Zobrazeno 1 - 10
of 175
pro vyhledávání: '"antiepileptogenesis"'
Autor:
Chenxu Li, Pablo M. Casillas‐Espinosa, Patricia Grandizoli Saletti, Tina Chi, Glenn Yamakawa, Juliana Silva, Matt Hudson, Wei Liu, Nigel C. Jones, Sandy R. Shultz, Idrish Ali, Usha Mishra, James C. Cloyd, Solomon L. Moshe ́, Aristea S. Galanopoulou, Terence J. O'Brien, Lisa D. Coles
Publikováno v:
Pharmacology Research & Perspectives, Vol 12, Iss 6, Pp n/a-n/a (2024)
Abstract Post‐traumatic epilepsy (PTE) is a life‐long complication of traumatic brain injury (TBI). The development of PTE is associated with neurological morbidity and increases the risk of mortality. An aim of EpiBioS4Rx (Epilepsy Bioinformatic
Externí odkaz:
https://doaj.org/article/37bb36c25b624ffb8db3ae01b54fe547
Akademický článek
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Autor:
Jacqueline A. French, Martina Bebin, Marc A. Dichter, Jerome Engel Jr., Adam L. Hartman, Sergiusz Jóźwiak, Pavel Klein, James McNamara Sr., Roy Twyman, Paul Vespa
Publikováno v:
Epilepsia Open, Vol 6, Iss 3, Pp 483-492 (2021)
Abstract This is a summary report of clinical and regulatory issues discussed at the 2018 NINDS workshop, entitled “Accelerating Therapies for Antiepileptogenesis and Disease Modification.” The intent of the workshop was to optimize and accelerat
Externí odkaz:
https://doaj.org/article/531730396fe34253a66a9b0c974ba20d
Autor:
Jerome Engel, Jr
Publikováno v:
Neurobiology of Disease, Vol 123, Iss , Pp 3-7 (2019)
Epilepsy is one of the most common brain disorders, causing serious disability and premature death worldwide. Approximately 1.2% of the U.S. population has active epilepsy, and 30 to 40% have seizures that do not respond to antiseizure drugs. There c
Externí odkaz:
https://doaj.org/article/392ac3660a734f80997c2310bdfc18ad
Publikováno v:
Neurobiology of Disease, Vol 123, Iss , Pp 42-58 (2019)
A biomarker is a characteristic that is measured as an indicator of normal biologic processes, pathogenic processes, or responses to an exposure or intervention, including therapeutic interventions. Biomarker modalities include molecular, histologic,
Externí odkaz:
https://doaj.org/article/799f11f55bff4bdd8dfc4a23d098fd96
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Asla Pitkänen, Noora Huusko, Xavier Ekolle Ndode-Ekane, Jenni Kyyriäinen, Anssi Lipponen, Anu Lipsanen, Alejandra Sierra, Tamuna Bolkvadze
Publikováno v:
Neurobiology of Disease, Vol 72, Iss , Pp 224-232 (2014)
Disease modification of epilepsy refers to the alleviation of epileptogenesis or comorbidities after genetic or acquired epileptogenic brain insults. There are currently 30 proof-of-concept experimental pharmacologic studies that have demonstrated so
Externí odkaz:
https://doaj.org/article/8f4ecbfa7d1043cf95c4ee94b3bed39a
Autor:
Yun Hwang, Shilpa D. Kadam
Publikováno v:
Epilepsy Currents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa93f3ebfbf4c259e842c1e3521f33be
https://doi.org/10.1177/15357597211030384
https://doi.org/10.1177/15357597211030384
Autor:
Twyman Roy E, Jerome Engel, Pavel Klein, Marc A. Dichter, Sergiusz Jóźwiak, James O. McNamara, Adam L. Hartman, Martina Bebin, Jacqueline A. French, Paul M. Vespa
Publikováno v:
Epilepsia Open
Epilepsia Open, Vol 6, Iss 3, Pp 483-492 (2021)
Epilepsia Open, Vol 6, Iss 3, Pp 483-492 (2021)
This is a summary report of clinical and regulatory issues discussed at the 2018 NINDS workshop, entitled “Accelerating Therapies for Antiepileptogenesis and Disease Modification.” The intent of the workshop was to optimize and accelerate develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18b1c25037a6d5acafbf72dd9df27dfd
http://europepmc.org/articles/PMC8408600
http://europepmc.org/articles/PMC8408600
Autor:
Gilles van Luijtelaar, Asht M. Mishra, Peter Edelbroek, Daniel Coman, Nikita Frankenmolen, Pauline Schaapsmeerders, Giulio Covolato, Nathan Danielson, Hannah Niermann, Kryzstof Janeczko, Anne Kiemeneij, Julija Burinov, Chhitij Bashyal, Madeline Coquillette, Annika Lüttjohann, Fahmeed Hyder, Hal Blumenfeld, Clementina M. van Rijn
Publikováno v:
Neurobiology of Disease, Vol 60, Iss , Pp 126-138 (2013)
The beneficial effects of chronic and early pharmacological treatment with ethosuximide on epileptogenesis were studied in a genetic absence epilepsy model comorbid for depression. It was also investigated whether there is a critical treatment period
Externí odkaz:
https://doaj.org/article/4578cdd33f1e4920bf374d245fe64fa8