Aptamer-Based Imaging of Polyisoprenoids in the Malaria Parasite

Autor: Flavia M. Zimbres, Emilio F. Merino, Grant J. Butschek, Joshua H. Butler, Frédéric Ducongé, Maria B. Cassera

Publikováno v: Molecules, Vol 29, Iss 1, p 178 (2023)

Dolichols are isoprenoid end-products of the mevalonate and 2C-methyl-D-erythritol-4-phosphate pathways. The synthesis of dolichols is initiated with the addition of several molecules of isopentenyl diphosphate to farnesyl diphosphate. This reaction

Externí odkaz: https://doaj.org/article/0762b8beb3464a489c44762777b2e273

Aptamer-Based Imaging of Polyisoprenoids in the Malaria Parasite.

Autor: Zimbres FM; Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA 30602, USA.; Center for Tropical and Emerging Global Diseases (CTEGD), University of Georgia, Athens, GA 30602, USA., Merino EF; Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA 30602, USA.; Center for Tropical and Emerging Global Diseases (CTEGD), University of Georgia, Athens, GA 30602, USA., Butschek GJ; Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA 30602, USA.; Center for Tropical and Emerging Global Diseases (CTEGD), University of Georgia, Athens, GA 30602, USA., Butler JH; Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA 30602, USA.; Center for Tropical and Emerging Global Diseases (CTEGD), University of Georgia, Athens, GA 30602, USA., Ducongé F; French Atomic Energy Commission (CEA), Fundamental Research Division (DRF), Institute of Biology François Jacob (Jacob), Molecular Imaging Research Center, 92265 Fontenay-aux-Roses, France.; Neurodegenerative Diseases Laboratory, CNRS CEA UMR 9199, 92265 Fontenay-aux-Roses, France.; Paris-Saclay University, 92265 Fontenay-aux-Roses, France., Cassera MB; Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA 30602, USA.; Center for Tropical and Emerging Global Diseases (CTEGD), University of Georgia, Athens, GA 30602, USA.

Publikováno v: Molecules (Basel, Switzerland) [Molecules] 2023 Dec 28; Vol. 29 (1). Date of Electronic Publication: 2023 Dec 28.