Zobrazeno 1 - 10
of 85
pro vyhledávání: '"antibody mimetics"'
Autor:
Tomoyuki Ito, Thuy Duong Nguyen, Yutaka Saito, Yoichi Kurumida, Hikaru Nakazawa, Sakiya Kawada, Hafumi Nishi, Koji Tsuda, Tomoshi Kameda, Mitsuo Umetsu
Publikováno v:
mAbs, Vol 15, Iss 1 (2023)
ABSTRACTDespite the advances in surface-display systems for directed evolution, variants with high affinity are not always enriched due to undesirable biases that increase target-unrelated variants during biopanning. Here, our goal was to design a li
Externí odkaz:
https://doaj.org/article/006271d38f2946dbaf222d586d863779
Autor:
Maryam Ehsasatvatan, Bahram Baghban Kohnehrouz, Ashraf Gholizadeh, Hamideh Ofoghi, Dariush Shanehbandi
Publikováno v:
Biological Research, Vol 55, Iss 1, Pp 1-18 (2022)
Abstract Background Designed mimetic molecules are attractive tools in biopharmaceuticals and synthetic biology. They require mass and functional production for the assessment of upcoming challenges in the near future. The DARPin family is considered
Externí odkaz:
https://doaj.org/article/4420ebf8874f4362a2d00c6d69bd918a
Publikováno v:
Veterinary Research, Vol 52, Iss 1, Pp 1-6 (2021)
Abstract Antibody mimetics may be used for various biomedical applications, especially those for which conventional antibodies are ineffective. In this study, we developed a smaller molecular chicken IgY mimetic peptide (IgY-peptide) based on the com
Externí odkaz:
https://doaj.org/article/92ceca51784c496a8436e3cb52ce3335
Akademický článek
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Publikováno v:
Veterinary Research, Vol 52, Iss 1, Pp 1-6 (2021)
Veterinary Research
Veterinary Research
Antibody mimetics may be used for various biomedical applications, especially those for which conventional antibodies are ineffective. In this study, we developed a smaller molecular chicken IgY mimetic peptide (IgY-peptide) based on the complementar
Autor:
Marcello Mascini, Emre Dikici, Marta Robles Mañueco, Julio A. Perez-Erviti, Sapna K. Deo, Dario Compagnone, Joseph Wang, José M. Pingarrón, Sylvia Daunert
Publikováno v:
Biomolecules, Vol 9, Iss 9, p 498 (2019)
Herein, and in contrast to current production of anti-Zika virus antibodies, we propose a semi-combinatorial virtual strategy to select short peptides as biomimetic antibodies/binding agents for the detection of intact Zika virus (ZIKV) particles. Th
Externí odkaz:
https://doaj.org/article/6d27e845d84e48b2aabcd0c7d2591063
Autor:
Francesca Torrini, Laura Caponi, Andrea Bertolini, Pasquale Palladino, Francesca Cipolli, Alessandro Saba, Aldo Paolicchi, Simona Scarano, Maria Minunni
Publikováno v:
Analytical and bioanalytical chemistry. 414(18)
An original biomimetic enzyme-linked immunoassay (BELISA) to target the small peptide hormone gonadorelin is presented. This peptide has been recently listed among the substances banned in sports by the World Antidoping Agency (WADA) since its misuse
Akademický článek
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Autor:
Alexander S. Sobolev
Publikováno v:
Acta Naturae
Development of vehicles for the subcellular targeted delivery of biologically active agents is very promising for the purposes of translational medicine. This review summarizes the results obtained by researchers from the Laboratory of Molecular Gene
Autor:
Blažková, Kristýna
Development of nanochemical tools targeting receptors in the tumor microenvironment Targeting the receptors in the tumor microenvironment is crucial for the future development of targeted therapies, precision medicine and immunotherapy of cancer. The
Externí odkaz:
http://www.nusl.cz/ntk/nusl-456244