Zobrazeno 1 - 10
of 7 386
pro vyhledávání: '"antiestrogen"'
Autor:
Zsuzsanna Suba
Publikováno v:
Current Oncology, Vol 31, Iss 9, Pp 4885-4907 (2024)
Background: Breast cancer incidence and mortality exhibit a rising trend globally among both premenopausal and postmenopausal women, suggesting that there are serious errors in our preventive and therapeutic measures. Purpose: Providing a series of v
Externí odkaz:
https://doaj.org/article/aefb93d036eb45d288f1bb72925b94a9
Autor:
Andrea K. Corbet, Emmanuel Bikorimana, Raya I. Boyd, Doha Shokry, Kelly Kries, Ayush Gupta, Anneliese Paton, Zhengyang Sun, Zeeshan Fazal, Sarah J. Freemantle, Erik R. Nelson, Michael J. Spinella, Ratnakar Singh
Publikováno v:
Translational Oncology, Vol 33, Iss , Pp 101676- (2023)
G0/G1 switch gene 2 (G0S2) is known to inhibit lipolysis by inhibiting adipose triglyceride lipase (ATGL). In this report, we dissect the role of G0S2 in ER+ versus ER- breast cancer. Overexpression of G0S2 in ER- cells increased cell proliferation,
Externí odkaz:
https://doaj.org/article/cbcbc9b7c9dc4ba880141b3cdbbac673
A Novel Metastatic Estrogen Receptor-Expressing Breast Cancer Model with Antiestrogen Responsiveness
Autor:
Kendall L. Langsten, Lihong Shi, Adam S. Wilson, Salvatore Lumia, Brian Westwood, Alexandra M. Skeen, Maria T. Xie, Victoria E. Surratt, JoLyn Turner, Carl D. Langefeld, Ravi Singh, Katherine L. Cook, Bethany A. Kerr
Publikováno v:
Cancers, Vol 15, Iss 24, p 5773 (2023)
Most women diagnosed with breast cancer (BC) have estrogen receptor alpha-positive (ER+) disease. The current mouse models of ER+ BC often rely on exogenous estrogen to encourage metastasis, which modifies the immune system and the function of some t
Externí odkaz:
https://doaj.org/article/b291edeb12354304b469e1ad7e915ebf
Akademický článek
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Publikováno v:
Middle East Fertility Society Journal, Vol 27, Iss 1, Pp 1-17 (2022)
Abstract Background Embryo implantation is a tightly regulated sequence of events regulated by ovarian steroids, estrogen and progesterone, and their downstream targets. Ovarian steroids regulate most of the genes involved in embryo implantation and
Externí odkaz:
https://doaj.org/article/2556fcec9938487084941586e6b8fcba
Publikováno v:
Current Oncology, Vol 28, Iss 3, Pp 1803-1822 (2021)
Background: Hormone receptor-positive and HER2-negative breast cancer (HR + BC) is the most prevalent breast cancer. Endocrine therapy is the mainstay of treatment, however, due to the heterogeneous nature of the disease, resistance to endocrine ther
Externí odkaz:
https://doaj.org/article/35705a7ccf71476badce99850ff78ed7
Autor:
David J Hosfield, Sandra Weber, Nan-Sheng Li, Madline Sauvage, Carstyn F Joiner, Govinda R Hancock, Emily A Sullivan, Estelle Ndukwe, Ross Han, Sydney Cush, Muriel Lainé, Sylvie C Mader, Geoffrey L Greene, Sean W Fanning
Publikováno v:
eLife, Vol 11 (2022)
Chemical manipulation of estrogen receptor alpha ligand binding domain structural mobility tunes receptor lifetime and influences breast cancer therapeutic activities. Selective estrogen receptor modulators (SERMs) extend estrogen receptor alpha (ER
Externí odkaz:
https://doaj.org/article/a9802c2206974ca0b24d086125724f5f
Publikováno v:
Tzu-Chi Medical Journal, Vol 32, Iss 2, Pp 175-180 (2020)
Objective: Previous Western studies reported that older (≥50 years) breast cancer survivors with tamoxifen treatment had higher risk of endometrial cancer. This study aims to disclose whether younger (
Externí odkaz:
https://doaj.org/article/b31de04a36a347dca122b245d1c0bbc7
Autor:
Christina W. Yde
Publikováno v:
Molecular & Cellular Oncology, Vol 8, Iss 6 (2021)
Antiestrogen resistance is a major clinical limitation in treatment of breast cancer. We have recently reported that Aurora A and Mcl-1 (myeloid cell leukemia 1) are potential novel treatment targets in antiestrogen-resistant breast cancer cells and
Externí odkaz:
https://doaj.org/article/e8017d8bc210445faf1c18ae16f950d4
Akademický článek
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