio, Manabu Shigeoka, Hiroshi Yokozaki, Yoshihiro Kakeji
Publikováno v:
Cells, Vol 13, Iss 20, p 1733 (2024)
Cancer-associated fibroblasts (CAFs) are a key component of the tumor microenvironment and significantly contribute to the progression of various cancers, including esophageal squamous cell carcinoma (ESCC). Our previous study established a direct co
Externí odkaz:
https://doaj.org/article/e88aac8cdec644a4ad84ca048592f162
Autor:
Bichun Guo, Sainan Zhang, Shanshan Wang, Huidan Zhang, Junshun Fang, Nannan Kang, Xin Zhen, Yang Zhang, Jidong Zhou, Guijun Yan, Haixiang Sun, Lijun Ding, Chuanming Liu
Publikováno v:
Reproductive Biology and Endocrinology, Vol 21, Iss 1, Pp 1-15 (2023)
Abstract Background With advanced maternal age, abnormalities during oocyte meiosis increase significantly. Aneuploidy is an important reason for the reduction in the quality of aged oocytes. However, the molecular mechanism of aneuploidy in aged ooc
Externí odkaz:
https://doaj.org/article/12d21e7e539a4cd4b6062fa7607205e6
Autor:
Piotr Popławski, Weronika Zarychta-Wiśniewska, Anna Burdzińska, Joanna Bogusławska, Anna Adamiok-Ostrowska, Karolina Hanusek, Beata Rybicka, Alex Białas, Helena Kossowska, Roksana Iwanicka-Nowicka, Marta Koblowska, Leszek Pączek, Agnieszka Piekiełko-Witkowska
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Background Advanced renal cell carcinoma (RCC) is therapeutically challenging. RCC progression is facilitated by mesenchymal stem/stromal cells (MSCs) that exert remarkable tumor tropism. The specific mechanisms mediating MSCs’ migration t
Externí odkaz:
https://doaj.org/article/830552eccf1f432e9f690d207d53599c
Autor:
Cynthia M Simbulan-Rosenthal, Nusrat Islam, Yogameenakshi Haribabu, Ryyan Alobaidi, Azadeh Shalamzari, Garrett Graham, Li-Wei Kuo, Peter Sykora, Dean S Rosenthal
Publikováno v:
Cells, Vol 13, Iss 9, p 777 (2024)
CD133, a cancer stem cell (CSC) marker in tumors, including melanoma, is associated with tumor recurrence, chemoresistance, and metastasis. Patient-derived melanoma cell lines were transduced with a Tet-on vector expressing CD133, generating doxycycl
Externí odkaz:
https://doaj.org/article/cb5b4feb94cf4aa5aee837c60e98f7a8