Alox12/15 deficiency exacerbates, while Lipoxin A4 ameliorates hepatic inflammation in murine alcoholic hepatitis

Autor: Queck, Alexander, Fink, Annika F., Sirait-Fischer, Evelyn, Rüschenbaum, Sabrina, Thomas, Dominique, Snodgrass, Ryan G., Geisslinger, Gerd, Baba, Hideo A., Trebicka, Jonel, Zeuzem, Stefan, Weigert, Andreas, Lange, Christian M., Brüne, Bernhard

Publikováno v: Frontiers in Immunology
Queck, A, Fink, A F, Sirait-Fischer, E, Rüschenbaum, S, Thomas, D, Snodgrass, R G, Geisslinger, G, Baba, H A, Trebicka, J, Zeuzem, S, Weigert, A, Lange, C M & Brüne, B 2020, ' Alox12/15 Deficiency Exacerbates, While Lipoxin A 4 Ameliorates Hepatic Inflammation in Murine Alcoholic Hepatitis ', Frontiers in Immunology, vol. 11, 1447 . https://doi.org/10.3389/fimmu.2020.01447

Alcoholism is one of the leading and increasingly prevalent reasons of liver associated morbidity and mortality worldwide. Alcoholic hepatitis (AH) constitutes a severe disease with currently no satisfying treatment options. Lipoxin A4 (LXA4), a 15-l

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http://publikationen.ub.uni-frankfurt.de/files/55463/Bruene_alox12_15.zip