Zobrazeno 1 - 10
of 1 793
pro vyhledávání: '"antigen delivery"'
Publikováno v:
Asian Pacific Journal of Tropical Biomedicine, Vol 14, Iss 8, Pp 359-368 (2024)
Objective: To prepare and characterize polycaprolactone (PCL) nanoparticles loaded with sonicator fragmented (SLA) and freeze- thaw Leishmania antigens (FTLA) and to investigate the in vitro immunogenicity of antigen-encapsulated nanoparticles with c
Externí odkaz:
https://doaj.org/article/df39408a42744c9da1ceb2643a4feac2
Autor:
Tiziana Schioppa, Carolina Gaudenzi, Giovanni Zucchi, Arianna Piserà, Yasmin Vahidi, Laura Tiberio, Silvano Sozzani, Annalisa Del Prete, Daniela Bosisio, Valentina Salvi
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Extracellular vesicles (EVs) are nanosized heat-stable vesicles released by virtually all cells in the body, including tumor cells and tumor-infiltrating dendritic cells (DCs). By carrying molecules from originating cells, EVs work as cell-t
Externí odkaz:
https://doaj.org/article/3162b48a36134273ad13e520ba3014b5
Autor:
Caiqian Wang, Yuanyuan Geng, Haoran Wang, Zeheng Ren, Qingxiu Hou, An Fang, Qiong Wu, Liqin Wu, Xiujuan Shi, Ming Zhou, Zhen F Fu, Jonathan F Lovell, Honglin Jin, Ling Zhao
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 6, Pp 1451-1483 (2024)
Abstract Although protein subunit vaccines generally have acceptable safety profiles with precise antigenic content, limited immunogenicity can lead to unsatisfactory humoral and cellular immunity and the need for vaccine adjuvants and delivery syste
Externí odkaz:
https://doaj.org/article/a34d3dfc3d324d818a21353b94f3adc5
Autor:
Qin Wang, Rui Peng, Haoyue Qi, Ruihan Xu, Wanmin Liu, Fanyan Meng, Shiyao Du, Lixia Yu, Jia Wei, Fangcen Liu, Rutian Li
Publikováno v:
MedComm, Vol 5, Iss 7, Pp n/a-n/a (2024)
Abstract T‐cell receptor (TCR) engineered T‐cell therapy, unlike chimeric antigen receptor T‐cell therapy, relies on the inherent ability of TCRs to detect a wider variety of antigenic epitopes, such as protein fragments found internally or ext
Externí odkaz:
https://doaj.org/article/a87cb30843a549eca7c9103df556b558
Autor:
Rui Tada, Yuzuho Nagai, Miki Ogasawara, Momoko Saito, Akihiro Ohshima, Daisuke Yamanaka, Jun Kunisawa, Yoshiyuki Adachi, Yoichi Negishi
Publikováno v:
Vaccines, Vol 12, Iss 5, p 449 (2024)
The development of mucosal vaccines, which can generate antigen-specific immune responses in both the systemic and mucosal compartments, has been recognized as an effective strategy for combating infectious diseases caused by pathogenic microbes. Our
Externí odkaz:
https://doaj.org/article/f22c00306b1e4fd9a851447ee90392fc
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Bacterium-like particles (BLPs) are hollow peptidoglycan particles obtained from food-grade Lactococcus lactis inactivated by hot acid. With the advantage of easy preparation, high safety, great stability, high loading capacity, and high mucosal deli
Externí odkaz:
https://doaj.org/article/9d0043ba16f94c9e9cf7975cf2160267
Autor:
Vishnu Raman, Lars M. Howell, Shoshana M. K. Bloom, Christopher L. Hall, Victoria E. Wetherby, Lisa M. Minter, Ashish A. Kulkarni, Neil S. Forbes
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionImmunotherapies have shown great promise, but are not effective for all tumors types and are effective in less than 3% of patients with pancreatic ductal adenocarcinomas (PDAC). To make an immune treatment that is effective for more cance
Externí odkaz:
https://doaj.org/article/944ab464cdd44703a74bbcb1fec0ab5b
Autor:
Martin Beukema, Shuran Gong, Kasem Al-Jaawni, Jacqueline J. de Vries-Idema, Florian Krammer, Fan Zhou, Rebecca Jane Cox, Anke Huckriede
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionInfluenza vaccines play a vital role in protecting individuals from influenza virus infection and severe illness. However, current influenza vaccines have suboptimal efficacy, which is further reduced in cases where the vaccine strains do
Externí odkaz:
https://doaj.org/article/391dab5549cd48148cde167a0e60d711
Autor:
Jinsong Zhang, Jianghua Yang, Qianlin Li, Ruihao Peng, Shoudong Fan, Huaimin Yi, Yuying Lu, Yuanli Peng, Haozhen Yan, Lidan Sun, Jiahai Lu, Zeliang Chen
Publikováno v:
Advanced Science, Vol 10, Iss 26, Pp n/a-n/a (2023)
Abstract Antigen delivery based on non‐virus‐like particle self‐associating protein nanoscffolds, such as Aquifex aeolicus lumazine synthase (AaLS), is limited due to the immunotoxicity and/or premature clearance of antigen‐scaffold complex r
Externí odkaz:
https://doaj.org/article/09b1a2b7f17d4b049923de434e79e28d
Autor:
Ruifeng Mao, Menglan Yang, Rui Yang, Yingying Chen, Enjie Diao, Tong Zhang, Dengchao Li, Xin Chang, Zhenjing Chi, Yefu Wang
Publikováno v:
Drug Delivery, Vol 29, Iss 1, Pp 925-936 (2022)
Antigen-specific immune tolerance, which possesses great potential in preventing or curing type 1 diabetes mellitus (T1DM), can be induced by oral vaccination with T1DM-related autoantigens. However, direct administration of autoantigens via oral rou
Externí odkaz:
https://doaj.org/article/692454666a994d669fa053ccf05b97a3