Zobrazeno 1 - 10
of 644
pro vyhledávání: '"antimalarial drug resistance"'
Autor:
Ameyo Monique Dorkenoo, Marian Warsame, Essoham Ataba, Manani Hemou, Kossi Yakpa, Efoe Sossou, M’badi Mitigmsagou, Carmel Diwaba Teou, Emmanuelle Caspar, Laurence Ma, Koffi Edem Djadou, Tinah Atcha-Oubou, Charlotte Rasmussen, Didier Menard
Publikováno v:
Malaria Journal, Vol 23, Iss 1, Pp 1-17 (2024)
Abstract Background Artemether-lumefantrine (AL) and dihydroartemisinin-piperaquine (DP) are the currently recommended first- and second-line therapies for uncomplicated Plasmodium falciparum infections in Togo. This study assessed the efficacy of th
Externí odkaz:
https://doaj.org/article/84a2192568d44c24b6bbd91ca6b741bc
Autor:
Giulia Manzoni, Rady Try, Jean Olivier Guintran, Céline Christiansen-Jucht, Elodie Jacoby, Siv Sovannaroth, Zaixing Zhang, Vilasack Banouvong, Matthew Scott Shortus, Rita Reyburn, Chitsavang Chanthavisouk, Nay Yi Yi Linn, Badri Thapa, San Kyawt Khine, Prayuth Sudathip, Deyer Gopinath, Nguyen Quang Thieu, Mya Sapal Ngon, Dai Tran Cong, Liu Hui, James Kelley, Neena Nee Kesar Valecha, Maria Dorina Bustos, Charlotte Rasmussen, Luciano Tuseo
Publikováno v:
Malaria Journal, Vol 23, Iss 1, Pp 1-16 (2024)
Abstract Malaria remains a global health challenge, disproportionately affecting vulnerable communities. Despite substantial progress, the emergence of anti-malarial drug resistance poses a constant threat. The Greater Mekong Subregion (GMS), which i
Externí odkaz:
https://doaj.org/article/69f2cbee7a094991beb39bfe316e0dd6
Autor:
Nadine Kalenda Kayiba, Evariste Tshibangu-Kabamba, Angel Rosas-Aguirre, Natsuko Kaku, Yu Nakagama, Akira Kaneko, Dieudonné Mvumbi Makaba, Doudou Yobi Malekita, Brecht Devleesschauwer, Joris Losimba Likwela, Pius Kabututu Zakayi, Patrick DeMol, Georges Mvumbi Lelo, Marie-Pierre Hayette, Paul Lusamba Dikassa, Yasutoshi Kido, Niko Speybroeck
Publikováno v:
Tropical Medicine and Health, Vol 51, Iss 1, Pp 1-16 (2023)
Abstract Context The Democratic Republic of Congo (DRC), one of the most malaria-affected countries worldwide, is a potential hub for global drug-resistant malaria. This study aimed at summarizing and mapping surveys of malaria parasites carrying mol
Externí odkaz:
https://doaj.org/article/b21abea4264c4fdfb8ee8f3f224dcddc
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Ferroptosis is an iron-dependent form of regulated cell death characterized by glutathione (GSH) depletion, glutathione peroxidase 4 (GPX4) inactivation, and the build-up of lipotoxic reactive species. Ferroptosis-targeted induction is a promising th
Externí odkaz:
https://doaj.org/article/cc4b12ace9d64ec98b0d177b142ca824
Autor:
David O Oladejo, Dorathy O Anzaku, Collins O Mamudu, Temitope Elugbadebo, Titilope M Dokunmu, Ezekiel F Adebiyi, Emeka EJ Iweala
Publikováno v:
Scientific African, Vol 23, Iss , Pp e02010- (2024)
Resistance to antimalarial drugs leads a global recurrence of malaria, posing a significant challenge to malaria control. This study aimed to assess gene expression and resistance profiles in clinical isolates, and validate the inhibitory effect of M
Externí odkaz:
https://doaj.org/article/64d4ba2e8afa4d75a1d3af7964311e94
Autor:
Sena Adzoa Matrevi, Tryphena Adams, Kwesi Zandoh Tandoh, Philip Opoku-Agyeman, Selassie Bruku, Nana Aba Ennuson, Paa Kwesi Apau-Danso, Emmanuel Fiagbedzi, Mary Avornyo, Charles James Myers, Joy Futagbi, Oheneba Charles Hagan, Benjamin Abuaku, Kwadwo Ansah Koram, Gordon Awandare, Neils Ben Quashie, Nancy Odurowah Duah-Quashie
Publikováno v:
Frontiers in Epidemiology, Vol 4 (2024)
IntroductionAntimalarial drugs including artemisinin-based combination therapy (ACT) regimens and sulphadoxine-pyrimethamine (SP) are used in Ghana for malaria therapeutics and prophylaxis respectively. The genetic basis of Plasmodium falciparum deve
Externí odkaz:
https://doaj.org/article/8ffd5be5604c43d4aa8e052ece5cadee
Autor:
Erin Coonahan, Hunter Gage, Daisy Chen, Emilia Virginia Noormahomed, Titos Paulo Buene, Irina Mendes de Sousa, Kevan Akrami, Lucia Chambal, Robert T. Schooley, Elizabeth A. Winzeler, Annie N. Cowell
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
ABSTRACT The emergence of Plasmodium falciparum drug resistance threatens the efficacy of antimalarial therapies globally. Population genomic studies have been instrumental in mapping malaria genes associated with drug resistance. However, to underst
Externí odkaz:
https://doaj.org/article/4eac6d358c37444e9056cb91eb3ee104
Publikováno v:
Malaria Journal, Vol 21, Iss 1, Pp 1-9 (2022)
Abstract Background Artemisinin-based combination therapy (ACT) has been recommended as the first-line treatment by the World Health Organization to treat uncomplicated Plasmodium falciparum malaria. However, the emergence and spread of P. falciparum
Externí odkaz:
https://doaj.org/article/72707eded26949a78162df133dbbbb76
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