Zobrazeno 1 - 10
of 132
pro vyhledávání: '"apoE, apolipoprotein E"'
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 7, Pp 1767-1788 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Ischemic stroke is a cerebrovascular disease normally caused by interrupted blood supply to the brain. Ischemia would initiate the cascade reaction consisted of multiple biochemical events in the damaged areas of the brain, where the ischemic cascade
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f69f164eb91d122d8129e948fdf80fcb
http://www.sciencedirect.com/science/article/pii/S2211383520308194
http://www.sciencedirect.com/science/article/pii/S2211383520308194
Akademický článek
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Publikováno v:
Advanced Drug Delivery Reviews
mRNA vaccines have evolved from being a mere curiosity to emerging as COVID-19 vaccine front-runners. Recent advancements in the field of RNA technology, vaccinology, and nanotechnology have generated interest in delivering safe and effective mRNA th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b0f88a1e945504ba8b4af825e8da083
https://doi.org/10.1016/j.addr.2020.12.014
https://doi.org/10.1016/j.addr.2020.12.014
Autor:
László Potor, József Balla, Katalin Éva Sikura, Ibolya Fürtös, Zoltán Hendrik, Zsolt Combi, Péter Gergely, György Balla, Matthew Whiteman, Gábor Méhes, Tamás Szerafin, Lívia Beke
Publikováno v:
Journal of Advanced Research
Journal of Advanced Research, Vol 27, Iss, Pp 165-176 (2021)
Journal of Advanced Research, Vol 27, Iss, Pp 165-176 (2021)
Graphical abstract
Highlights • H2S derived from CSE/CBS inhibits inflammation and calcification of valvular interstitial cells. • H2S releasing molecules inhibits inflammation and calcification of valvular interstitial cells. • H2S inhibi
Highlights • H2S derived from CSE/CBS inhibits inflammation and calcification of valvular interstitial cells. • H2S releasing molecules inhibits inflammation and calcification of valvular interstitial cells. • H2S inhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2577134f86e4d61d605b2cf8a2cb940a
http://europepmc.org/articles/PMC7728582
http://europepmc.org/articles/PMC7728582
Publikováno v:
Saudi Journal of Biological Sciences, Vol 27, Iss 2, Pp 736-750 (2020)
Saudi Journal of Biological Sciences
Saudi Journal of Biological Sciences
The incidence of Alzheimer’s disease (AD) has risen exponentially worldwide over the past decade. A growing body of research indicates that AD is linked to diabetes mellitus (DM) and suggests that impaired insulin signaling acts as a crucial risk f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82087843d8727a5c0d4d07ba5ff6b9bd
http://www.sciencedirect.com/science/article/pii/S1319562X19303286
http://www.sciencedirect.com/science/article/pii/S1319562X19303286
Autor:
Tilman Ziegler, Christian Kupatt
Publikováno v:
JACC: Basic to Translational Science
JACC: Basic to Translational Science, Vol 5, Iss 1, Pp 66-68 (2020)
JACC: Basic to Translational Science, Vol 5, Iss 1, Pp 66-68 (2020)
Visual Abstract
Highlights • DVDMS-SDT reduces neovascularization in late-stage atherosclerotic lesions in both rabbit and mouse models. • DVDMS-SDT enhances macrophage foam cell apoptosis, which in turn induces neovessel endothelial cell ap
Highlights • DVDMS-SDT reduces neovascularization in late-stage atherosclerotic lesions in both rabbit and mouse models. • DVDMS-SDT enhances macrophage foam cell apoptosis, which in turn induces neovessel endothelial cell ap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cecae0779c1370a051c7a6dafabf3421
https://doi.org/10.1016/j.jacbts.2019.12.003
https://doi.org/10.1016/j.jacbts.2019.12.003
Autor:
Anna Hultgårdh Nilsson, Pontus Dunér, Gunnar Engström, Christoph J. Binder, Jan Nilsson, Harry Björkbacka, Anki Knutsson
Publikováno v:
JACC: Basic to Translational Science
JACC: Basic to Translational Science, Vol 4, Iss 8, Pp 891-902 (2019)
JACC: Basic to Translational Science, Vol 4, Iss 8, Pp 891-902 (2019)
Visual Abstract
Highlights • There is strong experimental evidence that IL-5 has a protective role in atherosclerosis but the clinical importance of this remains poorly studied. • In a prospective study involving 696 subjects with a follow-u
Highlights • There is strong experimental evidence that IL-5 has a protective role in atherosclerosis but the clinical importance of this remains poorly studied. • In a prospective study involving 696 subjects with a follow-u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8591ebbf3d074225b9de87f67474343
http://europepmc.org/articles/PMC6939009
http://europepmc.org/articles/PMC6939009
Autor:
Yangyang Hu, Ting Yuan, Huan Chen, Ting Yang, Jing Wang, Hong Yu, Qing Yuan, Danli Fu, Xiang Xie, Wenfeng Xu
Publikováno v:
Redox Biology
Redox Biology, Vol 20, Iss, Pp 247-260 (2019)
Redox Biology, Vol 20, Iss, Pp 247-260 (2019)
Oxidative stress and inflammation interact in the development of diabetic atherosclerosis. Intracellular hyperglycemia promotes production of mitochondrial reactive oxygen species (ROS), increased formation of intracellular advanced glycation end-pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f9eba5d1c8ff637dfcb1b8003cebc6f
https://doi.org/10.1016/j.redox.2018.09.025
https://doi.org/10.1016/j.redox.2018.09.025
Autor:
Yusuke Ito, Yasuhiro Maejima, Shun Nakagama, Yuka Shiheido-Watanabe, Natsuko Tamura, Tetsuo Sasano
Publikováno v:
JACC: Basic to Translational Science
Visual Abstract
Highlights • An appropriate dose of RIV to inhibit the activity of factor Xa significantly suppressed the atherosclerotic area in the aorta of HFD-fed ApoE–/– mice. • Macrophage autophagy induced by 7KC administration was
Highlights • An appropriate dose of RIV to inhibit the activity of factor Xa significantly suppressed the atherosclerotic area in the aorta of HFD-fed ApoE–/– mice. • Macrophage autophagy induced by 7KC administration was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a0e5e26a6fa69436ef8f97344ae5b05
https://pubmed.ncbi.nlm.nih.gov/35024502
https://pubmed.ncbi.nlm.nih.gov/35024502
Autor:
Emily Igel, Patrick R. Wolfkiel, Anja Jaeschke, David Y. Hui, April Haller, Melissa A. Orr-Asman
Publikováno v:
The Journal of Biological Chemistry
Polymorphisms in the apolipoprotein E (apoE) gene are risk factors for chronic inflammatory diseases including atherosclerosis. The gene product apoE is synthesized in many cell types and has both lipid transport-dependent and lipid transport-indepen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3de00fa93eb2ea4fb3ca0f8d15d838ff
https://pubmed.ncbi.nlm.nih.gov/34425108
https://pubmed.ncbi.nlm.nih.gov/34425108