Expression Analysis of Outer Membrane Protein HPS_06257 in Different Strains of Glaesserella parasuis and Its Potential Role in Protective Immune Response against HPS_06257-Expressing Strains via Antibody-Dependent Phagocytosis

Autor: Xiaojun Chen, Hanye Shi, Xingyu Cheng, Xiaoxu Wang, Zongjie Li, Donghua Shao, Ke Liu, Jianchao Wei, Beibei Li, Jian Wang, Bin Zhou, Zhiyong Ma, Yafeng Qiu

Publikováno v: Veterinary Sciences, Vol 9, Iss 7, p 342 (2022)

HPS_06257 has been identified as an important protective antigen against Glaesserella parasuis infection. However, little is known about the role of HPS_06257 in the protective immune response. A whole-genome data analysis showed that among 18 isolat

Externí odkaz: https://doaj.org/article/7766df7a19334b259ed4d1951e4bcc49

SIRPα Suppresses Response to Therapeutic Antibodies by Nurse Like Cells From Chronic Lymphocytic Leukemia Patients

Autor: Yu-Chen Enya Chen, Melinda Burgess, Sally Mapp, Peter Mollee, Devinder Gill, Antje Blumenthal, Nicholas A. Saunders

Publikováno v: Frontiers in Immunology, Vol 11 (2021)

Targeted antibody therapies improve outcomes for chronic lymphocytic leukemia (CLL) patients. However, resistance often develops. We have previously shown that resistance to therapeutic antibodies, by monocyte derived macrophages (referred to as nurs

Externí odkaz: https://doaj.org/article/b9578f6fa5824a12a011388f3633dbd1

γδ T cells suppress Plasmodium falciparum blood stage infection by direct killing and phagocytosis

Autor: Ricardo T. Gazzinelli, Jeffrey D. Dvorin, Judy Lieberman, Rafael B. Polidoro, Ângela C. Crespo, Sumit Sen Santara, Zhitao Liang, Dhelio Batista Pereira, Caroline Junqueira, Guilherme Castro, Sabrina Absalon

Publikováno v: Nature immunology
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Activated Vγ9Vδ2 (γδ2) T lymphocytes that sense parasite-produced phosphoantigens are expanded in Plasmodium falciparum–infected patients. Although previous studies suggested that γδ2 T cells help control erythrocytic malaria, whether γδ2 T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a2ac317932d52ba18a368ac0c36c968
http://europepmc.org/articles/PMC7906917

SARS-CoV-2 infects blood monocytes to activate NLRP3 and AIM2 inflammasomes, pyroptosis and cytokine release

Autor: Jonathan Abraham, Michael Filbin, F. Ho, Judy Lieberman, Erin Janssen, Shahin Ranjbar, Setu M. Vora, Upasana Das Adhikari, Caroline Beakes, Douglas S. Kwon, N. Russell, Hao Wu, Steven Bell, Chris Sander, M. Lewandrowski, Angela Crespo, Sarah Clark, Lauren A. Henderson, Caroline Junqueira, Sagi Ravid, Justin D. Margolin, Gautam Mehta, Kyle R. Kays, Blair Parry, Marcia B. Goldberg, Anne E. Goldfeld, J. Ingber, Lee Gehrke, Valerie Leger, L. B. de Lacerda

Publikováno v: Research Square
article-version (status) pre
article-version (number) 1

SARS-CoV-2 causes acute respiratory distress that can progress to multiorgan failure and death in a minority of patients. Although severe COVID-19 disease is linked to exuberant inflammation, how SARS-CoV-2 triggers inflammation is not understood. Mo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f348f6a51ed2135431f779526ccbd7c
https://doi.org/10.21203/rs.3.rs-153628/v1

Analysis and Fine Specificity of the HCMV-Specific Cell-Free and Cell-Associated Antibody-Dependent Cellular Phagocytosis (ADCP) Responses in Lung Transplant Recipients

Autor: Simone Eberhard, Irene Görzer, Peter Jaksch, Hannes Vietzen, Elisabeth Puchhammer-Stöckl

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 8206, p 8206 (2021)
Volume 22
Issue 15

Human Cytomegalovirus (HCMV) may cause severe infections in transplant recipients. HCMV-replication can be limited by HCMV-specific antibody responses. The impact of the antibody-dependent cellular phagocytosis (ADCP) on inhibition of HCMV-replicatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b943816fb0c098b016d942b123bd5c76
https://pubmed.ncbi.nlm.nih.gov/34360986