Zobrazeno 1 - 10
of 1 000
pro vyhledávání: '"antiviral effect"'
Autor:
Ivana Nemčovičová, Katarína Lopušná, Iveta Štibrániová, Fabio Benedetti, Federico Berti, Fulvia Felluga, Sara Drioli, Mattia Vidali, Jaroslav Katrlík, Lucia Pažitná, Alena Holazová, Jana Blahutová, Simona Lenhartová, Monika Sláviková, Boris Klempa, Miroslav Ondrejovič, Daniela Chmelová, Barbora Legerská, Stanislav Miertuš, Mária Klacsová, Daniela Uhríková, Lukáš Kerti, Vladimír Frecer
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 39, Iss 1 (2024)
AbstractThe viral genome of the SARS-CoV-2 coronavirus, the aetiologic agent of COVID-19, encodes structural, non-structural, and accessory proteins. Most of these components undergo rapid genetic variations, though to a lesser extent the essential v
Externí odkaz:
https://doaj.org/article/1ab0d8cfa120432f8905bf2f4c7f5d07
Autor:
Huai-rui Qin, Zhi Cao, Feng-zhe Lu, Wei Wang, Wenhui Zhao, Guimei Li, Hongliang Zhang, Shubai Wang, Zhihua Qin
Publikováno v:
BMC Veterinary Research, Vol 20, Iss 1, Pp 1-16 (2024)
Abstract Background Porcine epidemic diarrhea virus (PEDV) is a highly contagious coronavirus that causes severe diarrhea and death in neonatal piglets, which has brought huge economic losses to the pork industry worldwide since its first discovery i
Externí odkaz:
https://doaj.org/article/58e6343c46e94f3a890827cdb168025b
Autor:
Cai Dongjie, Shen Zifan, Tian Bin, Chen Jie, Zhang Yilin, Shen Liuhong, Wang Ya, Ma Xiaoping, Zuo Zhicai
Publikováno v:
Journal of Veterinary Research, Vol 68, Iss 1, Pp 35-44 (2024)
Bovine viral diarrhoea virus (BVDV) can cause diarrhoea (BVD) in an animal herd, leading to heavy economic losses. There are limited drugs available for treating and controlling BVD. This research aims to investigate the antiviral and immunoregulator
Externí odkaz:
https://doaj.org/article/4198ae3427e146b181f1ff6e566fe1e9
Autor:
V. V. Zarubaev, A. V. Garshinina, Ya. L. Esaulkova, M. G. Mihalskij, V. S. Smirnov, T. A. Kudryavtseva, S. V. Petlenko, V. A. Zaplutanov
Publikováno v:
Антибиотики и Химиотерапия, Vol 68, Iss 9-10, Pp 46-57 (2024)
Introduction. Due to the ability of the influenza virus to mutate, it is necessary to constantly search for new drugs with preventive and direct antiviral effects.The aim of the study is to investigate the protective antiviral properties of the drug
Externí odkaz:
https://doaj.org/article/60db99eb251f4c8b8799e1291ec718c2
Autor:
Liyun Song, Daoshun Zhang, Tianbo Liu, Changqing Jiang, Bin Li, Changquan Li, Lili Shen, Ying Li, Fenglong Wang, Yubing Jiao, Jinguang Yang
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Background Viral diseases continue to pose a major threat to the world’s commercial crops. The in-depth exploration and efficient utilization of resistance proteins have become crucial strategies for their control. However, current deliver
Externí odkaz:
https://doaj.org/article/af46034ace534cfa97f2b450cc5035ab
Publikováno v:
Сахарный диабет, Vol 26, Iss 6, Pp 585-595 (2023)
Metformin, known in the medical community as the drug of first choice for type 2 diabetes mellitus, belongs to the group of biguanides and has proven to be an effective treatment in clinical practice. Our knowledge of the pharmacodynamic properties o
Externí odkaz:
https://doaj.org/article/22e635b6c2d9481bb298ea809e279f27
Publikováno v:
Life, Vol 14, Iss 9, p 1050 (2024)
The effectiveness of acyclovir, a selective anti-herpesvirus agent, was tested both in silico and in vitro against two ranaviruses, namely the European catfish virus (ECV) and Frog virus 3 (FV3). ECV can cause significant losses in catfish aquacultur
Externí odkaz:
https://doaj.org/article/26d3a3c4411e4ad3b70a26b9173cfa04
Autor:
V. V. Zarubaev, V. S. Smirnov, T. A. Kudryavtseva, S. V. Petlenko, A. V. Slita, H. Minh, V. A. Zaplutanov
Publikováno v:
Антибиотики и Химиотерапия, Vol 68, Iss 3-4, Pp 4-10 (2023)
Introduction. The requirements of modern clinical guidelines for the treatment of respiratory viral infections suggest the possibility of identifying a specific viral pathogen. In this regard, the search for drugs with selective activity against resp
Externí odkaz:
https://doaj.org/article/a411a9f7c409416da06d4e22312518d1
Publikováno v:
Фармакоэкономика, Vol 16, Iss 1, Pp 105-124 (2023)
Background. The rapidly developing resistance of viruses to synthetic antiviral drugs indicates the need to use substances with multitarget action (to avoid polypharmacy and to improve the safety of treatment).Objective: systematic analysis of the sc
Externí odkaz:
https://doaj.org/article/6f1405b3114e46ebabad2fbcc24f9535
Publikováno v:
International Journal of Nanomedicine, Vol Volume 18, Pp 1561-1575 (2023)
Woo-Jin Jeon,1,* Hong-Ki Lee,2,3,* Young-Guk Na,1 Minwoo Jung,1 Su-Cheol Han,2 Jeong Ho Hwang,2 Eunhye Jung,4 Dasom Hwang,4 Jin Soo Shin,4 Cheong-Weon Cho1 1College of Pharmacy and Institute of Drug Research and Development, Chungnam National
Externí odkaz:
https://doaj.org/article/7529b685e3894c90b8dcae3d24ad2bec