Zobrazeno 1 - 10
of 1 308
pro vyhledávání: '"apoptosi"'
Autor:
Francesca Favaro, Demi Both, Ingrid A. M. Derks, Marcel Spaargaren, Cristina Muñoz-Pinedo, Eric Eldering
Publikováno v:
Oncogenesis, 12(1):6. Nature Publishing Group
Impairments in protein folding in the endoplasmic reticulum (ER) lead to a condition called ER stress, which can trigger apoptosis via the mitochondrial or the death receptor (extrinsic) pathway. There is controversy concerning involvement of the dea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::033c0b1669f432ff73dc2f2bcfddb811
https://doi.org/10.1038/s41389-023-00450-w
https://doi.org/10.1038/s41389-023-00450-w
Publikováno v:
Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk, Vol 21, Iss 4, Pp 48-57 (2018)
Background and Aim: In traditional medicine and previous studies, Quercus infectoria plants have been suggested as a cancer treatment. The aim of the current study was to investigate the cytotoxic effect of aqueous and hydro alcoholic extracts of Que
Externí odkaz:
https://doaj.org/article/e7dd0002a7c0499ab50d28ce5fe35b39
Autor:
Antonietta Notaro, Marianna Lauricella, Diana Di Liberto, Sonia Emanuele, Michela Giuliano, Alessandro Attanzio, Luisa Tesoriere, Daniela Carlisi, Mario Allegra, Anna De Blasio, Giuseppe Calvaruso, Antonella D'Anneo
Methyl gallate (MG), which is a gallotannin widely found in plants, is a polyphenol used in traditional Chinese phytotherapy to alleviate several cancer symptoms. Our studies provided evidence that MG is capable of reducing the viability of HCT116 co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3658::ce76c5270cf403431c432424b7c52a96
https://hdl.handle.net/10447/596178
https://hdl.handle.net/10447/596178
Ethnopharmacological relevance: Prostate cancer originates from cells inside a gland, which begin to grow out of control. In the world, prostate cancer is the most common cancer in the male population. New therapeutic strategies are needed for this t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d52065b19e651ee7ccff2829f098726
https://hdl.handle.net/10447/578211
https://hdl.handle.net/10447/578211
Autor:
Patricia Gassó, Albert Martínez-Pinteño, Natalia Rodríguez, Santiago Madero, Marta Gómez, Alex G. Segura, Clemente García-Rizo, Constanza Morén, Sergi Mas, Eduard Parellada
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 3
Pages: 2054
Volume 24
Issue 3
Pages: 2054
Current antipsychotics (APs) effectively control positive psychotic symptoms, mainly by blocking dopamine (DA) D2 receptors, but have little effect on negative and cognitive symptoms. Increased glutamate (GLU) release would trigger neurotoxicity, lea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbbed48939d67d2e7a2c45b2541da53f
http://hdl.handle.net/2445/194117
http://hdl.handle.net/2445/194117
Autor:
Roberto Dinami, Luca Pompili, Eleonora Petti, Manuela Porru, Carmen D'Angelo, Serena Di Vito, Angela Rizzo, Virginia Campani, Giuseppe De Rosa, Alejandra Bruna, Violeta Serra, Miguel Mano, Mauro Giacca, Carlo Leonetti, Gennaro Ciliberto, Madalena Tarsounas, Antonella Stoppacciaro, Stefan Schoeftner, Annamaria Biroccio
Publikováno v:
Scientia
Target therapy; Telomeres; Triple-negative breast cancer Terapia dirigida; Telómeros; Cáncer de mama triple negativo Teràpia dirigida; Telòmers; Càncer de mama triple negatiu The telomeric repeat-binding factor 2 (TRF2) is a telomere-capping pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bf7e569b8c02ef147a74da50fa04609
https://hdl.handle.net/11351/9402
https://hdl.handle.net/11351/9402
Autor:
Manzano Muñoz, Albert
[eng] Personalized medicine has emerged to improve cancer treatment beyond classical approaches. The identification of genetic mutations by molecular analyses dominate personalized medicine initiatives promoting clinical benefit, but they often prese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______963::6d47bc062db2c947491909bff364b972
http://hdl.handle.net/2445/193043
http://hdl.handle.net/2445/193043
Autor:
Francesca Favaro, Fedra Luciano-Mateo, Joaquim Moreno-Caceres, Miguel Hernández-Madrigal, Demi Both, Chiara Montironi, Franziska Püschel, Ernest Nadal, Eric Eldering, Cristina Muñoz-Pinedo
Publikováno v:
Cell death & disease, 13(12):1046. Nature Publishing Group
Interleukin-8 (IL-8/CXCL8) is a pro-angiogenic and pro-inflammatory chemokine that plays a role in cancer development. Non-small cell lung carcinoma (NSCLC) produces high amounts of IL-8, which is associated with poor prognosis and resistance to chem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecaab36e158fee612daf1651278027d7
https://doi.org/10.1038/s41419-022-05495-0
https://doi.org/10.1038/s41419-022-05495-0
Autor:
Albert Manzano-Muñoz, José Yeste, María A. Ortega, Fernando Martín, Anna López, Jordi Rosell, Sandra Castro, César Serrano, Josep Samitier, Javier Ramón-Azcón, Joan Montero
Publikováno v:
Scientia
Cancer therapy; Predictive markers; Translational research Terapia del cáncer; Marcadores predictivos; Investigación traslacional Teràpia del càncer; Marcadors predictius; Recerca translacional Precision medicine is starting to incorporate functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab868b9a68650a153294b2c6620a9f0c
https://doi.org/10.1038/s41698-022-00333-0
https://doi.org/10.1038/s41698-022-00333-0
Autor:
Antonello Merlino, Giovanni Gotte, Rachele Campagnari, Domenico Loreto, Federica Calzetti, Ilaria Bettin, Marta Menegazzi
Publikováno v:
International Journal of Biological Macromolecules. 191:560-571
Onconase (ONC) is a monomeric amphibian "pancreatic-type" RNase endowed with remarkable anticancer activity. ONC spontaneously forms traces of a dimer (ONC-D) in solution, while larger amounts can be formed when ONC is lyophilized from mildly acidic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b81b626f9f74eb3c1ea0c88d19a6aefb
https://doi.org/10.1016/j.ijbiomac.2021.09.095
https://doi.org/10.1016/j.ijbiomac.2021.09.095