Zobrazeno 1 - 10
of 118
pro vyhledávání: '"aptamer technology"'
Autor:
Francesca Motta, Antonio Tonutti, Natasa Isailovic, Angela Ceribelli, Giovanni Costanzo, Stefano Rodolfi, Carlo Selmi, Maria De Santis
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundSystemic sclerosis (SSc) is an autoimmune connective tissue disease that affects multiple organs, leading to elevated morbidity and mortality with limited treatment options. The early detection of organ involvement is challenging as there i
Externí odkaz:
https://doaj.org/article/c2c80fc4ed634906bcd0c0424d68e8e4
Autor:
Lanmei Chen, Arpitha Chikkanna, Isabell Brusius, Suxiang Chen, Nabayet Sbuh, Tao Wang, Rakesh N. Veedu
Publikováno v:
Theranostics
Lateral flow assay (LFA) has made a paradigm shift in the in vitro diagnosis field due to its rapid turnaround time, ease of operation and exceptional affordability. Currently used LFAs predominantly use antibodies. However, the high inter-batch vari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a2e0402c82b053e0ca8ddd3c3afe6e8
http://europepmc.org/articles/PMC8039946
http://europepmc.org/articles/PMC8039946
Akademický článek
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Autor:
Youli Zu
Publikováno v:
Blood science (Baltimore, Md.)
Blood Science, Vol 2, Iss 1, Pp 11-15 (2020)
Blood Science, Vol 2, Iss 1, Pp 11-15 (2020)
Oligonucleotide aptamers are a class of small-molecule ligands. Functionally similar to protein antibodies, aptamers can specifically bind to their targets with high affinity. Biomedical studies have revealed the potential clinical value of aptamer t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fe7ad1d78159c8b123608b464bb8710
http://europepmc.org/articles/PMC8782266
http://europepmc.org/articles/PMC8782266
Publikováno v:
Accounts of chemical research. 55(5)
ConspectusAlthough antibodies are a powerful tool for molecular biology and clinical diagnostics, there are many emerging applications for which nucleic acid-based aptamers can be advantageous. However, generating high-quality aptamers with sufficien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d84ca2c7e60cedc4075e6a712b996fd
https://pubmed.ncbi.nlm.nih.gov/35130439
https://pubmed.ncbi.nlm.nih.gov/35130439
Publikováno v:
Pharmaceutics, Vol 13, Iss 1646, p 1646 (2021)
Pharmaceutics
Pharmaceutics
The use of short oligonucleotide or peptide molecules as target-specific aptamers has recently garnered substantial attention in the field of the detection and treatment of viral infections. Based on their high affinity and high specificity to desire
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97a2886853d41c16ef0e3b7bb986b1da
https://www.mdpi.com/1999-4923/13/10/1646
https://www.mdpi.com/1999-4923/13/10/1646
Autor:
Luoshan Ruan, Xin Li
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Frontiers in Genetics
Frontiers in Genetics
Nucleic acid aptamers are short single-stranded DNA or RNA oligonucleotides selected from a random single-stranded nucleic acid library using systematic evolution of ligands by exponential enrichment technology. To allow them to bind to molecular tar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce82242af99041a337b6e7c1df9e1c13
https://doi.org/10.3389/fgene.2021.683542
https://doi.org/10.3389/fgene.2021.683542
Autor:
Bing Yu, Elizabeth Selvin, Peter Ganz, Adrienne Tin, Jianzhong Ma, Ron C. Hoogeveen, Eric Boerwinkle, Kunihiro Masushita, Gerardo Heiss, David Couper, Morgan E. Grams, Alvaro Alonso, Thomas H. Mosley, Josef Coresh, Natalie Daya, Christie M. Ballantyne, Casey M. Rebholz
Publikováno v:
The Journal of Applied Laboratory Medicine. 4:30-39
Background There is growing interest in the use of multiplexed aptamer-based assays for large-scale proteomic studies. However, the analytic, short- and long-term variation of the measured proteins is largely uncharacterized. Methods We quantified 40
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::706c2a818c31dbc027c47dfb194931c6
https://doi.org/10.1373/jalm.2018.027086
https://doi.org/10.1373/jalm.2018.027086
Autor:
Vamkudoth Koteswara Rao
Publikováno v:
Frontiers in Nanotechnology. 2
Coronaviruses are recognized as causative agents of human diseases worldwide. In Wuhan, China, an outbreak of Severe acute respiratory syndrome novel Coronavirus (SARS-nCoV-2) was reported at the end of December 2019, causing 63 million COVID cases a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::377365c552e05cb47cb92f0085ab1461
Autor:
Aditya Pratap Acharya, Arpana Verma, Ayan Mukherjee, Indrajit Kar, Dipak Dey, Jagan Mohanarao Gali
Publikováno v:
Indian Journal of Animal Research.
Aptamers are ‘nucleic acid antibodies’ that bind to target molecules with high affinity and specificity. The process by which aptamers are selected is called Systematic Evolution of Ligands by Exponential Enrichment (SELEX). A plethora of aptamer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dfac4b333962e457c80b24fe9e889bbd
https://doi.org/10.18805/ijar.b-4304
https://doi.org/10.18805/ijar.b-4304