Zobrazeno 1 - 10
of 45
pro vyhledávání: '"antibody-based biotherapeutic"'
Autor:
Xuekun Wang, Jin Xu, Qingcheng Guo, Zhenhua Li, Jiawei Cao, Rongrong Fu, Mengjiao Xu, Xiang Zhao, Fugui Wang, Xinmeng Zhang, Taimin Dong, Xu Li, Weizhu Qian, Shen Hou, Lusha Ji, Dapeng Zhang, Huaizu Guo
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
The Chinese hamster ovarian (CHO) cells serve as a common choice in biopharmaceutical production, traditionally cultivated in stirred tank bioreactors (STRs). Nevertheless, the pursuit of improved protein quality and production output for commercial
Externí odkaz:
https://doaj.org/article/f622f91f8c874caca261685bcf9c9c2e
Akademický článek
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Akademický článek
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Autor:
Comeau SR; Computational Biochemistry and Bioinformatics Group, Biotherapeutics Discovery, Boehringer Ingelheim Pharmaceuticals Inc., Ridgefield, CT, USA., Thorsteinson N; Scientific Services Manager, Biologics, Chemical Computing Group ULC, Montreal, QC, Canada., Kumar S; Computational Biochemistry and Bioinformatics Group, Biotherapeutics Discovery, Boehringer Ingelheim Pharmaceuticals Inc., Ridgefield, CT, USA. Sandeep_2.Kumar@boehringer-ingelheim.com.
Publikováno v:
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2023; Vol. 2552, pp. 309-321.
Autor:
Sanghati Bhattacharya, Deepika Sarin
Publikováno v:
LCGC North America. :27-31
Monoclonal antibodies (mAbs) dominate the pipelines in the biopharmaceutical industry today. Being complex products, this class of molecules has numerous critical quality attributes (CQAs). Their thorough characterization is a necessary and critical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5200f4d98f3e4e67aba7e969730f8af3
https://doi.org/10.56530/lcgc.na.cz9881a2
https://doi.org/10.56530/lcgc.na.cz9881a2
Publikováno v:
Computer-Aided Antibody Design ISBN: 9781071626085
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::884584cbf422e9f21503c257cf09645f
https://doi.org/10.1007/978-1-0716-2609-2_17
https://doi.org/10.1007/978-1-0716-2609-2_17
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2552
Affinity maturation is an important stage in biologic drug discovery as is the natural process of generating an immune response inside the human body. In this chapter, we describe in silico approaches to affinity maturation via a worked example. Both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cf2b607feda00c0b5bb225ab38a35674
https://pubmed.ncbi.nlm.nih.gov/36346600
https://pubmed.ncbi.nlm.nih.gov/36346600
Publikováno v:
mAbs; Jan-Dec2023, Vol. 15 Issue 1, p1-29, 29p
Autor:
Licari, Giuseppe, Martin, Kyle P., Crames, Maureen, Mozdzierz, Joseph, Marlow, Michael S., Karow-Zwick, Anne R., Kumar, Sandeep, Bauer, Joschka
Publikováno v:
Molecular Pharmaceutics; February 2023, Vol. 20 Issue: 2 p1096-1111, 16p
Publikováno v:
AAPS Journal; Jan2017, Vol. 19 Issue 1, p313-319, 7p