Rapid generation of human recombinant monoclonal antibodies from antibody-secreting cells using ferrofluid-based technology

Autor: Veronica Strazza, Marco Rossi, Andrea Avati, Giusy Tiseo, Marco Falcone, Maria Grazia Cusi, Francesco Menichetti, Paola Ricciardi-Castagnoli, Cristina Tinti, Piero Pileri

Publikováno v: Frontiers in Immunology, Vol 15 (2024)

Monoclonal antibodies (mAbs) are one of the most important classes of biologics with high therapeutic and diagnostic value, but traditional methods for mAbs generation, such as hybridoma screening and phage display, have limitations, including low ef

Externí odkaz: https://doaj.org/article/98d920131c7142098058ef4d1793238d

High-throughput single-cell screening of viable hybridomas and patient-derived antibody-secreting cells using punchable microwells.

Autor: Rubben, Kaat¹ (AUTHOR), Vander Plaetsen, Ann-Sophie¹ (AUTHOR), Almey, Ruben¹ (AUTHOR), Tytgat, Olivier¹ (AUTHOR), Deserranno, Koen¹ (AUTHOR), Debaere, Jamie² (AUTHOR), Acar, Delphine Diana³ (AUTHOR), Meuleman, Philip⁴ (AUTHOR), Deforce, Dieter¹ (AUTHOR), Van Nieuwerburgh, Filip¹ (AUTHOR) filip.vannieuwerburgh@ugent.be

Publikováno v: Artificial Cells, Nanomedicine & Biotechnology. Dec2024, Vol. 52 Issue 1, p426-436. 11p.

Author Correction: Immune response and protective efficacy of the SARS-CoV-2 recombinant spike protein vaccine S-268019-b in mice.

Autor: Homma, Tomoyuki¹ (AUTHOR), Nagata, Noriyo² (AUTHOR), Hashimoto, Masayuki¹ (AUTHOR), Iwata-Yoshikawa, Naoko² (AUTHOR), Seki, Naomi M.¹ (AUTHOR), Shiwa-Sudo, Nozomi² (AUTHOR), Ainai, Akira³ (AUTHOR), Dohi, Keiji¹ (AUTHOR), Nikaido, Eiji⁴ (AUTHOR), Mukai, Akiko⁵ (AUTHOR), Ukai, Yuuta¹ (AUTHOR), Nakagawa, Takayuki¹ (AUTHOR), Shimo, Yusuke⁶ (AUTHOR), Maeda, Hiroki¹ (AUTHOR), Shirai, Seiki¹ (AUTHOR), Aoki, Miwa¹ (AUTHOR), Sonoyama, Takuhiro⁷ (AUTHOR), Sato, Mamoru⁵ (AUTHOR), Fumoto, Masataka⁴ (AUTHOR), Nagira, Morio¹ (AUTHOR)

Publikováno v: Scientific Reports. 1/31/2024, Vol. 14 Issue 1, p1-3. 3p.

A rhesus macaque intragastric challenge model for evaluating the safety, immunogenicity, and efficacy of live-attenuated Shigella dysenteriae 1 vaccine candidates.

Autor: Ruamsap, Nattaya, Imerbsin, Rawiwan, Khanijou, Patchariya, Gonwong, Siriphan, Oransathit, Wilawan, Barnoy, Shoshana, Venkatesan, Malabi M., Chaudhury, Sidhartha, Islam, Dilara

Publikováno v: Frontiers in Microbiology; 2024, p1-13, 13p

Anti-dsDNA B-Cell ELISpot as a Monitoring and Flare Prediction Tool in SLE Patients.

Autor: Pérez-Isidro, Albert^1,2 (AUTHOR), Xipell, Marc^2,3,4 (AUTHOR), Llobell, Arturo^1,2 (AUTHOR), De Moner, Noemí¹ (AUTHOR), Lledó, Gema M.^2,5,6 (AUTHOR), Cervera, Ricard^2,5,6 (AUTHOR), Prieto-González, Sergio^2,5,6 (AUTHOR), Quintana, Luis F.^2,3,4 (AUTHOR), Espinosa, Gerard^2,5,6 (AUTHOR), García-Ormaechea, Mila^1,7 (AUTHOR), Ruiz-Ortiz, Estíbaliz^1,2 (AUTHOR) esruiz@clinic.cat, Viñas, Odette^1,2 (AUTHOR) esruiz@clinic.cat

Publikováno v: Journal of Clinical Medicine. Feb2023, Vol. 12 Issue 4, p1295. 15p.