Zobrazeno 1 - 10
of 784
pro vyhledávání: '"antiparasitic activity"'
Autor:
Nancy E. Rodríguez-Garza, Ramiro Quintanilla-Licea, Ricardo Gomez-Flores, Lucio Galaviz-Silva, Zinnia J. Molina-Garza
Publikováno v:
Plants, Vol 13, Iss 16, p 2177 (2024)
Chagas disease, caused by the protozoan Trypanosoma cruzi, represents an important and worldwide public health issue, particularly in Latin America. Limitations of conventional treatment with benznidazole and nifurtimox underscore the urgent need for
Externí odkaz:
https://doaj.org/article/66f4e462afac45a9a7790dabe83a4a7f
Autor:
Jozef Stec, William H. Witola
Publikováno v:
Results in Chemistry, Vol 6, Iss , Pp 101212- (2023)
The Knoevenagel condensation (KC) is an important reaction known in organic chemistry for over a century. The catalytic version of this transformation, often with the use of piperidine as the catalyst, gained more attention in recent decades. However
Externí odkaz:
https://doaj.org/article/a6ff7445de4545bb9cf85f28354f39e3
Autor:
Murat Bozdag, Freke Mertens, An Matheeussen, Natascha Van Pelt, Kenn Foubert, Nina Hermans, Guido R. Y. De Meyer, Koen Augustyns, Wim Martinet, Guy Caljon, Pieter Van der Veken
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 9, p 4693 (2024)
Herein, we report a series of 1,3-diarylpyrazoles that are analogues of compound 26/HIT 8. We previously identified this molecule as a ‘hit’ during a high-throughput screening campaign for autophagy inducers. A variety of synthetic strategies wer
Externí odkaz:
https://doaj.org/article/18dabefed2da4cbd90ffbaf508400672
Autor:
Kourosh Cheraghipour, Amal Khudair Khalaf, Kobra Moradpour, Masoomeh Zivdari, Marjan Beiranvand, Pegah Shakib, Hossein Mahmoudvand, Abdolrazagh Marzban
Publikováno v:
Heliyon, Vol 9, Iss 8, Pp e19295- (2023)
Background: In this study, zinc oxide nanoparticles-coated with eugenol (ZnO@Eug) were synthesized and evaluated as a nanosuspension (NSus) formulation against Toxoplasma gondii in vitro and in vivo. Methods: An anti-Toxoplasma activity assay for ZnO
Externí odkaz:
https://doaj.org/article/0d93010ebbd04c9b8618a61d24e9038c
Publikováno v:
Marine Drugs, Vol 21, Iss 12, p 609 (2023)
Parasitic diseases still compromise human health. Some of the currently available therapeutic drugs have limitations considering their adverse effects, questionable efficacy, and long treatment, which have encouraged drug resistance. There is an urge
Externí odkaz:
https://doaj.org/article/f36ed6e6594b48b49489f902f7a0a8af
Akademický článek
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Akademický článek
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Akademický článek
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Autor:
Álvaro Martín-Montes, Sandra Jimenez-Falcao, Santiago Gómez-Ruiz, Clotilde Marín, José M. Mendez-Arriaga
Publikováno v:
Pharmaceuticals, Vol 16, Iss 10, p 1380 (2023)
Leishmaniasis and Chagas disease are still considered neglected illnesses due to the lack of investment in research, despite the fact that almost one million new cases are reported every year. Four 7-oxo-5-phenyl-1,2,4-triazolo[1,5-a]pyrimidine (Hftp
Externí odkaz:
https://doaj.org/article/0258517298684f64ac01cc21f132e3d5
Autor:
Luis M. Bautista-Sopelana, Paula Bolívar, María Teresa Gómez-Muñoz, Rafael A. Martínez-Díaz, María Fe Andrés, Juan Carlos Alonso, Carolina Bravo, Azucena González-Coloma
Publikováno v:
Frontiers in Ecology and Evolution, Vol 10 (2022)
Plants are not only used as energy and nutrient resources for herbivores. Plants can be ingested because of their activity against host parasites and other pathogens. This so-called medicinal role of plants is well reported in ethnopharmacology and u
Externí odkaz:
https://doaj.org/article/5d05464f3d2f4156893019b1df378f43