Zobrazeno 1 - 10
of 111
pro vyhledávání: '"aram megighian"'
Autor:
Giulio Maria Menti, Matteo Bruzzone, Mauro Agostino Zordan, Patrizia Visentin, Andrea Drago, Marco dal Maschio, Aram Megighian
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Animals’ ability to orient and navigate relies on selecting an appropriate motor response based on the perception and integration of the environmental information. This is the case, for instance, of the optokinetic response (OKR) in Drosop
Externí odkaz:
https://doaj.org/article/f1b85721c9314dbb98e73636cd5fde69
Autor:
Giorgia D'Este, Federico Fabris, Marco Stazi, Chiara Baggio, Morena Simonato, Aram Megighian, Michela Rigoni, Samuele Negro, Cesare Montecucco
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 1, p e0011825 (2024)
Snake envenoming is a major, but neglected, tropical disease. Among venomous snakes, those inducing neurotoxicity such as kraits (Bungarus genus) cause a potentially lethal peripheral neuroparalysis with respiratory deficit in a large number of peopl
Externí odkaz:
https://doaj.org/article/7d0699b5e13742ca99cd4b5b029726c6
Autor:
Caterina Marchioretti, Giulia Zanetti, Marco Pirazzini, Gaia Gherardi, Leonardo Nogara, Roberta Andreotti, Paolo Martini, Lorenzo Marcucci, Marta Canato, Samir R. Nath, Emanuela Zuccaro, Mathilde Chivet, Cristina Mammucari, Marco Pacifici, Anna Raffaello, Rosario Rizzuto, Andrea Mattarei, Maria A. Desbats, Leonardo Salviati, Aram Megighian, Gianni Sorarù, Elena Pegoraro, Elisa Belluzzi, Assunta Pozzuoli, Carlo Biz, Pietro Ruggieri, Chiara Romualdi, Andrew P. Lieberman, Gopal J. Babu, Marco Sandri, Bert Blaauw, Manuela Basso, Maria Pennuto
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Marchioretti and colleagues show that in the skeletal muscle of SBMA mice and patients there is an early, but reversible alteration of expression of genes involved in muscle contraction and of mitochondrial respiration, followed by accumulation of ca
Externí odkaz:
https://doaj.org/article/82a8527dca0543cd91761ed8387c3654
Autor:
Samuele Negro, Fabio Lauria, Marco Stazi, Toma Tebaldi, Giorgia D’Este, Marco Pirazzini, Aram Megighian, Francesca Lessi, Chiara M. Mazzanti, Gabriele Sales, Chiara Romualdi, Silvia Fillo, Florigio Lista, James N. Sleigh, Andrew P. Tosolini, Giampietro Schiavo, Gabriella Viero, Michela Rigoni
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-22 (2022)
Abstract Regeneration of the neuromuscular junction (NMJ) leverages on extensive exchange of factors released from motor axon terminals (MATs), muscle fibers and perisynaptic Schwann cells (PSCs), among which hydrogen peroxide (H2O2) is a major pro-r
Externí odkaz:
https://doaj.org/article/26994f99fdf54e9a92efdf648b2d851d
Autor:
Federico Fabris, Stefano Varani, Marika Tonellato, Ivica Matak, Petra Šoštarić, Patrik Meglić, Matteo Caleo, Aram Megighian, Ornella Rossetto, Cesare Montecucco, Marco Pirazzini
Publikováno v:
JCI Insight, Vol 8, Iss 11 (2023)
Cephalic tetanus (CT) is a severe form of tetanus that follows head wounds and the intoxication of cranial nerves by tetanus neurotoxin (TeNT). Hallmarks of CT are cerebral palsy, which anticipates the spastic paralysis of tetanus, and rapid evolutio
Externí odkaz:
https://doaj.org/article/395ac61e128f4db1a549005bf0738965
Autor:
Federica De Lazzari, Francesco Agostini, Nicoletta Plotegher, Michele Sandre, Elisa Greggio, Aram Megighian, Luigi Bubacco, Federica Sandrelli, Alexander J. Whitworth, Marco Bisaglia
Publikováno v:
Neurobiology of Disease, Vol 176, Iss , Pp 105941- (2023)
The protein DJ-1 is mutated in rare familial forms of recessive Parkinson's disease and in parkinsonism accompanied by amyotrophic lateral sclerosis symptoms and dementia. DJ-1 is considered a multitasking protein able to confer protection under vari
Externí odkaz:
https://doaj.org/article/3afcbe9bdd464d299fad6c0178bc02f6
Autor:
Matteo Bruzzone, Enrico Chiarello, Marco Albanesi, Maria Elena Miletto Petrazzini, Aram Megighian, Claudia Lodovichi, Marco dal Maschio
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Optical recordings of neuronal activity at cellular resolution represent an invaluable tool to investigate brain mechanisms. Zebrafish larvae is one of the few model organisms where, using fluorescence-based reporters of the cell activity, i
Externí odkaz:
https://doaj.org/article/95c312c8227c47b0b74ed7d82899e76b
Autor:
Sandro Malacrida, Federica De Lazzari, Simona Mrakic-Sposta, Alessandra Vezzoli, Mauro A. Zordan, Marco Bisaglia, Giulio Maria Menti, Nicola Meda, Giovanni Frighetto, Gerardo Bosco, Tomas Dal Cappello, Giacomo Strapazzon, Carlo Reggiani, Maristella Gussoni, Aram Megighian
Publikováno v:
Biology Open, Vol 11, Iss 6 (2022)
During recent decades, model organisms such as Drosophila melanogaster have made it possible to study the effects of different environmental oxygen conditions on lifespan and oxidative stress. However, many studies have often yielded controversial re
Externí odkaz:
https://doaj.org/article/69e57848420949889b3d21d0c547c214
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
The central complex (CX) is a neural structure located on the midline of the insect brain that has been widely studied in the last few years. Its role in navigation and goal-oriented behaviors resembles those played by the basal ganglia in mammals. H
Externí odkaz:
https://doaj.org/article/3c17e584388246b390a039fe90102642
Autor:
Nina Strah, Giulia Romano, Clelia Introna, Raffaella Klima, Marta Marzullo, Laura Ciapponi, Aram Megighian, Monica Nizzardo, Fabian Feiguin
Publikováno v:
BMC Biology, Vol 18, Iss 1, Pp 1-13 (2020)
Abstract Background The ribonuclear protein TDP-43 has been implicated in the pathophysiology of amyotrophic lateral sclerosis (ALS), with genetic mutations being linked to the neurological symptoms of the disease. Though alterations in the intracell
Externí odkaz:
https://doaj.org/article/8342709f5ed845b59ab7ba86eb69f58b