Zobrazeno 1 - 10
of 156
pro vyhledávání: '"antibody-based therapy"'
Autor:
Claire Scheffges, Jérôme Devy, Jérôme Giustiniani, Stessy Francois, Lucille Cartier, Yacine Merrouche, Arnaud Foussat, Stéphane Potteaux, Armand Bensussan, Anne Marie-Cardine
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-13 (2024)
Abstract Background Despite major therapeutic advances, triple-negative breast cancer (TNBC) still presents a worth prognosis than hormone receptors-positive breast cancers. One major issue relies in the molecular and mutational heterogeneity of TNBC
Externí odkaz:
https://doaj.org/article/d9b78278811a4ad596555e996432d64d
Publikováno v:
Biology, Vol 13, Iss 5, p 307 (2024)
Cancer immune evasion represents a leading hallmark of cancer, posing a significant obstacle to the development of successful anticancer therapies. However, the landscape of cancer treatment has significantly evolved, transitioning into the era of im
Externí odkaz:
https://doaj.org/article/74c5b7dd0fa34af9b6e0371bd9e0105a
Autor:
Hillary A. Vanderven, Stephen J. Kent
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Passive immunotherapies have been used to treat severe respiratory infections for over a century, with convalescent blood products from recovered individuals given to patients with influenza-related pneumonia as long ago as the Spanish flu pandemic.
Externí odkaz:
https://doaj.org/article/3fd86685f74d4d9db4c410a9f4a4cc45
Autor:
Per Flodbring Larsson, Richard Karlsson, Martuza Sarwar, Regina Miftakhova, Tianyan Wang, Azharuddin Sajid Syed Khaja, Julius Semenas, Sa Chen, Andreas Hedblom, Amjad Ali, Kristina Ekström‐Holka, Athanasios Simoulis, Anjani Kumar, Anette Gjörloff Wingren, Brian Robinson, Sun Nyunt Wai, Nigel P. Mongan, David M. Heery, Daniel Öhlund, Thomas Grundström, Niels Ødum, Jenny L. Persson
Publikováno v:
Molecular Oncology, Vol 16, Iss 13, Pp 2496-2517 (2022)
Low‐affinity immunoglobulin gamma Fc region receptor III‐A (FcγRIIIa) is a cell surface protein that belongs to a family of Fc receptors that facilitate the protective function of the immune system against pathogens. However, the role of FcγRII
Externí odkaz:
https://doaj.org/article/b9424d66238242208aa13b376f19daab
Akademický článek
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Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Amyotrophic Lateral Sclerosis (ALS) is a mid-life onset neurodegenerative disease that manifests its symptomatology with motor impairments and cognitive deficits overlapping with Frontotemporal Lobar Degeneration (FTLD). The etiology of ALS remains e
Externí odkaz:
https://doaj.org/article/677940c8688947009b4e499213572c04
Autor:
Hongping Ba, Rui Jiang, Meng Zhang, Bingjiao Yin, Jing Wang, Zhuoya Li, Baihua Li, Xiaoxi Zhou
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Soluble tumor necrosis factor-α (sTNF-α) plays an important role in colitis-associated cancer (CAC); however, little is known about transmembrane TNF-α (tmTNF-α). Here, we observed an increase in sTNF-α mainly in colitis tissues from an azoxymet
Externí odkaz:
https://doaj.org/article/00d245434c3549c38bc5b8a56356b623
Autor:
Mengqiao Xu, Xia Wang, Yanfang Pan, Xingpeng Zhao, Bin Yan, Changgeng Ruan, Lijun Xia, Yiming Zhao
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-11 (2019)
Abstract Background Podoplanin (PDPN), a transmembrane O-glycoprotein, is up-regulated in many tumors and is involved in tumor metastasis and malignant progression. In previous studies, we generated a functional blocking monoclonal antibody (mAb, SZ1
Externí odkaz:
https://doaj.org/article/1fd7ed218d594e588eb774176e964fe7
Autor:
Yahya Ashraf, Hanane Mansouri, Valérie Laurent-Matha, Lindsay B. Alcaraz, Pascal Roger, Séverine Guiu, Danielle Derocq, Gautier Robin, Henri-Alexandre Michaud, Helène Delpech, Marta Jarlier, Martine Pugnière, Bruno Robert, Anthony Puel, Lucie Martin, Flavie Landomiel, Thomas Bourquard, Oussama Achour, Ingrid Fruitier-Arnaudin, Alexandre Pichard, Emmanuel Deshayes, Andrei Turtoi, Anne Poupon, Joëlle Simony-Lafontaine, Florence Boissière-Michot, Nelly Pirot, Florence Bernex, William Jacot, Stanislas du Manoir, Charles Theillet, Jean-Pierre Pouget, Isabelle Navarro-Teulon, Nathalie Bonnefoy, André Pèlegrin, Thierry Chardès, Pierre Martineau, Emmanuelle Liaudet-Coopman
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-17 (2019)
Abstract Background Triple-negative breast cancer (TNBC) treatment is currently restricted to chemotherapy. Hence, tumor-specific molecular targets and/or alternative therapeutic strategies for TNBC are urgently needed. Immunotherapy is emerging as a
Externí odkaz:
https://doaj.org/article/29cfb2cf1cb546cb9c2f21a1f397c343
Autor:
Samis M. A. Zella, Judith Metzdorf, Emine Ciftci, Friederike Ostendorf, Siegfried Muhlack, Ralf Gold, Lars Tönges
Publikováno v:
Neurology and Therapy, Vol 8, Iss 1, Pp 29-44 (2018)
Abstract Symptomatic treatment options for Parkinson disease have steadily improved, and individualized therapeutic approaches are becoming established for every stage of the disease. However, disease-modifying therapy with a causal approach is still
Externí odkaz:
https://doaj.org/article/e6cf222deee84dccb0d7316d8d380572