Zobrazeno 1 - 10
of 320
pro vyhledávání: '"antigen-binding site"'
Autor:
Laura E. Ruff, Jessica A. Pfeilsticker, Nicholas E. Johnsen, Sarah Nocchi, Bradley T. Messmer
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-8 (2018)
Abstract Mimotope peptides selected from combinatorial peptide libraries can be used as capture reagents for immunoassay detection of therapeutic monoclonal antibodies (mAbs). We report the use of phage display libraries to identify peptide ligands (
Externí odkaz:
https://doaj.org/article/dbcb2a18d1b547218b99e669ed8adfff
Autor:
Eric Chun Yiu Law, Danny Tze Ming Leung, Frankie Chi Hang Tam, Kitty Kit Ting Cheung, Naomi Hua Yin Cheng, Pak Leong Lim
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Antibodies are well-known protein mediators of immunity. IgM is the primordial member and the neglected sibling of the later-evolved and more proficient IgG in regard to their therapeutic and diagnostic use. Serendipitously, however, we found a parad
Externí odkaz:
https://doaj.org/article/12e4da23223a4cdfb4efefda72c38548
Akademický článek
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Publikováno v:
Veterinární Medicína, Vol 57, Iss 9, Pp 439-513 (2012)
Single-domain antibody (sdAb) fragments derived from heavy-chain antibodies of camelids and cartilaginous fish represent a new generation of therapeutic agents and immunoreagents. Due to their unique characteristics, such as low molecular weight, hig
Externí odkaz:
https://doaj.org/article/bf297ea3abf44422b7982bebfbc07478
Autor:
Herrin, Brantley R., Alder, Matthew N., Roux, Kenneth H., Sina, Christina, Ehrhardt, Götz R. A., Boydston, Jeremy A., Turnbough,, Charles L., Cooper, Max D.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2008 Feb 01. 105(6), 2040-2045.
Externí odkaz:
https://www.jstor.org/stable/25451410
Autor:
Lin, Lien-Ching, Putnam, Frank W.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 1978 Jun 01. 75(6), 2649-2653.
Externí odkaz:
https://www.jstor.org/stable/68299
Autor:
Juan C eAlmagro
Publikováno v:
Frontiers in Immunology, Vol 3 (2012)
Antibodies are the fastest-growing segment of the biologics market. The success of antibody-based drugs resides in their exquisite specificity, high potency, stability, solubility, safety and relatively inexpensive manufacturing process in comparison
Externí odkaz:
https://doaj.org/article/7cd9fe7c3cce404f90eb711ae18fe898
Autor:
Doreen Könning, Martin Empting, Julius Grzeschik, Steffen C. Hinz, Stefan Zielonka, Harald Kolmar, Simon Krah
Publikováno v:
BIOspektrum. 24:142-145
The adaptive immune system of sharks comprises a very interesting antibody isotype named immunoglobulin new antigen receptor (IgNAR). In contrast to classical antibodies, the antigen binding site of the heavy chain only immunoglobulin is formed by a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::095e64103ac295ffe97fbed351b48bac
https://doi.org/10.1007/s12268-018-0902-0
https://doi.org/10.1007/s12268-018-0902-0
Publikováno v:
Protein Expression and Purification. 175:105711
Asymmetric IgG-like bispecific antibodies (bsAbs) are normally derived from two parental mAbs with different origin. Despite the implementation of heterodimerization-promoting strategy in the design, homodimerization can still occur at a low level du
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c2d4b732a01272b84d558855f3e98ee
https://doi.org/10.1016/j.pep.2020.105711
https://doi.org/10.1016/j.pep.2020.105711
Autor:
Bradley Todd Messmer, Sarah Nocchi, Laura E. Ruff, Jessica A. Pfeilsticker, Nicholas E. Johnsen
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-8 (2018)
Mimotope peptides selected from combinatorial peptide libraries can be used as capture reagents for immunoassay detection of therapeutic monoclonal antibodies (mAbs). We report the use of phage display libraries to identify peptide ligands (Veritopes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acbb8df4fd2ca9b428aa4c8057252aae
https://pubmed.ncbi.nlm.nih.gov/30262856
https://pubmed.ncbi.nlm.nih.gov/30262856